World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
99
Citations
45017
World Ranking
739
National Ranking
420

Medicine

D-Index
99
Citations
45021
World Ranking
8472
National Ranking
4375

Overview

Gene M. Shearer is affiliated with the National Institutes of Health in the United States. Their research spans multiple areas within biological sciences, particularly focusing on biochemistry, genetics, and molecular biology, as well as agricultural and biological sciences.

The scientist's publications include topics centered around genetic engineering, neurodevelopmental disorders, and plant science. The main areas of study identifiable in their work are:

  • Biochemistry, Genetics and Molecular Biology
  • Agricultural and Biological Sciences

Subfields within these broader categories include:

  • Molecular Biology
  • Genetics
  • Plant Science

The core topics explored in their research are:

  • CRISPR and Genetic Engineering
  • Genetics and Neurodevelopmental Disorders
  • GABA and Rice Research

A notable recent publication is titled "WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication", published in 2020 through UNC Libraries. This work contributes to molecular biology and virology literature.

Gene M. Shearer has collaborated frequently with several researchers, including:

  • Dale M. Walker
  • Adriana E. Kajon
  • Salina Torres
  • Meghan M. Carter
  • Consuelo L. McCash

The scientist's body of work is cataloged primarily in venues such as:

  • UNC Libraries

Best Publications

  • Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS

    Robert C. Gallo;Syed Z. Salahuddin;Mikulas Popovic;Gene M. Shearer

  • T Lymphocyte-Directed Gene Therapy for ADA− SCID: Initial Trial Results After 4 Years

    R. Michael Blaese;Kenneth W. Culver;A. Dusty Miller;Charles S. Carter

  • A TH1→TH2 switch is a critical step in the etiology of HIV infection

    Mario Clerici;Gene M. Shearer

  • Modulation of Inflammation and Immunity by Cyclic AMP

    H R Bourne;L M Lichtenstein;K L Melmon;C S Henney

  • ADMINISTRATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE, AN INHIBITOR OF HTLV-III/LAV REPLICATION, TO PATIENTS WITH AIDS OR AIDS-RELATED COMPLEX

    Robert Yarchoan;Kent J. Weinhold;H. Kim Lyerly;Edward Gelmann

  • Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases.

    Daniel R. Lucey;Mario Clerici;Gene M. Shearer

  • Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging.

    M Clerici;N I Stocks;R A Zajac;R N Boswell

  • The Th1–Th2 hypothesis of HIV infection: new insights

    Mario Clerici;Gene M. Shearer

  • Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

    G. M. Shearer

  • Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection.

    Alan Sher;Ricardo T. Gazzinelli;Isabelle P. Oswald;Mario Clerici

  • Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts

    R. Kiessling;R. Kiessling;Paula S. Hochman;O. Haller;G. M. Shearer

  • Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals.

    Mario Clerici;Frances T. Hakim;David J. Venzon;Stephen Blatt

  • Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex.

    Gene M. Shearer;Terry G. Rehn;Carol A. Garbarino

  • Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses.

    S Shaw;A H Johnson;G M Shearer

  • Cell-Mediated Immune Response to Human Immunodeficiency Virus (HIV) Type 1 in Seronegative Homosexual Men with Recent Sexual Exposure to HIV-1

    Mario Clerici;Janis V. Giorgi;Janis V. Giorgi;Janis V. Giorgi;Chen Cheng Chou;Vaheideh K. Gudeman;Vaheideh K. Gudeman;Vaheideh K. Gudeman

  • Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

    Mario Clerici;Daniel R. Lucey;Jay A. Berzofsky;Ligia A. Pinto

  • Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.

    Mario Clerici;Thomas A. Wynn;Jay A. Berzofsky;Stephen P. Blatt

  • Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients

    Jan Andersson;Adriano Boasso;Jakob Nilsson;Rui Zhang

  • HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.

    Jakob Nilsson;Adriano Boasso;Paula Andrea Velilla;Rui Zhang

  • Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels

    Jianhui Zhu;Arshed A Quyyumi;James E Norman;Gyorgy Csako

Frequent Co-Authors

Mario Clerici
Mario Clerici University of Milan
Claire A. Chougnet
Claire A. Chougnet Cincinnati Children's Hospital Medical Center
Jay A. Berzofsky
Jay A. Berzofsky National Institutes of Health
Ligia A. Pinto
Ligia A. Pinto Leidos (United States)
Alan L. Landay
Alan L. Landay The University of Texas Medical Branch at Galveston
Harold A. Kessler
Harold A. Kessler Rush University Medical Center
Matthew J. Dolan
Matthew J. Dolan San Antonio Military Medical Center
Genoveffa Franchini
Genoveffa Franchini National Institutes of Health
David Venzon
David Venzon National Institutes of Health
Dietmar Fuchs
Dietmar Fuchs Innsbruck Medical University

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