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Immunology

D-Index
81
Citations
33691
World Ranking
1539
National Ranking
28

Medicine

D-Index
81
Citations
33691
World Ranking
16421
National Ranking
689

Overview

Jean-Pierre Routy is affiliated with the McGill University Health Centre in Canada. Their research primarily focuses on medicine, immunology, and microbiology, with a significant output in HIV research and treatment alongside related fields.

Their main fields of study include:

  • Medicine
  • Immunology and Microbiology

Subfields that Routy has extensively contributed to are:

  • Immunology
  • Virology
  • Infectious Diseases
  • Epidemiology
  • Emergency Medicine

Research topics covered in Routy's work include:

  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • HIV-related health complications and treatments
  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • Cytomegalovirus and herpesvirus research
  • T-cell and B-cell Immunology

Routy has coauthored numerous publications with frequent collaborators such as Stéphane Isnard, Petronela Ancuța, Cécile Tremblay, Cecilia T. Costiniuk, and John Lin.

Their frequent publication venues include:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Viruses
  • AIDS
  • EBioMedicine

Notable recent papers authored or coauthored by Routy include:

  • Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo (2020, Nature)
  • Efficacy and Safety of Switching to Dolutegravir/Lamivudine Fixed-Dose 2-Drug Regimen vs Continuing a Tenofovir Alafenamide-Based 3- or 4-Drug Regimen for Maintenance of Virologic Suppression in Adults Living With Human Immunodeficiency Virus Type 1: Phase 3, Randomized, Noninferiority TANGO Study (2020, Clinical Infectious Diseases)
  • Sharing CD4+ T Cell Loss: When COVID-19 and HIV Collide on Immune System (2020, Frontiers in Immunology)
  • The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation (2020, Frontiers in Immunology)
  • Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART (2020, Nature Communications)

Best Publications

  • Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study

    Daniel D. Murray;Kazuo Suzuki;Matthew Law;Jonel Trebicka

  • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

    Nicolas Chomont;Mohamed El-Far;Petronela Ancuta;Lydie Trautmann

  • Upregulation of PD-1 expression on HIV-specific CD8 + T cells leads to reversible immune dysfunction

    Lydie Trautmann;Loury Janbazian;Loury Janbazian;Nicolas Chomont;Elias A. Said

  • Antiretroviral-Drug Resistance among Patients Recently Infected with HIV

    Susan J. Little;Sarah Holte;Jean Pierre Routy;Eric S. Daar

  • High Rates of Forward Transmission Events after Acute/Early HIV-1 Infection

    Bluma G Brenner;Michel Roger;Jean-Pierre Routy;Daniela Moisi

  • Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

    Elias A. Said;Franck P. Dupuy;Lydie Trautmann;Yuwei Zhang

  • Towards an HIV cure: a global scientific strategy

    Steven G Deeks;Brigitte Autran;Ben Berkhout;Monsef Benkirane

  • HIV-1 Viremia Prevents the Establishment of Interleukin 2–producing HIV-specific Memory CD4+ T Cells Endowed with Proliferative Capacity

    Souheil Antoine Younes;Bader Yassine-Diab;Alam R. Dumont;Alam R. Dumont;Mohamed Rachid Boulassel

  • Interleukin-2 therapy in patients with HIV infection.

    D. Abrams;Y. Lévy;M. H. Losso;A. Babiker

  • Peripheral Blood CCR4 + CCR6 + and CXCR3 + CCR6 + CD4 + T Cells Are Highly Permissive to HIV-1 Infection

    Annie Gosselin;Patricia Monteiro;Nicolas Chomont;Felipe Diaz-Griffero

  • Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

    Samantha Reiss;Amy E. Baxter;Kimberly M. Cirelli;Jennifer M. Dan;Jennifer M. Dan

  • HIV Infection Rapidly Induces and Maintains a Substantial Suppression of Thymocyte Proliferation

    Marie Lise Dion;Jean François Poulin;Rebeka Bordi;Myriam Sylvestre

  • Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study

    Y. Lévy;I. Sereti;G. Tambussi;J. P. Routy

  • Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.

    Christopher C. Nixon;Maud Mavigner;Gavin C. Sampey;Alyssa D. Brooks

  • Efficacy and Safety of Switching to Dolutegravir/Lamivudine Fixed-Dose 2-Drug Regimen vs Continuing a Tenofovir Alafenamide-Based 3- or 4-Drug Regimen for Maintenance of Virologic Suppression in Adults Living With Human Immunodeficiency Virus Type 1: Phase 3, Randomized, Noninferiority TANGO Study.

    Jean van Wyk;Faïza Ajana;Fiona Bisshop;Stéphane De Wit

  • Interleukin-7 promotes HIV persistence during antiretroviral therapy

    Claire Vandergeeten;Rémi Fromentin;Sandrina DaFonseca;Mariam B. Lawani

  • Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection.

    Bluma G. Brenner;Jean-Pierre Routy;Marco Petrella;Daniela Moisi

  • Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

    Hendrik Streeck;Jonathan S. Jolin;Ying Qi;Bader Yassine-Diab

  • Wide Variation in the Multiplicity of HIV-1 Infection among Injection Drug Users

    Katharine J. Bar;Hui Li;Annie Chamberland;Cecile Tremblay

  • Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial.

    Philippe Bégin;Jeannie Callum;Erin Jamula;Richard Cook

  • Corrigendum: Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

    L. Trautmann;L. Janbazian;N. Chomont;E. A. Said

  • Clinical outcome after lipectomy in the management of patients with human immunodeficiency virus-associated dorsocervical fat accumulation: An observational cohort study.

    Song Chen;Xi-En Gui;Qian Cao;Jean-Pierre Routy

Frequent Co-Authors

Nicolas Chomont
Nicolas Chomont University of Montreal
Petronela Ancuta
Petronela Ancuta University of Montreal
Rafick P. Sekaly
Rafick P. Sekaly Emory University
Pierre Côté
Pierre Côté University of Ontario Institute of Technology
Mark A. Wainberg
Mark A. Wainberg McGill University
Taisheng Li
Taisheng Li Peking Union Medical College Hospital
Bluma G. Brenner
Bluma G. Brenner McGill University
Rémi Fromentin
Rémi Fromentin University of Montreal
Marina B. Klein
Marina B. Klein McGill University
Susan J. Little
Susan J. Little University of California, San Diego

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