World's Best Scientists 2026 revealed!

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Immunology

D-Index
82
Citations
20620
World Ranking
1527
National Ranking
764

Medicine

D-Index
82
Citations
20621
World Ranking
16299
National Ranking
8195

Overview

Genoveffa Franchini is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on immunology and microbiology, with a significant number of publications contributing to the fields of medicine and infectious diseases.

The scientist's work covers several specialized subfields including immunology, virology, agronomy and crop science, infectious diseases, and epidemiology. Their research addresses a range of topics such as HIV research and treatment, immune cell function and interaction, T-cell and retrovirus studies, animal disease management and epidemiology, vector-borne animal diseases, immune responses and vaccinations, as well as immunotherapy and immune responses.

Franchini has published extensively in various scientific journals, with frequent contributions to the following publication venues:

  • Nature Communications
  • PLoS Pathogens
  • Retrovirology
  • Journal of Virology
  • Nature Microbiology

Among their recent papers are:

  • "Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates," published in 2021 in iScience
  • "The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination," published in 2021 in Nature Immunology
  • "The V2 loop of HIV gp120 delivers costimulatory signals to CD4+T cells through Integrin α4β7and promotes cellular activation and infection," published in 2020 in Proceedings of the National Academy of Sciences
  • "NK cells and monocytes modulate primary HTLV-1 infection," published in 2022 in PLoS Pathogens
  • "Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition," published in 2020 in PLoS Pathogens

Genoveffa Franchini collaborates frequently with several researchers, including:

  • Massimiliano Bissa
  • Mohammad Arif Rahman
  • Isabela Silva de Castro
  • Melvin N. Doster
  • Luca Schifanella

Best Publications

  • Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

    Thi-Sau Migone;Jian-Xin Lin;Anna Cereseto;James C. Mulloy

  • Smallpox vaccine–induced antibodies are necessary and sufficient for protection against monkeypox virus

    Yvette Edghill-Smith;Hana Golding;Jody Manischewitz;Lisa R King

  • Cloning and characterization of different human sequences related to the onc gene (v-myc) of avian myelocytomatosis virus (MC29).

    R Dalla-Favera;E P Gelmann;S Martinotti;G Franchini

  • Molecular Biology of Human T-Lymphotropic Retroviruses

    Flossie Wong-Staal;Lee Ratner;George Shaw;Beatrice Hahn

  • HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.

    Jakob Nilsson;Adriano Boasso;Paula Andrea Velilla;Rui Zhang

  • Highly effective treatment of acquired immunodeficiency syndrome-related lymphoma with dose-adjusted EPOCH: impact of antiretroviral therapy suspension and tumor biology

    Richard F. Little;Stefania Pittaluga;Nicole Grant;Seth M. Steinberg

  • Superior T memory stem cell persistence supports long-lived T cell memory

    Enrico Lugli;Maria H. Dominguez;Luca Gattinoni;Pratip K. Chattopadhyay

  • Identification of the fusion peptide of primate immunodeficiency viruses.

    Marnix L. Bosch;Patricia L. Earl;Kathleen Fargnoli;Silvia Picciafuoco

  • Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins.

    Shigeki Takemoto;James C. Mulloy;Anna Cereseto;Thi-Sao Migone

  • ALVAC-SIV-gag-pol-env-Based Vaccination and Macaque Major Histocompatibility Complex Class I (A*01) Delay Simian Immunodeficiency Virus SIVmac-Induced Immunodeficiency

    R. Pal;D. Venzon;N. L. Letvin;S. Santra

  • Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses

    Igor M. Belyakov;Patricia Earl;Amiran Dzutsev;Vladimir A. Kuznetsov

  • T Cell Receptor Recognition Motifs Govern Immune Escape Patterns in Acute SIV Infection

    David A. Price;Sadie M. West;Michael R. Betts;Laura E. Ruff

  • IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates.

    Terry J. Fry;Marcin Moniuszko;Stephen Creekmore;Susan J. Donohue

  • Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques.

    Igor M. Belyakov;Zdenek Hel;Brian Kelsall;Vladimir A. Kuznetsov

  • Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I.

    I J Koralnik;A Gessain;M E Klotman;A Lo Monico

  • Genomic Evolution, Patterns of Global Dissemination, and Interspecies Transmission of Human and Simian T-cell Leukemia/Lymphotropic Viruses

    Jill Pecon Slattery;Genoveffa Franchini;Antoine Gessain

  • Complete nucleotide sequence of a highly divergent human T-cell leukemia (lymphotropic) virus type I (HTLV-I) variant from melanesia: genetic and phylogenetic relationship to HTLV-I strains from other geographical regions.

    A Gessain;E Boeri;R Yanagihara;R Gallo

  • The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.

    Naohiko Hattori;Frank Michaels;Kathleen Fargnoli;Luisa Marcon

  • HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication.

    Christophe Nicot;Christophe Nicot;Miroslav Dundr;Julie M Johnson;Jake R Fullen

  • Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses.

    Zdenek Hel;Janos Nacsa;Elzbieta Tryniszewska;Wen-Po Tsai

  • Human T-Cell Lymphotropic/Leukemia Virus Type 1 Tax Abrogates p53-Induced Cell Cycle Arrest and Apoptosis through Its CREB/ATF Functional Domain

    J. C. Mulloy;T. Kislyakova;A. Cereseto;L. Casareto

  • Viremia control following antiretroviral treatment and therapeutic immunization during primary SIV251 infection of macaques.

    Zdenek Hel;David Venzon;Monita Poudyal;Wen Po Tsai

  • SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

    Constantinos Petrovas;David A. Price;David A. Price;Joseph Mattapallil;David R. Ambrozak

Frequent Co-Authors

David Venzon
David Venzon National Institutes of Health
Robert C. Gallo
Robert C. Gallo University of South Florida
Marjorie Robert-Guroff
Marjorie Robert-Guroff National Institutes of Health
Phillip D. Markham
Phillip D. Markham Northrop Grumman (United States)
David C. Montefiori
David C. Montefiori Duke University
Christophe Nicot
Christophe Nicot University of Kansas
George N. Pavlakis
George N. Pavlakis Emory University
Ranajit Pal
Ranajit Pal Advanced Bioscience Laboratories (United States)
Gene M. Shearer
Gene M. Shearer National Institutes of Health
Barbara K. Felber
Barbara K. Felber National Institutes of Health

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