His primary areas of investigation include Immunology, Cancer research, Molecular biology, Signal transduction and Immune system. His research in the fields of Cytokine, Inflammation, Immunity and Acquired immune system overlaps with other disciplines such as Follicular dendritic cells. His Cytokine study integrates concerns from other disciplines, such as Myeloid and Cell biology.
The study incorporates disciplines such as Receptor and Tyrosine kinase 2 in addition to Cell biology. His research in Molecular biology intersects with topics in Genetics, Gene expression, Green fluorescent protein, Gene and Regulation of gene expression. His research investigates the link between Immune system and topics such as Interferon that cross with problems in Interferon regulatory factors and Hepatitis C virus.
The scientist’s investigation covers issues in Molecular biology, Cell biology, Immunology, Internal medicine and Cancer research. The various areas that Mathias Müller examines in his Molecular biology study include Complementary DNA, Biochemistry, Gene, Messenger RNA and Genetically modified mouse. His Cell biology research incorporates themes from Transcription factor and Cytokine.
His studies in Immune system, Inflammation, Immunity and Myeloid are all subfields of Immunology research. His work carried out in the field of Internal medicine brings together such families of science as Gastroenterology and Endocrinology. His research investigates the connection with Cancer research and areas like Tyrosine kinase 2 which intersect with concerns in TYK2 Kinase.
Mathias Müller spends much of his time researching Immunology, Cancer research, Cell biology, Signal transduction and STAT1. In his research, STAT5 is intimately related to Cellular differentiation, which falls under the overarching field of Immunology. The concepts of his Cancer research study are interwoven with issues in Tyrosine kinase 2, Kinase, Janus kinase, T cell and CD8.
His research in Tyrosine kinase 2 tackles topics such as Cytokine which are related to areas like Carcinogenesis. His Cell biology study focuses on Stem cell in particular. His study on STAT1 also encompasses disciplines like
Mathias Müller mostly deals with Immunology, Cancer research, Inflammation, Signal transduction and Immune system. His is involved in several facets of Immunology study, as is seen by his studies on Innate immune system and Cytokine. His Cancer research research includes elements of Tyrosine kinase 2, Janus kinase, T cell, Granzyme and Leukemia.
Mathias Müller works on Signal transduction which deals in particular with STAT1. He usually deals with Immune system and limits it to topics linked to Interferon and Proinflammatory cytokine and Pattern recognition receptor. Within one scientific family, he focuses on topics pertaining to Cell biology under Intestinal mucosa, and may sometimes address concerns connected to Transcription factor.
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Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis
Hans Neubauer;Ana Cumano;Mathias Müller;Hong Wu.
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction
Mathias Müller;James Briscoe;Carl Laxton;Dmitry Guschin.
The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response
Thomas Weichhart;Giuseppina Costantino;Marko Poglitsch;Margit Rosner.
The Yin and Yang of type I interferon activity in bacterial infection
Thomas Decker;Mathias Müller;Silvia Stockinger.
Nature Reviews Immunology (2005)
Selection of ventricular-like cardiomyocytes from ES cells in vitro
M. MÜller;B. K. Fleischmann;S. Selbert;G. J. Ji.
The FASEB Journal (2000)
IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA
Andreas Pichlmair;Caroline Lassnig;Carol-Ann Eberle;Maria W Górna.
Nature Immunology (2011)
Partial Impairment of Cytokine Responses in Tyk2-Deficient Mice
Marina Karaghiosoff;Hans Neubauer;Caroline Lassnig;Pavel Kovarik.
Complementation of a mutant cell line : central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways
Mathias Müller;Carl Laxton;James Briscoe;Chris Schindler.
The EMBO Journal (1993)
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.
Marina Karaghiosoff;Ralf Steinborn;Pavel Kovarik;Gernot Kriegshäuser.
Nature Immunology (2003)
IFNs and STATs in innate immunity to microorganisms.
Thomas Decker;Silvia Stockinger;Marina Karaghiosoff;Mathias Müller.
Journal of Clinical Investigation (2002)
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