2016 - Fellow, National Academy of Inventors
1997 - Fellow of the American Association for the Advancement of Science (AAAS)
His primary areas of investigation include Tumor necrosis factor alpha, Molecular biology, Immunology, Interferon and Cytokine. Jan Vilcek has included themes like Inflammation and Interleukin in his Tumor necrosis factor alpha study. His studies in Molecular biology integrate themes in fields like Cell culture, cDNA library, Gene expression, Interferon gamma and Antibody.
His study in Immunology is interdisciplinary in nature, drawing from both Cancer research, In vitro and Cell biology. Jan Vilcek interconnects Specific activity, IRF1, Messenger RNA and Viral replication in the investigation of issues within Interferon. The study incorporates disciplines such as Therapeutic strategy, Downregulation and upregulation and Recombinant Cytokines in addition to Cytokine.
Jan Vilcek mostly deals with Molecular biology, Interferon, Immunology, Tumor necrosis factor alpha and Virology. He has researched Molecular biology in several fields, including Recombinant DNA, Interferon gamma, Antigen and Antibody, Monoclonal antibody. His studies deal with areas such as Cell culture, Cycloheximide, Biochemistry, Virus and Messenger RNA as well as Interferon.
His Cell culture research is multidisciplinary, incorporating elements of Concanavalin A, Receptor, Cell biology and Cytotoxicity. His Immunology research includes elements of In vivo and Pathology. His work in Tumor necrosis factor alpha addresses subjects such as Interleukin, which are connected to disciplines such as Interleukin 6.
His primary areas of study are Immunology, Anti tnf alpha, Tumor necrosis factor alpha, Virology and Molecular biology. His work in Immunology is not limited to one particular discipline; it also encompasses Crohn's disease. In his study, Interleukin is strongly linked to Cancer research, which falls under the umbrella field of Tumor necrosis factor alpha.
His Molecular biology research incorporates themes from Cell culture, Transfection and Antibody. His Antibody study integrates concerns from other disciplines, such as Polynucleotide and Recombinant DNA. His Cytokine research integrates issues from Growth factor and Cell biology.
Jan Vilcek spends much of his time researching Immunology, Tumor necrosis factor alpha, Anti tnf alpha, Molecular biology and Virology. His work on Psoriasis and Pathogenesis as part of general Immunology research is often related to In patient, thus linking different fields of science. His Tumor necrosis factor alpha research is multidisciplinary, relying on both Cancer research, Disease, Cytokine and PTX3.
His research in Cytokine focuses on subjects like Epidermal growth factor, which are connected to Cell biology. His research in Molecular biology intersects with topics in Cell culture, Transfection, Inflammation, Kinase and p38 mitogen-activated protein kinases. His study looks at the intersection of Virology and topics like Recombinant DNA with Antibody, Specific antibody and Anti tnf α.
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Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.
Junming Le;J. Vilcek.
Laboratory Investigation (1987)
Immune response in mice that lack the interferon-gamma receptor.
Sui Huang;Wiljan Hendriks;Alana Althage;Silvio Hemmi.
New insights into the molecular mechanisms of its multiple actions
J. Vilcek;T. H. Lee.
Journal of Biological Chemistry (1991)
Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.
R. Kamijo;H. Harada;T. Matsuyama;Maarten C. Bosland.
Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
D M Knight;H Trinh;J Le;S Siegel.
Molecular Immunology (1993)
IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice.
D Aderka;J M Le;J Vilcek.
Journal of Immunology (1989)
Fibroblast Growth Enhancing Activity of Tumor Necrosis Factor and Its Relationship to Other Polypeptide Growth Factors
J Vilcek;V J Palombella;D Henriksen-DeStefano;C Swenson.
Journal of Experimental Medicine (1986)
Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation
Masayoshi Kohase;Dorothy Henriksen-DeStefano;Lester T. May;Jan Vilček.
Interleukin 6: a multifunctional cytokine regulating immune reactions and the acute phase protein response.
Junming Le;Jan Vilček.
Laboratory Investigation (1989)
Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells
M Tsujimoto;Y K Yip;J Vilcek.
Proceedings of the National Academy of Sciences of the United States of America (1985)
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