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Biology and Biochemistry

D-Index
91
Citations
33931
World Ranking
2303
National Ranking
1231

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Michael E. Selsted is affiliated with the University of Southern California in the United States. Their research activity spans several interconnected fields, primarily focusing on Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Within these domains, Selsted's work addresses core subfields such as Microbiology, Immunology, Molecular Biology, Rheumatology, and Oncology.

The main scientific topics covered by their research include Antimicrobial Peptides and Activities, Immune Response and Inflammation, Rheumatoid Arthritis Research and Therapies, HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, Protein Hydrolysis and Bioactive Peptides, and Biochemical and Structural Characterization.

Selsted's recent scholarly contributions consist of multiple papers published between 2020 and 2023. Notable recent publications include the following:

  • Host Defense Peptides as Templates for Antifungal Drug Development, 2020, Journal of Fungi
  • Preclinical Pharmacokinetics and Safety of Intravenous RTD-1, 2022, Antimicrobial Agents and Chemotherapy
  • A host-directed macrocyclic peptide therapeutic for MDR gram negative bacterial infections, 2021, Scientific Reports
  • Inhibition of miR-146a Expression and Regulation of Endotoxin Tolerance by Rhesus Theta-Defensin-1, 2023, Mediators of Inflammation
  • Anti-Inflammatory Effects of RTD-1 in a Murine Model of Chronic Pseudomonas aeruginosa Lung Infection: Inhibition of NF-κB, Inflammasome Gene Expression, and Pro-IL-1β Biosynthesis, 2021, Antibiotics

Frequent coauthors who have collaborated multiple times with Selsted include André J. Ouellette, Dat Q. Tran, Justin B. Schaal, Katie Trinh, and Prasad Tongaonkar. Their collaborations span various publications contributing to the scholar's research breadth.

Selsted's work has been published in journals that frequently appear in their portfolio, including Journal of Fungi, Antimicrobial Agents and Chemotherapy, Scientific Reports, Mediators of Inflammation, and Antibiotics.

Recognition in their field includes membership in the Association of American Physicians. This affiliation underscores a professional acknowledgment within the medical and scientific community.

Best Publications

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

    Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  • Defensins. Natural peptide antibiotics of human neutrophils.

    T Ganz;M E Selsted;D Szklarek;S S Harwig

  • Mammalian Defensins in the Antimicrobial Immune Response

    Michael E. Selsted;André J. Ouellette

  • Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.

    Tokiyoshi Ayabe;Donald P. Satchell;Carole L. Wilson;William C. Parks

  • A Cyclic Antimicrobial Peptide Produced in Primate Leukocytes by the Ligation of Two Truncated α-Defensins

    Yi-Quan Tang;Jun Yuan;George Ösapay;Klara Ösapay

  • Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity.

    R. I. Lehrer;A. Barton;K. A. Daher;S. S.L. Harwig

  • Antimicrobial Peptides from Human Platelets

    Yi-Quan Tang;Michael R. Yeaman;Michael R. Yeaman;Michael E. Selsted

  • Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils.

    Michael E. Selsted;Michael J. Novotny;Wendy L. Morris;Yi Quan Tang

  • Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes.

    Bruce L. Kagan;Michael E. Selsted;Tomas Ganz;Robert I. Lehrer

  • Primary structures of three human neutrophil defensins.

    M E Selsted;S S Harwig;T Ganz;J W Schilling

  • Direct inactivation of viruses by human granulocyte defensins.

    K A Daher;M E Selsted;R I Lehrer

  • Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization.

    Christopher P. Hill;Jeff Yee;Michael E. Selsted;David Eisenberg

  • Monocyte-chemotactic activity of defensins from human neutrophils.

    Mary C. Territo;Tomas Ganz;Michael E. Selsted;Robert Lehrer

  • Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.

    Michael E Selsted;Yi Quan Tang;Wendy L. Morris;Patti A. McGuire

  • Structure, function, and membrane integration of defensins

    Stephen H White;William C Wimley;Michael E Selsted

  • Defensins: endogenous antibiotic peptides of animal cells.

    Robert I Lehrer;Tomas Ganz;Michael E Selsted

  • Neutrophils and Host Defense

    Robert I. Lehrer;Tomas Ganz;Michael E. Selsted;Bernard M. Babior

  • Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores.

    William C. Wimley;Michael E. Selsted;Stephen H. White

  • Enteric defensins: antibiotic peptide components of intestinal host defense.

    M E Selsted;S I Miller;A H Henschen;A J Ouellette

  • Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes

    M E Selsted;D Szklarek;R I Lehrer

Frequent Co-Authors

Andre J. Ouellette
Andre J. Ouellette University of Southern California
Robert I. Lehrer
Robert I. Lehrer University of California, Los Angeles
Tomas Ganz
Tomas Ganz University of California, Los Angeles
Stephen H. White
Stephen H. White University of California, Irvine
Arthur Pardi
Arthur Pardi University of Colorado Boulder
Wayne I. Lencer
Wayne I. Lencer Harvard University
Pieter C. Dorrestein
Pieter C. Dorrestein University of California, San Diego
Didier Merlin
Didier Merlin Georgia State University
Michael R. Yeaman
Michael R. Yeaman University of California, Los Angeles
Gabriele Bierbaum
Gabriele Bierbaum University Hospital Bonn

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