World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
16015
World Ranking
6399
National Ranking
2991

Overview

Wuyuan Lu is a researcher affiliated with the University of Maryland, Baltimore in the United States. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Within these broad disciplines, they have contributed notably to subfields including Molecular Biology, Microbiology, Immunology, Oncology, and Epidemiology.

Their research focuses on several main topics, with significant attention to antimicrobial peptides and activities, immune response and inflammation, biochemical and structural characterization, RNA interference and gene delivery, immunotherapy and immune responses, chemical synthesis and analysis, as well as advanced biosensing and bioanalysis techniques.

Wuyuan Lu has published extensively, with frequent collaborations and co-authorship with Chongbing Liao, Xiang Li, Gan Luo, Dan Xu, and Jin Yan. Their work has appeared repeatedly in certain scholarly venues:

  • Theranostics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Cellular and Infection Microbiology
  • Frontiers in Immunology
  • Journal of Controlled Release

Among recent publications authored or co-authored by Wuyuan Lu are the following significant papers:

  • "Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance" (2022, Frontiers in Cellular and Infection Microbiology)
  • "Defensins: A Double-Edged Sword in Host Immunity" (2020, Frontiers in Immunology)
  • "Chiral Protein Supraparticles for Tumor Suppression and Synergistic Immunotherapy: An Enabling Strategy for Bioactive Supramolecular Chirality Construction" (2020, Nano Letters)
  • "Defensins: The natural peptide antibiotic" (2021, Advanced Drug Delivery Reviews)
  • "A nano-predator of pathological MDMX construct by clearable supramolecular gold(I)-thiol-peptide complexes achieves safe and potent anti-tumor activity" (2021, Theranostics)

Best Publications

  • Human β-defensins

    M. Pazgier;D. M. Hoover;D. Yang;W. Lu

  • Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3

    Zhibin Wu;David M. Hoover;De Yang;Cyril Boulègue

  • α-Defensins in human innate immunity.

    Robert I. Lehrer;Wuyuan Lu

  • Human α-Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

    Hiutung Chu;Marzena Pazgier;Grace Jung;Sean Paul Nuccio

  • Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

    Marzena Pazgier;Min Liu;Guozhang Zou;Weirong Yuan

  • Antibacterial activity and specificity of the six human α-defensins

    Bryan Ericksen;Zhibin Wu;Wuyuan Lu;Robert I. Lehrer

  • Human α- and β-Defensins Block Multiple Steps in Herpes Simplex Virus Infection

    Ehsan Hazrati;Benjamin Galen;Wuyuan Lu;Wei Wang

  • Human beta-defensins suppress human immunodeficiency virus infection: potential role in mucosal protection.

    Lingling Sun;Catherine M. Finnegan;Tina Kish-Catalone;Robert Blumenthal

  • Human α-defensins block papillomavirus infection

    Christopher B. Buck;Patricia M. Day;Cynthia D. Thompson;Jacek Lubkowski

  • The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins

    David M. Hoover;Cyril Boulègue;De Yang;Joost J. Oppenheim

  • Antimicrobial Characterization of Human β-Defensin 3 Derivatives

    David M. Hoover;Zhibin Wu;Kenneth Tucker;Wuyuan Lu

  • Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II

    Erik de Leeuw;Changqing Li;Pengyun Zeng;Chong Li

  • D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms

    Min Liu;Chong Li;Marzena Pazgier;Changqing Li

  • Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.

    Agnieszka Szyk;Zhibin Wu;Kenneth Tucker;De Yang

  • Binding of amino acid side-chains to S1 cavities of serine proteinases

    Wuyuan Lu;Izydor Apostol;M.A. Qasim;Nicholas Warne

  • Dying and necrotic neutrophils are anti-inflammatory secondary to the release of α-defensins

    Katherine Miles;David J. Clarke;Wuyuan Lu;Zaneta Sibinska

  • Chiral Protein Supraparticles for Tumor Suppression and Synergistic Immunotherapy: An Enabling Strategy for Bioactive Supramolecular Chirality Construction

    Jin Yan;Yu Yao;Siqi Yan;Ruqing Gao

  • Induction of group A Streptococcus virulence by a human antimicrobial peptide

    Ioannis Gryllos;Hien J. Tran-Winkler;Ming-Fang Cheng;Hachung Chung

  • Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.

    Chong Li;Marzena Pazgier;Changqing Li;Weirong Yuan

  • Defensins: A Double-Edged Sword in Host Immunity.

    Dan Xu;Wuyuan Lu

Frequent Co-Authors

Weiyue Lu
Weiyue Lu Fudan University
Robert I. Lehrer
Robert I. Lehrer University of California, Los Angeles
Michael Laskowski
Michael Laskowski Purdue University West Lafayette
Peter X. Ma
Peter X. Ma University of Michigan–Ann Arbor
Robert C. Gallo
Robert C. Gallo University of South Florida
Anthony L. DeVico
Anthony L. DeVico University of Maryland, Baltimore
Jean K. Lim
Jean K. Lim Icahn School of Medicine at Mount Sinai
Andre J. Ouellette
Andre J. Ouellette University of Southern California
Stephen B. H. Kent
Stephen B. H. Kent University of Chicago
Stephen Anderson
Stephen Anderson Rutgers, The State University of New Jersey

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Wuyuan Lu

Trending Scientists

Recently Published Articles