World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
83
Citations
26889
World Ranking
977
National Ranking
446

Medicine

D-Index
83
Citations
27068
World Ranking
15539
National Ranking
7833

Overview

Susan J. Little is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on medicine, with a strong emphasis on infectious diseases, epidemiology, virology, public health, environmental and occupational health, and molecular biology. The main topics covered by their work include HIV/AIDS research and interventions, HIV research and treatment, HIV, drug use, and sexual risk, HIV/AIDS drug development and treatment, SARS-CoV-2 and COVID-19 research, palliative care and end-of-life issues, and ethics in clinical research.

The scientist has contributed to a number of research papers in prominent venues. Recent papers include:

  • Clinical effectiveness of COVID-19 vaccination in solid organ transplant recipients, 2021, Transplant Infectious Disease
  • Immune correlates analysis of the ENSEMBLE single Ad26.COV2.S dose vaccine efficacy clinical trial, 2022, Nature Microbiology
  • Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection, 2023, Nature Communications
  • Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV, 2024, JAMA Cardiology
  • Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial, 2023, Nature Medicine

Their frequent co-authors include:

  • Davey M. Smith
  • Sanjay R. Mehta
  • Sara Gianella
  • Jeff Taylor
  • Paul Goepfert

Among the common publication venues are:

  • AIDS
  • Clinical Infectious Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Infectious Diseases
  • AIDS and Behavior

Susan J. Little's contribution to the field spans across a variety of crucial aspects of infectious disease research and public health. Their work has a significant concentration in HIV/AIDS research and treatment as well as studies related to the SARS-CoV-2 virus and COVID-19, reflecting substantial engagement in contemporary global health challenges.

Best Publications

  • Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.

    Victor Appay;P. Rod Dunbar;Margaret Callan;Paul Klenerman

  • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

    Pereyra F;Jia X;McLaren Pj

  • Rapid evolution of the neutralizing antibody response to HIV type 1 infection

    Douglas D. Richman;Terri Wrin;Susan J. Little;Christos J. Petropoulos

  • Antiretroviral-Drug Resistance among Patients Recently Infected with HIV

    Susan J. Little;Sarah Holte;Jean Pierre Routy;Eric S. Daar

  • Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells.

    Z. Q. Zhang;T. Schuler;M. Zupancic;Stephen W Wietgrefe

  • The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response. California Collaborative Treatment Group.

    Haubrich Rh;Little Sj;Currier Js;Forthal Dn

  • Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection

    L Papagno;C A Spina;A Marchant;M Salio

  • Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy.

    Tuan D Le;Edwina J. Wright;Davey M. Smith;Weijing He

  • Reduced Antiretroviral Drug Susceptibility Among Patients With Primary HIV Infection

    Susan J. Little;Eric S. Daar;Richard T. D'Aquila;Philip H. Keiser

  • Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection

    Simon D. W. Frost;Terri Wrin;Davey M. Smith;Sergei L. Kosakovsky Pond

  • Diagnosis of Primary HIV-1 Infection

    Eric S. Daar;Susan Little;Jacqui Pitt;Joanne Santangelo

  • Viral Dynamics of Acute HIV-1 Infection

    Susan J. Little;Angela R. McLean;Celsa A. Spina;Celsa A. Spina;Douglas D. Richman;Douglas D. Richman

  • Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1.

    Matthew C. Strain;Susan J. Little;Eric S. Daar;Diane V. Havlir

  • Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine.

    Ann R Falsey;Magdalena E Sobieszczyk;Ian Hirsch;Stephanie Sproule

  • 2008 American Association of Feline Practitioners' feline retrovirus management guidelines

    Julie Levy;Cynda Crawford;Katrin Hartmann;Regina Hofmann-Lehmann

  • Evidence for increased T cell turnover and decreased thymic output in HIV infection.

    Daniel C. Douek;Michael R. Betts;Brenna J. Hill;Susan J. Little

  • Persistence of Transmitted Drug Resistance among Subjects with Primary Human Immunodeficiency Virus Infection

    Susan J. Little;Simon D. W. Frost;Joseph K. Wong;Davey M. Smith

  • Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

    Hendrik Streeck;Jonathan S. Jolin;Ying Qi;Bader Yassine-Diab

  • A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection.

    Frederick M. Hecht;Lei Wang;Ann Collier;Susan Little

  • Transmission Fitness of Drug-Resistant Human Immunodeficiency Virus and the Prevalence of Resistance in the Antiretroviral-Treated Population

    Andrew J Leigh Brown;Simon D. W Frost;W. Christopher Mathews;Keith Dawson

  • 2020 AAFP Feline Retrovirus Testing and Management Guidelines

    Susan Little;Julie Levy;Katrin Hartmann;Regina Hofmann-Lehmann

Frequent Co-Authors

Davey M. Smith
Davey M. Smith University of California, San Diego
Douglas D. Richman
Douglas D. Richman University of California, San Diego
Martin Hoenigl
Martin Hoenigl University of California, San Diego
Sara Gianella
Sara Gianella University of California, San Diego
Eric S. Daar
Eric S. Daar Lundquist Institute
Sergei L. Kosakovsky Pond
Sergei L. Kosakovsky Pond Temple University
Joseph K. Wong
Joseph K. Wong University of California, San Francisco
Bruce D. Walker
Bruce D. Walker Harvard University
Frederick Hecht
Frederick Hecht University of California, San Francisco
Simon D. W. Frost
Simon D. W. Frost Microsoft (United States)

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