World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
18140
World Ranking
7344
National Ranking
184

Overview

Vania Broccoli is affiliated with Vita-Salute San Raffaele University in Italy. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant emphasis on Medicine. The scientist's work incorporates several subfields including Molecular Biology, Genetics, Cellular and Molecular Neuroscience, Neurology, and Epidemiology.

Their research topics cover a range of areas with a focus on Genetics and Neurodevelopmental Disorders, Mitochondrial Function and Pathology, CRISPR and Genetic Engineering, Parkinson's Disease Mechanisms and Treatments, RNA regulation and disease, Genomics and Chromatin Dynamics, and Endoplasmic Reticulum Stress and Disease.

Vania Broccoli has frequently published in the following venues:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • Stem Cell Research
  • Cell Reports

Frequent co-authors in their publications include Angelo Iannielli, Serena Giannelli, Mirko Luoni, Luca Massimino, and Alessandro Sessa.

Some of the recent papers authored or co-authored by Vania Broccoli are:

  • Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity, 2021, Nature Communications
  • In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy, 2020, Brain
  • Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion, 2022, Science Immunology
  • Frataxin gene editing rescues Friedreich's ataxia pathology in dorsal root ganglia organoid-derived sensory neurons, 2020, Nature Communications
  • Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome, 2022, Nature Communications

Best Publications

  • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

    Marius Wernig;Jian Ping Zhao;Jan Pruszak;Eva Hedlund

  • Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

    Massimiliano Caiazzo;Maria Teresa Dell’Anno;Elena Dvoretskova;Dejan Lazarevic;Dejan Lazarevic

  • Mapping Wnt/β-catenin signaling during mouse development and in colorectal tumors

    Silvia Maretto;Michelangelo Cordenonsi;Sirio Dupont;Paola Braghetta

  • The meso-angioblast: A multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues

    Maria G. Minasi;Mara Riminucci;Luciana De Angelis;Ugo Borello

  • FOXG1 Is Responsible for the Congenital Variant of Rett Syndrome

    Francesca Ariani;Giuseppe Hayek;Dalila Rondinella;Rosangela Artuso

  • Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

    Alessandro Sessa;Chai an Mao;Anna Katerina Hadjantonakis;William H. Klein

  • Site-specific integration and tailoring of cassette design for sustainable gene transfer.

    Angelo Lombardo;Daniela Cesana;Pietro Genovese;Bruno Di Stefano

  • CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome

    Francesca Mari;Sara Azimonti;Ilaria Bertani;Fabrizio Bolognese

  • The caudal limit of Otx2 expression positions the isthmic organizer

    Vania Broccoli;Edoardo Boncinelli;Wolfgang Wurst

  • Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

    Fatima Ferreirinha;Angelo Quattrini;Marinella Pirozzi;Valentina Valsecchi

  • Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy

    Francesco Saverio Tedesco;Francesco Saverio Tedesco;Mattia F. M. Gerli;Laura Perani;Sara Benedetti

  • Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis.

    Ferdinando Di Cunto;Sara Imarisio;Emilio Hirsch;Vania Broccoli

  • CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

    Sara Ricciardi;Federica Ungaro;Melanie Hambrock;Nils Rademacher

  • The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas.

    Patrick Collombat;Jacob Hecksher-Sørensen;Vania Broccoli;Jens Krull

  • Emx1 and Emx2 Show Different Patterns of Expression During Proliferation and Differentiation of the Developing Cerebral Cortex in the Mouse

    Massimo Gulisano;Vania Broccoli;Celia Pardini;Edoardo Boncinelli

  • Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model

    Sara Ricciardi;Elena M. Boggio;Stefano Grosso;Giuseppina Lonetti

  • Importance of Shank3 Protein in Regulating Metabotropic Glutamate Receptor 5 (mGluR5) Expression and Signaling at Synapses

    Chiara Verpelli;Elena Dvoretskova;Cinzia Vicidomini;Francesca Rossi

  • c-otx2 is expressed in two different phases of gastrulation and is sensitive to retinoic acid treatment in chick embryo.

    Laure Bally-Cuif;Massimo Gulisano;Vania Broccoli;Edoardo Boncinelli

  • Direct Conversion of Fibroblasts into Functional Astrocytes by Defined Transcription Factors

    Massimiliano Caiazzo;Serena Giannelli;Pierluigi Valente;Gabriele Lignani

  • CDKL5 Expression Is Modulated during Neuronal Development and Its Subcellular Distribution Is Tightly Regulated by the C-terminal Tail

    Laura Rusconi;Lisa Salvatoni;Laura Giudici;Ilaria Bertani

Frequent Co-Authors

Giulio Cossu
Giulio Cossu University of Manchester
Edoardo Boncinelli
Edoardo Boncinelli Vita-Salute San Raffaele University
Fabio Benfenati
Fabio Benfenati Italian Institute of Technology
Stephanie Schorge
Stephanie Schorge University College London
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Ahmed Mansouri
Ahmed Mansouri Max Planck Society
Raul R. Gainetdinov
Raul R. Gainetdinov Saint Petersburg State University
Alexander Dityatev
Alexander Dityatev German Center for Neurodegenerative Diseases
Dimitri M. Kullmann
Dimitri M. Kullmann University College London

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re interested in applying your Biology or Biochemistry skills toward a healthcare career, there are a variety of flexible online learning options to consider. Students seeking quick entry into the medical field might explore online medical assistant programs with financial aid, which offer essential clinical and administrative training and can often be completed in under a year.

For those looking to advance their clinical responsibilities, transitioning from Certified Medical Assistant to Licensed Practical Nurse is a common path. The cma to lpn route provides a structured, online pathway to higher qualifications and increased earning potential.

Students keen on deepening their scientific knowledge while maintaining schedule flexibility can enroll in online biology degrees, which often feature accelerated formats for faster completion. Additionally, for those inspired to become Registered Nurses, registered nurse online programs allow students to pursue an ASN or similar credential through a blend of online coursework and hands-on practicums.

These varied pathways offer accessible, reputable, and rewarding opportunities for students who want to turn their Biology and Biochemistry studies into a fulfilling healthcare career.

Best Scientists Citing Vania Broccoli

Trending Scientists

Recently Published Articles