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Nicolas Chomont

Nicolas Chomont

D-Index & Metrics

Immunology

D-Index
71
Citations
22145
World Ranking
2291
National Ranking
49

Overview

Nicolas Chomont is affiliated with the University of Montreal in Canada and contributes extensively to the fields of immunology and microbiology, with a significant focus on medicine. Their research encompasses virology, immunology, infectious diseases, epidemiology, and emergency medicine, addressing complex aspects of immune cell function and infectious disease mechanisms.

Their main topics of work include HIV research and treatment, immune cell function and interaction, HIV/AIDS research and interventions, T-cell and B-cell immunology, HIV-related health complications and treatments, HIV/AIDS drug development and treatment, and cytomegalovirus and herpesvirus research. This wide array highlights a specialization in understanding viral infections and immune responses, particularly related to HIV.

Frequent publication venues for Nicolas Chomont's work comprise bioRxiv (Cold Spring Harbor Laboratory), Journal of Virus Eradication, Journal of Virology, EBioMedicine, and Nature Communications. These platforms indicate an active engagement with both pre-publication and peer-reviewed scientific literature in the field of virology and immunology.

Their recent published papers include:

  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021 (2021, Nature Medicine)
  • The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies (2020, Cell Host & Microbe)
  • Recommendations for measuring HIV reservoir size in cure-directed clinical trials (2020, Nature Medicine)
  • Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART (2020, Nature Communications)
  • Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection (2020, Science Translational Medicine)

Their work frequently involves collaboration with other researchers, including Amélie Pagliuzza, Rémi Fromentin, Jean-Pierre Routy, Daniel E. Kaufmann, and Petronela Ancuța. These frequent coauthors contribute to a robust collaborative network in HIV and immunology research.

Best Publications

  • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

    Nicolas Chomont;Mohamed El-Far;Petronela Ancuta;Lydie Trautmann

  • Upregulation of PD-1 expression on HIV-specific CD8 + T cells leads to reversible immune dysfunction

    Lydie Trautmann;Loury Janbazian;Loury Janbazian;Nicolas Chomont;Elias A. Said

  • Towards an HIV cure: a global scientific strategy

    Steven G Deeks;Brigitte Autran;Ben Berkhout;Monsef Benkirane

  • The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

    Ole S. Søgaard;Mette E. Graversen;Steffen Leth;Rikke Olesen

  • Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.

    Julian H. Elliott;Fiona Wightman;Ajantha Solomon;Khader Ghneim

  • Immune activation and HIV persistence: implications for curative approaches to HIV infection

    Nichole R. Klatt;Nicolas Chomont;Daniel C. Douek;Steven G. Deeks

  • Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

    Rebecca M. Lynch;Eli Boritz;Emily E. Coates;Adam DeZure

  • International AIDS Society global scientific strategy: towards an HIV cure 2016

    Steven G Deeks;Sharon R Lewin;Anna Laura Ross;Jintanat Ananworanich

  • CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

    Rémi Fromentin;Wendy Bakeman;Mariam B. Lawani;Gabriela Khoury;Gabriela Khoury

  • Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants

    Bonnie Hiener;Bethany A. Horsburgh;John-Sebastian Eden;Kirston Barton

  • Peripheral Blood CCR4 + CCR6 + and CXCR3 + CCR6 + CD4 + T Cells Are Highly Permissive to HIV-1 Infection

    Annie Gosselin;Patricia Monteiro;Nicolas Chomont;Felipe Diaz-Griffero

  • Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.

    Jintanat Ananworanich;Alexandra Schuetz;Claire Vandergeeten;Irini Sereti

  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021.

    Steven G. Deeks;Nancie Archin;Paula Cannon;Simon Collins

  • Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection.

    Donn J. Colby;Lydie Trautmann;Lydie Trautmann;Suteeraporn Pinyakorn;Suteeraporn Pinyakorn;Louise Leyre

  • HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

    Didier Trono;Carine Van Lint;Christine Rouzioux;Eric Verdin

  • The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies.

    Lillian B. Cohn;Nicolas Chomont;Steven G. Deeks

  • Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection.

    Irini Sereti;Shelly J. Krebs;Nittaya Phanuphak;James L. Fletcher

  • A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals

    Francesco Andrea Procopio;Rémi Fromentin;Deanna A. Kulpa;Jessica H. Brehm

  • Cross-Clade Ultrasensitive PCR-Based Assays To Measure HIV Persistence in Large-Cohort Studies

    Claire Vandergeeten;Rémi Fromentin;Esther Merlini;Mariam B. Lawani

  • Interleukin-7 promotes HIV persistence during antiretroviral therapy

    Claire Vandergeeten;Rémi Fromentin;Sandrina DaFonseca;Mariam B. Lawani

  • HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART

    Jintanat Ananworanich;Jintanat Ananworanich;Nicolas Chomont;Leigh Ann Eller;Leigh Ann Eller;Eugene Kroon

  • Corrigendum: Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

    L. Trautmann;L. Janbazian;N. Chomont;E. A. Said

Frequent Co-Authors

Jean-Pierre Routy
Jean-Pierre Routy McGill University Health Centre
Rémi Fromentin
Rémi Fromentin University of Montreal
Jintanat Ananworanich
Jintanat Ananworanich Moderna Therapeutics (United States)
Sharon R. Lewin
Sharon R. Lewin University of Melbourne
Steven G. Deeks
Steven G. Deeks University of California, San Francisco
Merlin L. Robb
Merlin L. Robb Walter Reed Army Institute of Research
Petronela Ancuta
Petronela Ancuta University of Montreal
Laurent Bélec
Laurent Bélec Université Paris Cité
Nelson L. Michael
Nelson L. Michael Walter Reed Army Institute of Research
Rafick P. Sekaly
Rafick P. Sekaly Emory University

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