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Immunology

D-Index
61
Citations
15249
World Ranking
3217
National Ranking
78

Overview

Colin Kovacs is affiliated with the University of Toronto in Canada. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on Infectious Diseases, Virology, Immunology, Epidemiology, and Obstetrics and Gynecology.

The scientist's work addresses a number of main topics, including:

  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • HIV/AIDS drug development and treatment
  • HIV/AIDS Research and Interventions
  • Immune Cell Function and Interaction
  • COVID-19 Impact on Reproduction
  • Vaccine Coverage and Hesitancy

Colin Kovacs has published extensively in several research venues, with frequent contributions to:

  • Journal of Virology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • AIDS
  • Nature Communications

Recent papers associated with Colin Kovacs include:

  • "BCL-2 antagonism sensitizes cytotoxic T cell-resistant HIV reservoirs to elimination ex vivo" (2020, Journal of Clinical Investigation)
  • "HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA)" (2021, Nature Communications)
  • "The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy" (2023, Journal of Clinical Investigation)
  • "COVID-19 vaccine immunogenicity in people with HIV" (2022, AIDS)
  • "Asymptomatic neurocognitive impairment is a risk for symptomatic decline over a 3-year study period" (2020, AIDS)

Frequent co-authors of Colin Kovacs include:

  • Erika Benko
  • R. Brad Jones
  • Mario Ostrowski
  • Yanqin Ren
  • Szu-Han Huang

Best Publications

  • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

    Janet D Siliciano;Joleen Kajdas;Diana Finzi;Thomas C Quinn;Thomas C Quinn

  • Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

    R. Brad Jones;Lishomwa C Ndhlovu;Jason D. Barbour;Prameet M. Sheth

  • Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals.

    Domenico Mavilio;Gabriella Lombardo;Janet Benjamin;Diana Kim

  • Rapid and durable antiretroviral effect of the HIV-1 Integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results of a 48-week controlled study.

    Martin Markowitz;Bach-Yen Nguyen;Eduardo Gotuzzo;Fernando Mendo

  • Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals.

    Martin Markowitz;Javier O Morales-Ramirez;Bach-Yen Nguyen;Colin M Kovacs

  • Perforin Expression Directly Ex Vivo by HIV-Specific CD8 + T-Cells Is a Correlate of HIV Elite Control

    Adam R. Hersperger;Florencia Pereyra;Martha Nason;Korey R. Demers

  • Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape.

    Ross A. Pollack;R. Brad Jones;Mihaela Pertea;Katherine M. Bruner

  • Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects.

    Johane P. Allard;Elaheh Aghdassi;Jenny Chau;Carolyn Tam

  • HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir

    Tae Wook Chun;David C. Nickle;J. Shawn Justement;Danielle Large

  • Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication.

    Tae Wook Chun;J. Shawn Justement;Danielle Murray;Claire W. Hallahan

  • Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily.

    Susan Moir;Angela Malaspina;Oxana K. Pickeral;Eileen T. Donoghue

  • Distinct Transcriptional Profiles in Ex Vivo CD4+ and CD8+ T Cells Are Established Early in Human Immunodeficiency Virus Type 1 Infection and Are Characterized by a Chronic Interferon Response as Well as Extensive Transcriptional Changes in CD8+ T Cells

    Martin D. Hyrcza;Colin Kovacs;Mona Loutfy;Roberta Halpenny

  • Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes

    Richard Brad Jones;Rachel O'Connor;Stefanie Mueller;Maria Hottelet Foley

  • A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

    C J Kim;A Nazli;O L Rojas;D Chege

  • Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression.

    Adam R. Hersperger;Jeffrey N. Martin;Lucy Y. Shin;Prameet M. Sheth

  • Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection

    Domenico Mavilio;Gabriella Lombardo;Audrey Kinter;Manuela Fogli

  • Relationship Between Residual Plasma Viremia and the Size of HIV Proviral DNA Reservoirs in Infected Individuals Receiving Effective Antiretroviral Therapy

    Tae-Wook Chun;Danielle Murray;J. Shawn Justement;Claire W. Hallahan

  • Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells

    Szu Han Huang;Yanqin Ren;Allison S. Thomas;Dora Chan

  • CD25+ regulatory T cells isolated from HIV-infected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro.

    Audrey L. Kinter;Robin Horak;Melanie Sion;Lindsey Riggin

  • A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.

    R. Brad Jones;R. Brad Jones;Stefanie Mueller;Rachel O’Connor;Katherine Rimpel

  • Persistent HIV RNA shedding in semen despite effective antiretroviral therapy.

    Prameet M Sheth;Colin Kovacs;Kimdar S Kemal;R Brad Jones

Frequent Co-Authors

Mario A. Ostrowski
Mario A. Ostrowski University of Toronto
Rupert Kaul
Rupert Kaul University of Toronto
Bruce D. Walker
Bruce D. Walker Harvard University
Anthony S. Fauci
Anthony S. Fauci Georgetown University
Tae-Wook Chun
Tae-Wook Chun National Institute of Allergy and Infectious Diseases
Sharon Walmsley
Sharon Walmsley University Health Network
Susan Moir
Susan Moir National Institute of Allergy and Infectious Diseases
Zabrina L. Brumme
Zabrina L. Brumme Simon Fraser University
Jean-Pierre Routy
Jean-Pierre Routy McGill University Health Centre
Claire W. Hallahan
Claire W. Hallahan National Institute of Allergy and Infectious Diseases

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