World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
11952
World Ranking
9371
National Ranking
285

Overview

De-Pei Liu is affiliated with the Peking Union Medical College Hospital in China and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields including Molecular Biology, Immunology, Epidemiology, Physiology, and Cardiology and Cardiovascular Medicine.

The scientist's publications focus on a range of contemporary biomedical topics. Some of the main areas covered include CRISPR and Genetic Engineering, Sirtuins and Resveratrol in Medicine, Atherosclerosis and Cardiovascular Diseases, Long-Term Effects of COVID-19, Cytomegalovirus and Herpesvirus Research, interferon and immune responses, and Circadian rhythm and melatonin.

Notable recent papers by De-Pei Liu include:

  • Short-Chain Enoyl-CoA Hydratase Mediates Histone Crotonylation and Contributes to Cardiac Homeostasis (2021, Circulation)
  • Comprehensive assessment of cellular senescence in the tumor microenvironment (2022, Briefings in Bioinformatics)
  • Targeting PDE4B (Phosphodiesterase-4 Subtype B) for Cardioprotection in Acute Myocardial Infarction via Neutrophils and Microcirculation (2022, Circulation Research)
  • The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation (2021, Pharmacological Research)
  • SIRT6 is an epigenetic repressor of thoracic aortic aneurysms via inhibiting inflammation and senescence (2023, Signal Transduction and Targeted Therapy)

The scientist collaborates frequently with several coauthors, including Hou-Zao Chen, De-Long Hao, Xiaoman Wang, Ziyu Wei, and Haojie Rao. These collaborations have contributed to the breadth and depth of Liu's research output.

De-Pei Liu's work has appeared regularly in several publication venues, among which Signal Transduction and Targeted Therapy, PubMed, and Chinese Medical Sciences Journal each feature three publications. Other venues include Circulation Research and Nature Communications.

Best Publications

  • Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

    Qing-jun Zhang;Zhao Wang;Hou-zao Chen;Shuang Zhou

  • Mitochondria, endothelial cell function, and vascular diseases.

    Xiaoqiang Tang;Yu-Xuan Luo;Hou-Zao Chen;De-Pei Liu

  • Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease

    Xiangfeng Lu;Laiyuan Wang;Laiyuan Wang;Shufeng Chen;Lin He

  • Paraoxonase gene polymorphisms, oxidative stress, and diseases

    Hong-Liang Li;De-Pei Liu;Chih-Chuan Liang

  • Repression of P66Shc Expression by SIRT1 Contributes to the Prevention of Hyperglycemia-Induced Endothelial Dysfunction

    Shuang Zhou;Hou-Zao Chen;Yan-zhen Wan;Qing-Jun Zhang

  • The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

    Qing Jun Zhang;Hou Zao Chen;Lin Wang;De Pei Liu

  • SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy.

    Xiaoqiang Tang;Xiao-Feng Chen;Nan-Yu Wang;Xiao-Man Wang

  • Oxidative stress in atrial fibrillation: an emerging role of NADPH oxidase.

    Ji-Youn Youn;Jun Zhang;Yixuan Zhang;Houzao Chen

  • SIRT1 Suppresses Activator Protein-1 Transcriptional Activity and Cyclooxygenase-2 Expression in Macrophages

    Ran Zhang;Hou-Zao Chen;Jin-Jing Liu;Yu-Yan Jia

  • Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm.

    Hou-Zao Chen;Fang Wang;Peng Gao;Jian-Fei Pei

  • Sirt4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity

    Yu-Xuan Luo;Xiaoqiang Tang;Xi-Zhou An;Xue-Min Xie

  • Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways.

    Hong Liang Li;Yue Huang;Chan Na Zhang;Guang Liu

  • SIRT1 Acts as a Modulator of Neointima Formation Following Vascular Injury in Mice

    Li Li;Hui-Na Zhang;Hou-Zao Chen;Peng Gao

  • MicroRNAs: key participants in gene regulatory networks

    Xi-Song Ke;Chang-Mei Liu;De-Pei Liu;Chih-Chuan Liang

  • Positive regulation of hepatic miR-122 expression by HNF4α

    Zhen-Ya Li;Yang Xi;Wen-Nan Zhu;Chao Zeng

  • Active Chromatin Hub of the Mouse α-Globin Locus Forms in a Transcription Factory of Clustered Housekeeping Genes

    Guo-Ling Zhou;Li Xin;Wei Song;Li-Jun Di

  • Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways

    Hong Liang Li;Ai Bing Wang;Yue Huang;De Pei Liu

  • Interferon regulatory factor 3 constrains IKKβ/NF-κB signaling to alleviate hepatic steatosis and insulin resistance

    Xin-An Wang;Ran Zhang;Zhi-Gang She;Xiao-Fei Zhang

  • Metagenomic profiling of the pro-inflammatory gut microbiota in ankylosing spondylitis.

    Chen Zhou;Hui Zhao;Xin-yue Xiao;Bei-di Chen

  • Both TALENs and CRISPR/Cas9 directly target the HBB IVS2–654 (C > T) mutation in β-thalassemia-derived iPSCs

    Peng Xu;Ying Tong;Xiu-zhen Liu;Ting-ting Wang

Frequent Co-Authors

Jiang He
Jiang He Tulane University
Hongliang Li
Hongliang Li Wuhan University
Dongfeng Gu
Dongfeng Gu Southern University of Science and Technology
Dabeeru C. Rao
Dabeeru C. Rao Washington University in St. Louis
Treva Rice
Treva Rice Washington University in St. Louis
Jian-Dong Huang
Jian-Dong Huang Chinese Academy of Sciences
Paul K. Whelton
Paul K. Whelton Tulane University
Kathryn S. E. Cheah
Kathryn S. E. Cheah University of Hong Kong
Peng Xu
Peng Xu Chinese Academy of Sciences
Donald L. Court
Donald L. Court National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing De-Pei Liu

Trending Scientists

Recently Published Articles