What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Molecular biology, Immunology, Signal transduction, Cell biology and Receptor.
His Molecular biology research is multidisciplinary, incorporating elements of Cre recombinase and Interleukin-21 receptor, Interleukin-4 receptor.
His Immunology research is multidisciplinary, incorporating perspectives in Cytotoxic T cell and Virology.
His Signal transduction study integrates concerns from other disciplines, such as Cellular differentiation, Interferon, Transcription factor, Keratinocyte and EIF-2 kinase.
The Cell biology study combines topics in areas such as Repressor, Morphogenesis and Ankyrin repeat.
His work carried out in the field of Receptor brings together such families of science as Lineage markers, Antibody and T cell, Thymocyte.
His most cited work include:
- Functional role of type I and type II interferons in antiviral defense. (2095 citations)
- Mice devoid of PrP are resistant to scrapie (1803 citations)
- Inducible gene targeting in mice (1668 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Molecular biology, Receptor, Interferon, Cell biology and Immunology.
Michel Aguet interconnects Monoclonal antibody, Interleukin-21 receptor, Transfection and T cell in the investigation of issues within Molecular biology.
His Receptor research incorporates elements of Complementary DNA, Cell culture and Antibody.
His study with Interferon involves better knowledge in Virology.
His research in Cell biology intersects with topics in Gene and Cellular differentiation.
His work deals with themes such as Cytotoxic T cell and In vivo, which intersect with Immunology.
He most often published in these fields:
- Molecular biology (29.55%)
- Receptor (27.27%)
- Interferon (24.24%)
What were the highlights of his more recent work (between 2007-2020)?
- Wnt signaling pathway (9.85%)
- Cell biology (23.48%)
- Beta-catenin (5.30%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Wnt signaling pathway, Cell biology, Beta-catenin, Cancer research and BCL9.
His study in Catenin and Pygopus falls under the purview of Cell biology.
Beta-catenin is a subfield of Signal transduction that Michel Aguet explores.
The study incorporates disciplines such as Repressor and PAX6 in addition to Signal transduction.
His Cancer research research includes elements of Recombinant DNA, Immunology, ABL, Alpha interferon and Hairy cell leukemia.
The various areas that Michel Aguet examines in his Recombinant DNA study include Receptor, Downregulation and upregulation, Bone marrow and Tumor cells.
Between 2007 and 2020, his most popular works were:
- A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer (484 citations)
- Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis (135 citations)
- Bcl9/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem Cell Traits in Colon Epithelium and Adenocarcinomas (92 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Beta-catenin, Wnt signaling pathway, Cell biology, LRP5 and Stem cell.
His LRP5 research is multidisciplinary, relying on both Myogenesis, Skeletal muscle and LRP6.
His studies deal with areas such as Neural tube, Catenin, Cell adhesion and Cellular differentiation as well as LRP6.
By researching both Stem cell and Intestinal epithelium, he produces research that crosses academic boundaries.
His Cell signaling study frequently draws parallels with other fields, such as Pathology.
His studies in Pathology integrate themes in fields like Neoadjuvant therapy, Oncology, Chemotherapy, Stem cell marker and Carcinogenesis.
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