What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Tumor necrosis factor alpha, Molecular biology, Immunology, Interferon and Cytokine.
Jan Vilcek has included themes like Inflammation and Interleukin in his Tumor necrosis factor alpha study.
His studies in Molecular biology integrate themes in fields like Cell culture, cDNA library, Gene expression, Interferon gamma and Antibody.
His study in Immunology is interdisciplinary in nature, drawing from both Cancer research, In vitro and Cell biology.
Jan Vilcek interconnects Specific activity, IRF1, Messenger RNA and Viral replication in the investigation of issues within Interferon.
The study incorporates disciplines such as Therapeutic strategy, Downregulation and upregulation and Recombinant Cytokines in addition to Cytokine.
His most cited work include:
- Immune response in mice that lack the interferon-gamma receptor. (1410 citations)
- Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. (1216 citations)
- Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. (754 citations)
What are the main themes of his work throughout his whole career to date?
Jan Vilcek mostly deals with Molecular biology, Interferon, Immunology, Tumor necrosis factor alpha and Virology.
He has researched Molecular biology in several fields, including Recombinant DNA, Interferon gamma, Antigen and Antibody, Monoclonal antibody.
His studies deal with areas such as Cell culture, Cycloheximide, Biochemistry, Virus and Messenger RNA as well as Interferon.
His Cell culture research is multidisciplinary, incorporating elements of Concanavalin A, Receptor, Cell biology and Cytotoxicity.
His Immunology research includes elements of In vivo and Pathology.
His work in Tumor necrosis factor alpha addresses subjects such as Interleukin, which are connected to disciplines such as Interleukin 6.
He most often published in these fields:
- Molecular biology (40.55%)
- Interferon (35.62%)
- Immunology (27.95%)
What were the highlights of his more recent work (between 2000-2021)?
- Immunology (27.95%)
- Anti tnf alpha (10.68%)
- Tumor necrosis factor alpha (23.01%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Immunology, Anti tnf alpha, Tumor necrosis factor alpha, Virology and Molecular biology.
His work in Immunology is not limited to one particular discipline; it also encompasses Crohn's disease.
In his study, Interleukin is strongly linked to Cancer research, which falls under the umbrella field of Tumor necrosis factor alpha.
His Molecular biology research incorporates themes from Cell culture, Transfection and Antibody.
His Antibody study integrates concerns from other disciplines, such as Polynucleotide and Recombinant DNA.
His Cytokine research integrates issues from Growth factor and Cell biology.
Between 2000 and 2021, his most popular works were:
- Historical review: Cytokines as therapeutics and targets of therapeutics (154 citations)
- Cytokine-induced gene expression at the crossroads of innate immunity, inflammation and fertility: TSG-6 and PTX3/TSG-14. (125 citations)
- TSG‐14 transgenic mice have improved survival to endotoxemia and to CLP‐induced sepsis (121 citations)
In his most recent research, the most cited papers focused on:
Jan Vilcek spends much of his time researching Immunology, Tumor necrosis factor alpha, Anti tnf alpha, Molecular biology and Virology.
His work on Psoriasis and Pathogenesis as part of general Immunology research is often related to In patient, thus linking different fields of science.
His Tumor necrosis factor alpha research is multidisciplinary, relying on both Cancer research, Disease, Cytokine and PTX3.
His research in Cytokine focuses on subjects like Epidermal growth factor, which are connected to Cell biology.
His research in Molecular biology intersects with topics in Cell culture, Transfection, Inflammation, Kinase and p38 mitogen-activated protein kinases.
His study looks at the intersection of Virology and topics like Recombinant DNA with Antibody, Specific antibody and Anti tnf α.
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