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D-Index & Metrics

Genetics

D-Index
57
Citations
15480
World Ranking
3384
National Ranking
1461

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Douglas R. Cavener is affiliated with Pennsylvania State University in the United States. Their research spans several disciplines, primarily within biochemistry, genetics, and molecular biology, as well as environmental science. Their work includes detailed investigations in molecular biology, ecology, genetics, cell biology, and areas related to policy and law in environmental management.

The main research topics covered by Cavener include wildlife ecology and conservation, endoplasmic reticulum stress and disease, genetic diversity and population structure, rangeland management and livestock ecology, animal ecology and behavior studies, CRISPR and genetic engineering, and pluripotent stem cells research.

Their scientific output encompasses papers published in notable venues such as Ecology and Evolution, Mammalian Biology, bioRxiv (Cold Spring Harbor Laboratory), PLoS Genetics, and the Journal of Neuroscience. Frequent publication venues indicate active contributions to Ecology and Evolution and Mammalian Biology.

Some recent published papers include:

  • Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice, 2020, PLoS Genetics
  • Genetic connectivity and population structure of African savanna elephants (Loxodonta africana) in Tanzania, 2020, Ecology and Evolution
  • Genetic evidence of population subdivision among Masai giraffes separated by the Gregory Rift Valley in Tanzania, 2023, Ecology and Evolution
  • Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy, 2021, Journal of Neuroscience
  • Using spot pattern recognition to examine population biology, evolutionary ecology, sociality, and movements of giraffes: a 70-year retrospective, 2022, Mammalian Biology

Cavener has collaborated frequently with several researchers, including George G. Lohay, Derek Lee, Monica L. Bond, Barbara C. McGrath, and Lan Wu-Cavener. These collaborations reflect an interdisciplinary approach bridging genetics, ecology, and behavior studies.

In 2014, Douglas R. Cavener was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells

    Francesca Fallarino;Ursula Grohmann;Sylvaine You;Barbara C. McGrath

  • Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates

    Douglas R. Cavener

  • Eukaryotic start and stop translation sites

    Douglas R. Cavener;Stuart C. Ray

  • The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas

    Peichuan Zhang;Barbara McGrath;Sheng'ai Li;Ami Frank

  • Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

    Tao Ma;Mimi A Trinh;Alyse J Wexler;Clarisse Bourbon;Clarisse Bourbon

  • Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.

    Hao Yuan Jiang;Sheree A. Wek;Barbara C. McGrath;Dan Lu

  • The GCN2 eIF2α Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice

    Peichuan Zhang;Peichuan Zhang;Barbara C. McGrath;Jamie Reinert;De Anne S. Olsen

  • Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses

    Hao Yuan Jiang;Sheree A. Wek;Barbara C. McGrath;Donalyn Scheuner

  • Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism

    Valérie Senée;Valérie Senée;Claude Chelala;Claude Chelala;Sabine Duchatelet;Sabine Duchatelet;Daorong Feng

  • Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex

    Shuzhen Hao;James W. Sharp;Catherine M. Ross-Inta;Brent J. McDaniel

  • Translational control and the unfolded protein response.

    Ronald C. Wek;Douglas R. Cavener

  • A Mammalian Homologue of GCN2 Protein Kinase Important for Translational Control by Phosphorylation of Eukaryotic Initiation Factor-2α

    Ruchira Sood;Amy C. Porter;De Anne Olsen;Douglas R. Cavener

  • GMC oxidoreductases: A newly defined family of homologous proteins with diverse catalytic activities☆

    Douglas R. Cavener

  • PERK EIF2AK3 control of pancreatic β cell differentiation and proliferation is required for postnatal glucose homeostasis

    Wei Zhang;Daorong Feng;Yulin Li;Kaori Iida

  • Analysis of the PvuII restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breast cancer and peripheral blood.

    Lauren Yaich;William D. Dupont;Douglas R. Cavener;Fritz F. Parl

  • PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

    E Bobrovnikova-Marjon;C Grigoriadou;D Pytel;F Zhang

  • The GCN2 eIF2α Kinase Regulates Fatty-Acid Homeostasis in the Liver during Deprivation of an Essential Amino Acid

    Feifan Guo;Douglas R. Cavener

  • Endoplasmic Reticulum Stress Response Mediated by the PERK-eIF2α-ATF4 Pathway Is Involved in Osteoblast Differentiation Induced by BMP2

    Atsushi Saito;Kimiko Ochiai;Shinichi Kondo;Kenji Tsumagari

  • PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation

    Ekaterina Bobrovnikova-Marjon;Georgia Hatzivassiliou;Christina Grigoriadou;Margarita Romero

  • Brain ischemia and reperfusion activates the eukaryotic initiation factor 2α kinase, PERK

    Rita Kumar;Salman Azam;Jonathan M. Sullivan;Cheri Owen

Frequent Co-Authors

Ronald C. Wek
Ronald C. Wek Indiana University
Scot R. Kimball
Scot R. Kimball Pennsylvania State University
Michael T. Clegg
Michael T. Clegg University of California, Irvine
Eric Klann
Eric Klann New York University
Leonard S. Jefferson
Leonard S. Jefferson Pennsylvania State University
Heather P. Harding
Heather P. Harding University of Cambridge
David Ron
David Ron University of Cambridge
Philippe Pierre
Philippe Pierre Aix-Marseille University
Carmine Vacca
Carmine Vacca University of Perugia
Thomas C. Kaufman
Thomas C. Kaufman Indiana University

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