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Immunology

D-Index
79
Citations
18546
World Ranking
1710
National Ranking
843

Overview

Charles R. Wira is affiliated with Dartmouth College in the United States. Their primary research focus lies in immunology and microbiology, with a total of 31 publications in this field. Their work extensively covers several subfields, including immunology, agronomy and crop science, reproductive medicine, oncology, and virology.

The scientist's research mainly addresses topics related to reproductive system and pregnancy, immune cell function and interaction, reproductive physiology in livestock, T-cell and B-cell immunology, IL-33, ST2, and ILC pathways, endometriosis research and treatment, and immunotherapy and immune responses.

Frequent publication venues for Charles R. Wira include Frontiers in Immunology, where they have published 7 papers, American Journal of Reproductive Immunology with 5 publications, Scientific Reports and Immunity & Ageing with 2 publications each, and Aging Cell with 1 publication.

They have contributed to several notable recent papers:

  • The impact of aging on innate and adaptive immunity in the human female genital tract, 2021, Aging Cell
  • Endometrial Cancer Suppresses CD8+ T Cell-Mediated Cytotoxicity in Postmenopausal Women, 2021, Frontiers in Immunology
  • Differential Cytotoxic Function of Resident and Non-resident CD8+ T Cells in the Human Female Reproductive Tract Before and After Menopause, 2020, Frontiers in Immunology
  • Direct and Indirect endocrine-mediated suppression of human endometrial CD8+T cell cytotoxicity, 2021, Scientific Reports
  • Aging modifies endometrial dendritic cell function and unconventional double negative T cells in the human genital mucosa, 2023, Immunity & Ageing

Charles R. Wira frequently collaborates with several co-authors, including Marta Rodríguez-García and Mickey V. Patel, each having collaborated on over a dozen publications. Other frequent collaborators include Zheng Shen, Shihoko Komine-Aizawa, and Adrian Erlebacher.

Best Publications

  • Innate and adaptive immunity in female genital tract: cellular responses and interactions.

    Charles R. Wira;John V. Fahey;Charles L. Sentman;Patricia A. Pioli

  • Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.

    Michael D Hill;Mayank Goyal;Bijoy K Menon;Raul G Nogueira

  • Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells.

    Todd M Schaefer;Kristin Desouza;John V Fahey;Kenneth W Beagley

  • Epithelial Cells in the Female Reproductive Tract: a Central Role as Sentinels of Immune Protection

    Charles R. Wira;Katherine S. Grant-Tschudy;Margaret A. Crane-Godreau;Margaret A. Crane-Godreau

  • A new strategy to understand how HIV infects women: identification of a window of vulnerability during the menstrual cycle.

    Charles R Wira;John V Fahey

  • Flow Cytometric Analysis of Leukocytes in the Human Female Reproductive Tract: Comparison of Fallopian Tube, Uterus, Cervix, and Vagina

    A L Givan;H D White;J E Stern;E Colby

  • Differential expression of Toll-like receptors 2 and 4 in tissues of the human female reproductive tract.

    Patricia A. Pioli;Eyal Amiel;Todd M. Schaefer;John E. Connolly

  • CD3+ CD8+ CTL activity within the human female reproductive tract: influence of stage of the menstrual cycle and menopause.

    H D White;K M Crassi;A L Givan;J E Stern

  • Glucocorticoid-receptor complexes and the earliest steps in the action of glucocorticoids on thymus cells

    A. Munck;C. Wira;D.A. Young;K.M. Mosher

  • Innate Immunity in the Human Female Reproductive Tract: Antiviral Response of Uterine Epithelial Cells to the TLR3 Agonist Poly(I:C)

    Unknown

  • Vascular Endothelial Growth Factor C Facilitates Immune Tolerance and Endovascular Activity of Human Uterine NK Cells at the Maternal-Fetal Interface

    Satyan S. Kalkunte;Teddy F. Mselle;Wendy E. Norris;Charles R. Wira

  • Unique CD8+ T cell-rich lymphoid aggregates in human uterine endometrium

    Grant R. Yeaman;Paul M. Guyre;Michael W. Fanger;Jane E. Collins

  • Sex Hormone Regulation of Innate Immunity in the Female Reproductive Tract: The Role of Epithelial Cells in Balancing Reproductive Potential with Protection against Sexually Transmitted Pathogens

    Unknown

  • Recruitment of Uterine NK Cells: Induction of CXC Chemokine Ligands 10 and 11 in Human Endometrium by Estradiol and Progesterone

    Charles L. Sentman;Sarah K. Meadows;Charles R. Wira;Mikael Eriksson

  • Effects of estradiol and progesterone on susceptibility and early immune responses to Chlamydia trachomatis infection in the female reproductive tract.

    Charu Kaushic;Fan Zhou;Andrew D. Murdin;Charles R. Wira

  • Glucocorticoid-Receptor Complexes in Rat Thymus Cells "CYTOPLASMIC"-NUCLEAR TRANSFORMATIONS

    Charles R. Wira;Allan Munck

  • IFN-gamma is produced by polymorphonuclear neutrophils in human uterine endometrium and by cultured peripheral blood polymorphonuclear neutrophils.

    Grant R. Yeaman;Jane E. Collins;Janet K. Currie;Paul M. Guyre

  • Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-β

    Mikael Eriksson;Sarah K. Meadows;Charles R. Wira;Charles L. Sentman

  • Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract

    Unknown

  • Antigen-presenting cells in the female reproductive tract: influence of sex hormones on antigen presentation in the vagina.

    C R Wira;R M Rossoll

  • Sex steroid hormone regulation of IgA and IgG in rat uterine secretions

    Charles R. Wira;Carola P. Sandoe

  • Estradiol Regulates Expression of Estrogen Receptor ERα46 in Human Macrophages

    Amy J. Murphy;Paul M. Guyre;Charles R. Wira;Patricia A. Pioli

  • Expression and secretion of antiviral factors by trophoblast cells following stimulation by the TLR-3 agonist, Poly(I : C)

    Vikki M. Abrahams;Todd M. Schaefer;John V. Fahey;Irene Visintin

  • Effect of Menstrual Status on Antibacterial Activity and Secretory Leukocyte Protease Inhibitor Production by Human Uterine Epithelial Cells in Culture

    John V. Fahey;Charles R. Wira

Frequent Co-Authors

Charles L. Sentman
Charles L. Sentman Dartmouth College
Paul M. Guyre
Paul M. Guyre Dartmouth College
David A. Sullivan
David A. Sullivan Massachusetts Eye and Ear Infirmary
Susan Cu-Uvin
Susan Cu-Uvin Brown University
Michael W. Fanger
Michael W. Fanger Dartmouth College
Allan Munck
Allan Munck Dartmouth College
Paul K. Wallace
Paul K. Wallace Roswell Park Cancer Institute
John C. Kappes
John C. Kappes University of Alabama at Birmingham
Mikael Eriksson
Mikael Eriksson Karolinska Institute
Jose R. Conejo-Garcia
Jose R. Conejo-Garcia Duke University

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