What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Immunology, Cancer research, Molecular biology, Signal transduction and Immune system.
His research in the fields of Cytokine, Inflammation, Immunity and Acquired immune system overlaps with other disciplines such as Follicular dendritic cells.
His Cytokine study integrates concerns from other disciplines, such as Myeloid and Cell biology.
The study incorporates disciplines such as Receptor and Tyrosine kinase 2 in addition to Cell biology.
His research in Molecular biology intersects with topics in Genetics, Gene expression, Green fluorescent protein, Gene and Regulation of gene expression.
His research investigates the link between Immune system and topics such as Interferon that cross with problems in Interferon regulatory factors and Hepatitis C virus.
His most cited work include:
- Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis (723 citations)
- The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction (650 citations)
- The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response (571 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Molecular biology, Cell biology, Immunology, Internal medicine and Cancer research.
The various areas that Mathias Müller examines in his Molecular biology study include Complementary DNA, Biochemistry, Gene, Messenger RNA and Genetically modified mouse.
His Cell biology research incorporates themes from Transcription factor and Cytokine.
His studies in Immune system, Inflammation, Immunity and Myeloid are all subfields of Immunology research.
His work carried out in the field of Internal medicine brings together such families of science as Gastroenterology and Endocrinology.
His research investigates the connection with Cancer research and areas like Tyrosine kinase 2 which intersect with concerns in TYK2 Kinase.
He most often published in these fields:
- Molecular biology (22.54%)
- Cell biology (19.43%)
- Immunology (19.43%)
What were the highlights of his more recent work (between 2012-2021)?
- Immunology (19.43%)
- Cancer research (12.69%)
- Cell biology (19.43%)
In recent papers he was focusing on the following fields of study:
Mathias Müller spends much of his time researching Immunology, Cancer research, Cell biology, Signal transduction and STAT1.
In his research, STAT5 is intimately related to Cellular differentiation, which falls under the overarching field of Immunology.
The concepts of his Cancer research study are interwoven with issues in Tyrosine kinase 2, Kinase, Janus kinase, T cell and CD8.
His research in Tyrosine kinase 2 tackles topics such as Cytokine which are related to areas like Carcinogenesis.
His Cell biology study focuses on Stem cell in particular.
His study on STAT1 also encompasses disciplines like
- Transcription factor which intersects with area such as Molecular biology,
- stat most often made with reference to STAT protein,
- STAT2 which intersects with area such as Interferon regulatory factors.
Between 2012 and 2021, his most popular works were:
- Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection (173 citations)
- The regulation of inflammation by interferons and their STATs (164 citations)
- CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response (151 citations)
In his most recent research, the most cited papers focused on:
Mathias Müller mostly deals with Immunology, Cancer research, Inflammation, Signal transduction and Immune system.
His is involved in several facets of Immunology study, as is seen by his studies on Innate immune system and Cytokine.
His Cancer research research includes elements of Tyrosine kinase 2, Janus kinase, T cell, Granzyme and Leukemia.
Mathias Müller works on Signal transduction which deals in particular with STAT1.
He usually deals with Immune system and limits it to topics linked to Interferon and Proinflammatory cytokine and Pattern recognition receptor.
Within one scientific family, he focuses on topics pertaining to Cell biology under Intestinal mucosa, and may sometimes address concerns connected to Transcription factor.
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