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Heather P. Harding

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
66429
World Ranking
2489
National Ranking
176

Heather P. Harding publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Heather P. Harding sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 152 publications — 27th percentile

27% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Heather P. Harding D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Heather P. Harding sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 89 D-Index — 87th percentile

87% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Heather P. Harding is affiliated with the University of Cambridge in the United Kingdom and specializes in Biochemistry, Genetics, and Molecular Biology. Within this broad domain, their research focuses on molecular biology, cell biology, epidemiology, surgery, and genetics. The main topics explored in their work include endoplasmic reticulum stress and disease, RNA regulation and disease, RNA research and splicing, autophagy in disease and therapy, pancreatic function and diabetes, CRISPR and genetic engineering, as well as cancer, hypoxia, and metabolism.

They have published extensively, with a notable presence in journals such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Molecular Cell, The EMBO Journal, and EMBO Molecular Medicine. The majority of their papers are concentrated in the field of molecular biology and cell biology, reflecting a consistent research trajectory in these areas.

Key recent papers authored or co-authored by Heather P. Harding include:

  • "ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B" (2020, Molecular Cell)
  • "ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth" (2020, UNC Libraries)
  • "Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers" (2021, Cell Reports)
  • "The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells" (2023, The EMBO Journal)
  • "Higher-order phosphatase-substrate contacts terminate the integrated stress response" (2021, Nature Structural & Molecular Biology)

Throughout their career, Harding has collaborated frequently with several researchers, including David Ron, A. Ordóñez, Ginto George, Alisa Zyryanova, and Yahui Yan. These collaborations underline a network of research partnerships contributing to advancements in their areas of study.

Best Publications

  • Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

    Heather P. Harding;Yuhong Zhang;David Ron

  • An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

    Heather P. Harding;Yuhong Zhang;Huiquing Zeng;Isabel Novoa

  • Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

    Heather P Harding;Isabel Novoa;Yuhong Zhang;Huiqing Zeng

  • Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.

    Fumihiko Urano;Xiao Zhong Wang;Anne Bertolotti;Yuhong Zhang

  • Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

    Anne Bertolotti;Yuhong Zhang;Linda M. Hendershot;Linda M. Hendershot;Heather P. Harding

  • IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

    Marcella Calfon;Huiqing Zeng;Fumihiko Urano;Jeffery H Till

  • Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response

    Heather P Harding;Yuhong Zhang;Anne Bertolotti;Huiqing Zeng

  • CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

    Stefan J. Marciniak;Chi Y. Yun;Seiichi Oyadomari;Isabel Novoa

  • Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

    J. Nangalia;C.E. Massie;E.J. Baxter;F.L. Nice

  • A Selective Inhibitor of eIF2α Dephosphorylation Protects Cells from ER Stress

    Michael Boyce;Kevin F. Bryant;Céline Jousse;Kai Long

  • Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

    Isabel Novoa;Huiqing Zeng;Heather P. Harding;David Ron

  • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

    David H. Munn;Madhav D. Sharma;Babak Baban;Heather P. Harding

  • Diabetes Mellitus and Exocrine Pancreatic Dysfunction in Perk−/− Mice Reveals a Role for Translational Control in Secretory Cell Survival

    Heather P. Harding;Huiqing Zeng;Yuhong Zhang;Rivka Jungries

  • Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

    Phoebe D. Lu;Heather P. Harding;David Ron

  • Transcriptional and Translational Control in the Mammalian Unfolded Protein Response

    Heather P Harding;Marcella Calfon;Fumihiko Urano;Isabel Novoa

  • The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

    Bo Feng;Pin Mei Yao;Yankun Li;Cecilia M. Devlin

  • Targeting the unfolded protein response in disease

    Claudio Hetz;Eric Chevet;Heather P. Harding

  • Cloning of mammalian Ire1 reveals diversity in the ER stress responses.

    Xiao Zhong Wang;Heather P. Harding;Yuhong Zhang;Ethel M. Jolicoeur

  • Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

    Ker Yu;William Bayona;Caleb B. Kallen;Heather P. Harding

  • ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

    Meixia Bi;Christine Naczki;Marianne Koritzinsky;Diane Fels

Frequent Co-Authors

David Ron
David Ron University of Cambridge
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Mitchell A. Lazar
Mitchell A. Lazar University of Pennsylvania
Leopold Parts
Leopold Parts Wellcome Sanger Institute
Stephen O'Rahilly
Stephen O'Rahilly University of Cambridge
Fumihiko Urano
Fumihiko Urano Washington University in St. Louis
Brian Popko
Brian Popko Northwestern University
Wayne I. Lencer
Wayne I. Lencer Harvard University
Jonathan C. Kagan
Jonathan C. Kagan Boston Children's Hospital
Laurie H. Glimcher
Laurie H. Glimcher Harvard University

External Links

Personal website of Heather P. Harding

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Best Scientists Citing Heather P. Harding

Randal J. Kaufman

Randal J. Kaufman

Sanford Burnham Prebys Medical Discovery Institute

Publications: 197

Claudio Hetz

Claudio Hetz

University of Chile

Publications: 134

David Ron

David Ron

University of Cambridge

Publications: 115

Peter Walter

Peter Walter

University of California, San Francisco

Publications: 105

Ronald C. Wek

Ronald C. Wek

Indiana University

Publications: 91

Mitchell A. Lazar

Mitchell A. Lazar

University of Pennsylvania

Publications: 74

Kazutoshi Mori

Kazutoshi Mori

Kyoto University

Publications: 67

Afshin Samali

Afshin Samali

University of Galway

Publications: 65

Ira Tabas

Ira Tabas

Columbia University

Publications: 63

Alessandro M. Vannucchi

Alessandro M. Vannucchi

University of Florence

Publications: 61

Laurie H. Glimcher

Laurie H. Glimcher

Harvard University

Publications: 61

Takao Iwawaki

Takao Iwawaki

Kanazawa Medical University

Publications: 58

Kazunori Imaizumi

Kazunori Imaizumi

Hiroshima University

Publications: 57

Antonis E. Koromilas

Antonis E. Koromilas

McGill University

Publications: 57

Linda M. Hendershot

Linda M. Hendershot

St. Jude Children's Research Hospital

Publications: 57

Miriam Cnop

Miriam Cnop

Université Libre de Bruxelles

Publications: 56

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