World's Best Scientists 2026 revealed!
Mario Clerici

Mario Clerici

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Immunology
Italy
2026
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Medicine
Italy
2023

D-Index & Metrics

Immunology

D-Index
113
Citations
51440
World Ranking
427
National Ranking
11

Medicine

D-Index
114
Citations
51649
World Ranking
4707
National Ranking
148

Research.com Recognitions

  • 2026 - Research.com Immunology in Italy Leader Award
  • 2025 - Research.com Immunology in Italy Leader Award
  • 2023 - Research.com Immunology in Italy Leader Award
  • 2023 - Research.com Medicine in Italy Leader Award
  • 2022 - Research.com Immunology in Italy Leader Award

Overview

Mario Clerici is affiliated with the University of Milan in Italy and has an extensive research career primarily in Medicine, with a focus on Infectious Diseases, Molecular Biology, Epidemiology, Neurology, and Immunology. Their work spans numerous investigations related to viral infections and immune response mechanisms.

The main topics of Clerici's research include:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Inflammasome and immune disorders
  • Herpesvirus Infections and Treatments
  • Infection Control and Ventilation
  • Cytomegalovirus and herpesvirus research
  • Parkinson's Disease Mechanisms and Treatments

Notable recent papers authored by or associated with Clerici include:

  • "Analysis of SARS-CoV-2 vertical transmission during pregnancy" (2020), published in Nature Communications
  • "UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication" (2021), published in Scientific Reports
  • "Alterations in Circulating Fatty Acid Are Associated With Gut Microbiota Dysbiosis and Inflammation in Multiple Sclerosis" (2020), published in Frontiers in Immunology
  • "Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis" (2021), published in The Lancet Rheumatology
  • "Computational Inference of Selection Underlying the Evolution of the Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2" (2020), published in Journal of Virology

Frequent co-authors collaborating with Clerici include:

  • Mara Biasin
  • Daria Trabattoni
  • Rachele Cagliani
  • Manuela Sironi
  • Franca Rosa Guerini

Clerici's research has been published repeatedly in a variety of scientific venues with notable frequency in:

  • International Journal of Molecular Sciences
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Cells
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Their body of work significantly contributes to the understanding of viral transmission, immune system dynamics, and the impact of infections on neurological and immune disorders. The combination of clinical and molecular research positions Clerici within a multidisciplinary framework addressing both pathogenesis and therapeutic strategies.

Best Publications

  • T Lymphocyte-Directed Gene Therapy for ADA− SCID: Initial Trial Results After 4 Years

    R. Michael Blaese;Kenneth W. Culver;A. Dusty Miller;Charles S. Carter

  • A TH1→TH2 switch is a critical step in the etiology of HIV infection

    Mario Clerici;Gene M. Shearer

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases.

    Daniel R. Lucey;Mario Clerici;Gene M. Shearer

  • Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging.

    M Clerici;N I Stocks;R A Zajac;R N Boswell

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • The Th1–Th2 hypothesis of HIV infection: new insights

    Mario Clerici;Gene M. Shearer

  • Molecular Evolution of Human Coronavirus Genomes

    Diego Forni;Rachele Cagliani;Mario Salvatore Clerici;Manuela Sironi

  • Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy.

    M. Marzi;A. Vigano;D. Trabattoni;M. L. Villa

  • Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection.

    Alan Sher;Ricardo T. Gazzinelli;Isabelle P. Oswald;Mario Clerici

  • Microbes and Alzheimer's disease

    Ruth F. Itzhaki;Ruth F. Itzhaki;Richard Lathe;Brian J. Balin;Melvyn J. Ball

  • Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals.

    Mario Clerici;Frances T. Hakim;David J. Venzon;Stephen Blatt

  • HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals.

    S Mazzoli;D Trabattoni;S Lo Caputo;S Piconi

  • Cell-Mediated Immune Response to Human Immunodeficiency Virus (HIV) Type 1 in Seronegative Homosexual Men with Recent Sexual Exposure to HIV-1

    Mario Clerici;Janis V. Giorgi;Janis V. Giorgi;Janis V. Giorgi;Chen Cheng Chou;Vaheideh K. Gudeman;Vaheideh K. Gudeman;Vaheideh K. Gudeman

  • The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

    Marina Saresella;Francesca La Rosa;Federica Piancone;Martina Zoppis

  • Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

    Mario Clerici;Daniel R. Lucey;Jay A. Berzofsky;Ligia A. Pinto

  • Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.

    Mario Clerici;Thomas A. Wynn;Jay A. Berzofsky;Stephen P. Blatt

  • Hemodynamic and Autonomic Adjustments to Real Life Stress Conditions in Humans

    Daniela Lucini;Guido Norbiato;Mario Clerici;Massimo Pagani

  • Probiotics and health: an evidence-based review.

    Paolo Aureli;Lucio Capurso;Anna Maria Castellazzi;Mario Clerici

  • Cytokine Production Patterns in Cervical Intraepithelial Neoplasia: Association With Human Papillomavirus Infection

    M. Clerici;Marcello Merola;E. Ferrario;D. Trabattoni

  • Redistribution of body fat in HIV-infected women undergoing combined antiretroviral therapy

    Cristina Gervasoni;Anna Lisa Ridolfo;Giuliana Trifirò;Sara Santambrogio

  • ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.

    L A Pinto;J Sullivan;J A Berzofsky;M Clerici

  • Analysis of SARS-CoV-2 vertical transmission during pregnancy.

    Claudio Fenizia;Mara Biasin;Irene Cetin;Patrizia Vergani

  • Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

    Matteo Fumagalli;Uberto Pozzoli;Rachele Cagliani;Giacomo P. Comi

Frequent Co-Authors

Daria Trabattoni
Daria Trabattoni University of Milan
Manuela Sironi
Manuela Sironi University of Turin
Gene M. Shearer
Gene M. Shearer National Institutes of Health
Marina Saresella
Marina Saresella MRC Laboratory of Molecular Biology
Andrea Gori
Andrea Gori University of Milan
Pasquale Ferrante
Pasquale Ferrante University of Milan
Massimo Galli
Massimo Galli University of Milan
Nereo Bresolin
Nereo Bresolin University of Milan
Jay A. Berzofsky
Jay A. Berzofsky National Institutes of Health
Giuliano Rizzardini
Giuliano Rizzardini ASST Fatebenefratelli Sacco

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