D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 82 Citations 23,959 228 World Ranking 8678 National Ranking 4700

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Enzyme
  • Inflammation

Bruce N. Cronstein spends much of his time researching Adenosine, Pharmacology, Adenosine receptor, Internal medicine and Endocrinology. His Adenosine study combines topics from a wide range of disciplines, such as Adenosine A3 receptor, Inflammation, Adenosine A1 receptor, Receptor and Purinergic signalling. Bruce N. Cronstein interconnects Methotrexate, Immunology, Monocyte, Adenosine deaminase and In vivo in the investigation of issues within Pharmacology.

His Methotrexate research integrates issues from Arthritis, Rheumatoid arthritis and Mechanism of action. His Adenosine receptor course of study focuses on N-Formylmethionine leucyl-phenylalanine and Cell migration, Pertussis toxin and Signal transduction. His study looks at the intersection of Endocrinology and topics like Proinflammatory cytokine with TSG-6, Serine protease, Plasmin, Protease and Plasminogen activator.

His most cited work include:

  • Adenosine receptors: therapeutic aspects for inflammatory and immune diseases (825 citations)
  • Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation (784 citations)
  • Adenosine: an endogenous regulator of innate immunity (711 citations)

What are the main themes of his work throughout his whole career to date?

Bruce N. Cronstein mostly deals with Adenosine, Internal medicine, Endocrinology, Pharmacology and Adenosine receptor. His biological study spans a wide range of topics, including Adenosine A3 receptor, Receptor, Purinergic signalling, Cell biology and Adenosine A2A receptor. His research in Adenosine A3 receptor intersects with topics in Adenosine A2B receptor and Adenosine A1 receptor.

His Endocrinology research is multidisciplinary, incorporating elements of Agonist, Osteoclast and Receptor antagonist. As a part of the same scientific family, Bruce N. Cronstein mostly works in the field of Pharmacology, focusing on Methotrexate and, on occasion, Rheumatoid arthritis. His Adenosine receptor research is multidisciplinary, relying on both Wound healing and Fibrosis.

He most often published in these fields:

  • Adenosine (44.27%)
  • Internal medicine (32.17%)
  • Endocrinology (28.03%)

What were the highlights of his more recent work (between 2017-2021)?

  • Adenosine (44.27%)
  • Biomedical engineering (4.46%)
  • Cell biology (17.52%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Adenosine, Biomedical engineering, Cell biology, Dipyridamole and Adenosine A2A receptor. His Adenosine research incorporates elements of Receptor, Cartilage, Adenosine receptor and Pharmacology. The study incorporates disciplines such as Fibrosis, Osteolysis and Sudden death in addition to Receptor.

His Adenosine receptor study incorporates themes from Reactive oxygen species and Homeostasis. His research in Biomedical engineering tackles topics such as Regeneration which are related to areas like In vivo. Bruce N. Cronstein has researched Cell biology in several fields, including Angiogenesis, Plasmin, Osteoblast, Chondrocyte and Tissue plasminogen activator.

Between 2017 and 2021, his most popular works were:

  • Methotrexate mechanism in treatment of rheumatoid arthritis. (59 citations)
  • Methotrexate and its mechanisms of action in inflammatory arthritis. (41 citations)
  • Effects of Acute Colchicine Administration Prior to Percutaneous Coronary Intervention: COLCHICINE-PCI Randomized Trial (30 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Enzyme
  • Cancer

His primary areas of investigation include Adenosine, Cell biology, Receptor, Adenosine receptor and Osteoclast. His studies in Adenosine integrate themes in fields like Methotrexate, Rheumatoid arthritis and Pharmacology. His Pharmacology study combines topics in areas such as Cytokine and Toxicity.

His Cell biology research incorporates themes from Acquired immune system, Immune system, Adenosine A2A receptor and Purine. His Receptor research includes themes of Biophysics and In vivo. His work carried out in the field of Adenosine receptor brings together such families of science as Small molecule and Nucleoside.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

György Haskó;Joel Linden;Bruce Cronstein;Pál Pacher.
Nature Reviews Drug Discovery (2006)

1127 Citations

Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation

M.J.L. Bours;E.L.R. Swennen;F. Di Virgilio;B.N. Cronstein.
Pharmacology & Therapeutics (2006)

1064 Citations

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1.

Cronstein Bn;Kimmel Sc;Levin Ri;Martiniuk F.
Proceedings of the National Academy of Sciences of the United States of America (1992)

968 Citations

Adenosine: an endogenous regulator of innate immunity

György Haskó;György Haskó;Bruce N. Cronstein.
Trends in Immunology (2004)

920 Citations

Adenosine, an endogenous anti-inflammatory agent

B. N. Cronstein.
Journal of Applied Physiology (1994)

800 Citations

The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.

Bruce N. Cronstein;Dwight Naime;Edward Ostad.
Journal of Clinical Investigation (1993)

769 Citations

Low-Dose Methotrexate: A Mainstay in the Treatment of Rheumatoid Arthritis

Bruce N. Cronstein.
Pharmacological Reviews (2005)

650 Citations

Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.

B N Cronstein;S B Kramer;G Weissmann;R Hirschhorn.
Journal of Experimental Medicine (1983)

549 Citations

Adenosine: An Endogenous Inhibitor of Neutrophil-Mediated Injury to Endothelial Cells

B N Cronstein;R I Levin;J Belanoff;G Weissmann.
Journal of Clinical Investigation (1986)

525 Citations

Molecular action of methotrexate in inflammatory diseases

Edwin S L Chan;Bruce N Cronstein.
Arthritis Research & Therapy (2002)

491 Citations

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