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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
38983
World Ranking
6107
National Ranking
115

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Michel Aguet is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research is positioned primarily in the fields of biochemistry, genetics, and molecular biology, with contributions also in medicine. The scientist's work spans several subfields including molecular biology, genetics, pathology and forensic medicine, and surgery.

The main research topics covered by Michel Aguet include:

  • Wnt/β-catenin signaling in development and cancer
  • Cancer-related gene regulation
  • Genetics and neurodevelopmental disorders
  • Genetic factors in colorectal cancer
  • Helicobacter pylori-related gastroenterology studies

Michel Aguet has contributed to multiple publications, including recent papers focused on gene regulation and signaling pathways in cancer. Notable recent papers are:

  • "TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex," 2020, published in eLife
  • "TBX3 acts as tissue-specific component of the Wnt/β-catenin enhanceosome," 2020, published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Epithelial Wnt secretion drives the progression of inflammation-induced colon carcinoma in murine model," 2021, published in iScience

The frequent co-authors collaborating with Michel Aguet include:

  • Konrad Basler
  • Andreas E. Moor
  • Dario Zimmerli
  • Costanza Borrelli
  • Amaia Jauregi-Miguel

The primary venues where Michel Aguet's recent work has been published consist of eLife, bioRxiv (Cold Spring Harbor Laboratory), and iScience.

Michel Aguet is recognized as a Member of the European Molecular Biology Organization (EMBO), a distinction that reflects their involvement in the broader scientific community.

Best Publications

  • Functional role of type I and type II interferons in antiviral defense.

    Ulrike Müller;Ulrich Steinhoff;Luiz F. L. Reis;Silvio Hemmi

  • Mice devoid of PrP are resistant to scrapie

    H. Büeler;A. Aguzzi;A. Sailer;R.-A. Greiner

  • Inducible gene targeting in mice

    Ralf Kühn;Frieder Schwenk;Michel Aguet;Klaus Rajewsky

  • Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

    Hansruedi Büeler;Marek Fischer;Yolande Lang;Yolande Lang;Horst Bluethmann;Horst Bluethmann

  • Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

    Marco A Meraz;Marco A Meraz;J.Michael White;Kathleen C.F Sheehan;Erika A Bach

  • Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

    Daniel H. Kaplan;Vijay Shankaran;Anand S. Dighe;Elisabeth Stockert

  • Immune response in mice that lack the interferon-gamma receptor.

    Sui Huang;Wiljan Hendriks;Alana Althage;Silvio Hemmi

  • Deficient T cell fate specification in mice with an induced inactivation of Notch1.

    Freddy Radtke;Anne Wilson;Gerlinde Stark;Michelle Bauer

  • Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA

    Olivier Cases;Isabelle Seif;Joseph Grimsby;Patricia Gaspar

  • THE IFN-GAMMA RECEPTOR: A PARADIGM FOR CYTOKINE RECEPTOR SIGNALING

    Erika A. Bach;Michel Aguet;Robert D. Schreiber

  • VEGF is required for growth and survival in neonatal mice

    Hans-Peter Gerber;Kenneth J. Hillan;Anne M. Ryan;Joe Kowalski

  • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

    Annapoorni Rangarajan;Annapoorni Rangarajan;Claudio Talora;Ryuhei Okuyama;Michael Nicolas

  • Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.

    Yi-Li Yang;L. F. L. Reis;J. Pavlovic;A. Aguzzi

  • A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

    Pierre Farmer;Pierre Farmer;Pierre Farmer;Hervé Bonnefoi;Pascale Anderle;David Cameron;David Cameron

  • Molecular cloning and expression of the human interferon-γ receptor

    Michel Aguet;Zlatko Dembić;Gilles Merlin

  • The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

    R Heuchel;F Radtke;O Georgiev;G Stark

  • The Orphan Receptor CRF2-4 Is an Essential Subunit of the Interleukin 10 Receptor

    Susan D. Spencer;Francesco Di Marco;Jeff Hooley;Sharon Pitts-Meek

  • Interferon gamma receptor deficient mice are resistant to endotoxic shock

    B. D. Car;V. M. Eng;B. Schnyder;L. Ozmen

  • Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide

    Ryutaro Kamijo;Junming Le;Deborah Shapiro;Edward A. Havell

  • The Transcription Factor Mtf-1 Is Essential for Basal and Heavy Metal-Induced Metallothionein-I Gene-Expression

    F. Radtke;R. Heuchel;O. Georgiev;G. Stark

Frequent Co-Authors

Charles Weissmann
Charles Weissmann University of Florida
Marek Fischer
Marek Fischer University of Zurich
Konrad Basler
Konrad Basler University of Zurich
Sui Huang
Sui Huang University of Calgary
Freddy Radtke
Freddy Radtke École Polytechnique Fédérale de Lausanne
Mauro Delorenzi
Mauro Delorenzi University of Lausanne
Adriano Aguzzi
Adriano Aguzzi University of Zurich
Rolf M. Zinkernagel
Rolf M. Zinkernagel University of Zurich
Horst Bluethmann
Horst Bluethmann Roche (Switzerland)
Jan Vilcek
Jan Vilcek New York University

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