Bruce N. Cronstein spends much of his time researching Adenosine, Pharmacology, Adenosine receptor, Internal medicine and Endocrinology. His Adenosine study combines topics from a wide range of disciplines, such as Adenosine A3 receptor, Inflammation, Adenosine A1 receptor, Receptor and Purinergic signalling. Bruce N. Cronstein interconnects Methotrexate, Immunology, Monocyte, Adenosine deaminase and In vivo in the investigation of issues within Pharmacology.
His Methotrexate research integrates issues from Arthritis, Rheumatoid arthritis and Mechanism of action. His Adenosine receptor course of study focuses on N-Formylmethionine leucyl-phenylalanine and Cell migration, Pertussis toxin and Signal transduction. His study looks at the intersection of Endocrinology and topics like Proinflammatory cytokine with TSG-6, Serine protease, Plasmin, Protease and Plasminogen activator.
Bruce N. Cronstein mostly deals with Adenosine, Internal medicine, Endocrinology, Pharmacology and Adenosine receptor. His biological study spans a wide range of topics, including Adenosine A3 receptor, Receptor, Purinergic signalling, Cell biology and Adenosine A2A receptor. His research in Adenosine A3 receptor intersects with topics in Adenosine A2B receptor and Adenosine A1 receptor.
His Endocrinology research is multidisciplinary, incorporating elements of Agonist, Osteoclast and Receptor antagonist. As a part of the same scientific family, Bruce N. Cronstein mostly works in the field of Pharmacology, focusing on Methotrexate and, on occasion, Rheumatoid arthritis. His Adenosine receptor research is multidisciplinary, relying on both Wound healing and Fibrosis.
His primary areas of study are Adenosine, Biomedical engineering, Cell biology, Dipyridamole and Adenosine A2A receptor. His Adenosine research incorporates elements of Receptor, Cartilage, Adenosine receptor and Pharmacology. The study incorporates disciplines such as Fibrosis, Osteolysis and Sudden death in addition to Receptor.
His Adenosine receptor study incorporates themes from Reactive oxygen species and Homeostasis. His research in Biomedical engineering tackles topics such as Regeneration which are related to areas like In vivo. Bruce N. Cronstein has researched Cell biology in several fields, including Angiogenesis, Plasmin, Osteoblast, Chondrocyte and Tissue plasminogen activator.
His primary areas of investigation include Adenosine, Cell biology, Receptor, Adenosine receptor and Osteoclast. His studies in Adenosine integrate themes in fields like Methotrexate, Rheumatoid arthritis and Pharmacology. His Pharmacology study combines topics in areas such as Cytokine and Toxicity.
His Cell biology research incorporates themes from Acquired immune system, Immune system, Adenosine A2A receptor and Purine. His Receptor research includes themes of Biophysics and In vivo. His work carried out in the field of Adenosine receptor brings together such families of science as Small molecule and Nucleoside.
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Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
György Haskó;Joel Linden;Bruce Cronstein;Pál Pacher.
Nature Reviews Drug Discovery (2006)
Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
M.J.L. Bours;E.L.R. Swennen;F. Di Virgilio;B.N. Cronstein.
Pharmacology & Therapeutics (2006)
A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1.
Cronstein Bn;Kimmel Sc;Levin Ri;Martiniuk F.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Adenosine: an endogenous regulator of innate immunity
György Haskó;György Haskó;Bruce N. Cronstein.
Trends in Immunology (2004)
Adenosine, an endogenous anti-inflammatory agent
B. N. Cronstein.
Journal of Applied Physiology (1994)
The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.
Bruce N. Cronstein;Dwight Naime;Edward Ostad.
Journal of Clinical Investigation (1993)
Low-Dose Methotrexate: A Mainstay in the Treatment of Rheumatoid Arthritis
Bruce N. Cronstein.
Pharmacological Reviews (2005)
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
B N Cronstein;S B Kramer;G Weissmann;R Hirschhorn.
Journal of Experimental Medicine (1983)
Adenosine: An Endogenous Inhibitor of Neutrophil-Mediated Injury to Endothelial Cells
B N Cronstein;R I Levin;J Belanoff;G Weissmann.
Journal of Clinical Investigation (1986)
Molecular action of methotrexate in inflammatory diseases
Edwin S L Chan;Bruce N Cronstein.
Arthritis Research & Therapy (2002)
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