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D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
6613
World Ranking
18995
National Ranking
7755

Overview

Christophe Nicot is affiliated with the University of Kansas in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, medicine, and immunology and microbiology.

Their research spans multiple subfields including molecular biology, immunology, oncology, cancer research, and ecology, evolution, behavior, and systematics. The primary topics covered in their work include T-cell and retrovirus studies, vector-borne animal diseases, circular RNAs in diseases, animal disease management and epidemiology, PARP inhibition in cancer therapy, cancer-related molecular mechanisms research, and ubiquitin and proteasome pathways.

Christophe Nicot has frequently published in several scientific venues, with twelve publications in Molecular Cancer, two in Cytokine & Growth Factor Reviews, two in Drug Resistance Updates, two in Viruses, and one in Pathogens.

Frequent collaborators include Marcia Bellon, Hong Zhang, Liwu Fu, Yushi Li, and Gang Che.

Recent papers authored by Christophe Nicot include:

  • Clinical significance of FBXW7 loss of function in human cancers, 2022, Molecular Cancer
  • Targeting Pim kinases in hematological cancers: molecular and clinical review, 2023, Molecular Cancer
  • NCAPG promotes the oncogenesis and progression of non-small cell lung cancer cells through upregulating LGALS1 expression, 2022, Molecular Cancer
  • Insights into IL-6/JAK/STAT3 signaling in the tumor microenvironment: Implications for cancer therapy, 2025, Cytokine & Growth Factor Reviews
  • Loss of FBXW7-mediated degradation of BRAF elicits resistance to BET inhibitors in adult T cell leukemia cells, 2020, Molecular Cancer

Best Publications

  • FBXW7: a critical tumor suppressor of human cancers.

    Chien-Hung Yeh;Marcia Bellon;Christophe Nicot

  • HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication.

    Christophe Nicot;Christophe Nicot;Miroslav Dundr;Julie M Johnson;Jake R Fullen

  • An Exposed KID-Like Domain in Human T-Cell Lymphotropic Virus Type 1 Tax Is Responsible for the Recruitment of Coactivators CBP/p300

    Robert Harrod;Yong Tang;Christophe Nicot;Hsieng S. Lu

  • Human T-Cell Lymphotropic/Leukemia Virus Type 1 Tax Abrogates p53-Induced Cell Cycle Arrest and Apoptosis through Its CREB/ATF Functional Domain

    J. C. Mulloy;T. Kislyakova;A. Cereseto;L. Casareto

  • Deregulation of microRNA involved in hematopoiesis and the immune response in HTLV-I adult T-cell leukemia

    Marcia Bellon;Yves Lepelletier;Olivier Hermine;Christophe Nicot

  • Free Major Histocompatibility Complex Class I Heavy Chain Is Preferentially Targeted for Degradation by Human T-Cell Leukemia/Lymphotropic Virus Type 1 p12I Protein

    Julie M. Johnson;Christophe Nicot;Jake Fullen;Vincenzo Ciminale

  • Bcl-XL is up-regulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples

    Christophe Nicot;Renaud Mahieux;Shigeki Takemoto;Genoveffa Franchini

  • HTLV-1 p12I protein enhances STAT5 activation and decreases the interleukin-2 requirement for proliferation of primary human peripheral blood mononuclear cells

    Christophe Nicot;James C. Mulloy;Maria G. Ferrari;Julie M. Johnson

  • Clinical significance of microRNAs in chronic and acute human leukemia

    Chien-Hung Yeh;Ramona Moles;Christophe Nicot

  • Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.

    Abhik Datta;Marcia Bellon;Uma Sinha-Datta;Ali Bazarbachi

  • Transcriptional activation of hTERT through the NF-κB pathway in HTLV-I-transformed cells

    Uma Sinha-Datta;Izumi Horikawa;Eriko Michishita;Abhik Datta

  • Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage.

    Renaud Mahieux;Cynthia Pise-Masison;Antoine Gessain;John. N. Brady

  • Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions

    Christophe Nicot;Robert L Harrod;Vincenzo Ciminale;Genoveffa Franchini

  • Current views in HTLV-I-associated adult T-cell leukemia/lymphoma.

    Christophe Nicot

  • Regulation of Telomerase and Telomeres: Human Tumor Viruses Take Control

    Marcia Bellon;Christophe Nicot

  • Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1―associated adult T-cell leukemia

    Joanna Pancewicz;John M. Taylor;Abhik Datta;Hicham H. Baydoun

  • Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits.

    Valerio W. Valeri;Anna Hryniewicz;Vibeke Andresen;Kathy Jones

  • Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection

    Marcia Bellon;Christophe Nicot

  • Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.

    Marcia Bellon;Abhik Datta;Megan Brown;Jean-Francois Pouliquen

  • Human T-cell lymphotropic virus oncoprotein Tax represses TGF-β1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis

    Bertrand Arnulf;Aude Villemain;Aude Villemain;Christophe Nicot;Christophe Nicot;Elodie Mordelet;Elodie Mordelet

Frequent Co-Authors

Genoveffa Franchini
Genoveffa Franchini National Institutes of Health
Renaud Mahieux
Renaud Mahieux École Normale Supérieure de Lyon
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Olivier Hermine
Olivier Hermine Necker-Enfants Malades Hospital
Ali Bazarbachi
Ali Bazarbachi American University of Beirut
Antoine Gessain
Antoine Gessain Institut Pasteur
John N. Brady
John N. Brady National Institutes of Health
Miroslav Dundr
Miroslav Dundr Rosalind Franklin University of Medicine and Science
William W. Hall
William W. Hall University College Dublin
James C. Mulloy
James C. Mulloy Cincinnati Children's Hospital Medical Center

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