World's Best Scientists 2026 revealed!

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Immunology

D-Index
77
Citations
20312
World Ranking
1829
National Ranking
37

Medicine

D-Index
77
Citations
20312
World Ranking
18487
National Ranking
780

Overview

Rupert Kaul is affiliated with the University of Toronto in Canada. Their research is primarily situated within the fields of Medicine and Immunology and Microbiology, with a significant focus on Epidemiology, Infectious Diseases, and Microbiology as subfields. Their work intersects multiple topics related to reproductive and sexual health as well as infectious diseases.

The main topics addressed in Rupert Kaul's research include:

  • Reproductive tract infections research
  • Sex work and related issues
  • HIV/AIDS Research and Interventions
  • HIV, Drug Use, Sexual Risk
  • Adolescent Sexual and Reproductive Health
  • Genital Health and Disease
  • HIV Research and Treatment

Rupert Kaul has coauthored frequently with several researchers, including:

  • Sanja Huibner (28 publications)
  • Tara Beattie (20 publications)
  • Bryan Coburn (17 publications)
  • Jessica L. Prodger (16 publications)
  • Rhoda Kabuti (16 publications)

The scientist's recent notable publications are:

  • "Sustained effect of LACTIN-V (Lactobacillus crispatus CTV-05) on genital immunology following standard bacterial vaginosis treatment: results from a randomised, placebo-controlled trial," 2022, The Lancet Microbe
  • "Beyond bacterial vaginosis: vaginal lactobacilli and HIV risk," 2021, Microbiome
  • "Penile bacteria associated with HIV seroconversion, inflammation, and immune cells," 2021, JCI Insight
  • "Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses," 2022, JCI Insight
  • "Longitudinal Assessment of SARS-CoV-2-Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multicytokine Proliferative Responses, with Greater Immunity Associated with Disease Severity," 2022, Journal of Virology

Rupert Kaul has published frequently in several venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory) - 8 publications
  • Microbiome - 5 publications
  • SSRN Electronic Journal - 5 publications
  • The Journal of Immunology - 4 publications
  • PLoS ONE - 4 publications

Best Publications

  • Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

    R. Brad Jones;Lishomwa C Ndhlovu;Jason D. Barbour;Prameet M. Sheth

  • Population-Based Surveillance for Group A Streptococcal Necrotizing Fasciitis: Clinical Features, Prognostic Indicators, and Microbiologic Analysis of Seventy-Seven Cases

    Rupert Kaul;Allison McGeer;Donald E Low;Karen Green

  • Intravenous Immunoglobulin Therapy for Streptococcal Toxic Shock Syndrome—A Comparative Observational Study

    Rupert Kaul;Allison McGeer;Anna Norrby-Teglund;Malak Kotb

  • HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.

    Rupert Kaul;Francis A. Plummer;Francis A. Plummer;Joshua Kimani;Tao Dong

  • Perforin Expression Directly Ex Vivo by HIV-Specific CD8 + T-Cells Is a Correlate of HIV Elite Control

    Adam R. Hersperger;Florencia Pereyra;Martha Nason;Korey R. Demers

  • The integrin α4β7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

    Claudia Cicala;Elena Martinelli;Jonathan P. McNally;Diana J. Goode

  • HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers.

    Rupert Kaul;Daria Trabattoni;Job J. Bwayo;Donatella Arienti

  • Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial.

    Rupert Kaul;Joshua Kimani;Nico J. Nagelkerke;Karoline Fonck

  • Intravaginal Practices, Bacterial Vaginosis, and HIV Infection in Women: Individual Participant Data Meta-analysis

    Nicola Low;Matthew F. Chersich;Matthew F. Chersich;Kurt Schmidlin;Matthias Egger

  • Hormonal Contraception and the Risk of HIV Acquisition: An Individual Participant Data Meta-analysis

    Charles S. Morrison;Pai Lien Chen;Cynthia Kwok;Jared M. Baeten

  • Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication.

    Tae Wook Chun;J. Shawn Justement;Danielle Murray;Claire W. Hallahan

  • Sexual Risk Factors for HIV Infection in Early and Advanced HIV Epidemics in Sub-Saharan Africa: Systematic Overview of 68 Epidemiological Studies

    Li Chen;Prabhat Jha;Bridget Stirling;Bridget Stirling;Sema K. Sgaier

  • Mucosal and Plasma IgA from HIV-1-Exposed Uninfected Individuals Inhibit HIV-1 Transcytosis Across Human Epithelial Cells

    Claudia Devito;Kristina Broliden;Rupert Kaul;Lennart Svensson

  • Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses

    Rupert Kaul;Sarah L. Rowland-Jones;Joshua Kimani;Tao Dong

  • Identification of an innate T helper type 17 response to intestinal bacterial pathogens

    Kaoru Geddes;Stephen J Rubino;Joao G Magalhaes;Catherine Streutker

  • Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV-susceptible target cells.

    Kelly B. Arnold;Adam D. Burgener;Adam D. Burgener;Adam D. Burgener;Kenzie D. M. Birse;Kenzie D. M. Birse;Laura. Romas;Laura. Romas

  • CD8+ lymphocytes respond to different HIV epitopes in seronegative and infected subjects

    Rupert Kaul;Tao Dong;Francis A. Plummer;Joshua Kimani

  • The Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmission.

    Lyle R McKinnon;Lyle R McKinnon;Sharon L Achilles;Catriona S Bradshaw;Adam Burgener

  • Quality and quantity: mucosal CD4+ T cells and HIV susceptibility.

    Lyle R. McKinnon;Rupert Kaul

  • Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tract.

    Anuradha Rebbapragada;Charles Wachihi;Christopher Pettengell;Sherzana Sunderji

  • Plasma from patients with severe invasive group A streptococcal infections treated with normal polyspecific IgG inhibits streptococcal superantigen-induced T cell proliferation and cytokine production.

    Anna Norrby-Teglund;Rupert Kaul;Donald E. Low;Allison McGeer

  • Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate.

    Claudia Devito;Jorma Hinkula;Rupert Kaul;Lucia Lopalco

Frequent Co-Authors

Joshua Kimani
Joshua Kimani University of Manitoba
Francis A. Plummer
Francis A. Plummer University of Manitoba
Colin Kovacs
Colin Kovacs University of Toronto
Mario A. Ostrowski
Mario A. Ostrowski University of Toronto
Job J. Bwayo
Job J. Bwayo University of Nairobi
Sarah Rowland-Jones
Sarah Rowland-Jones University of Sheffield
Stephen Moses
Stephen Moses University of Manitoba
Walter Jaoko
Walter Jaoko University of Nairobi
Keith R. Fowke
Keith R. Fowke University of Manitoba
Tony Mazzulli
Tony Mazzulli University Health Network

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