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Leonard S. Jefferson

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
33832
World Ranking
1166
National Ranking
692

Medicine

D-Index
106
Citations
33796
World Ranking
6614
National Ranking
3508

Leonard S. Jefferson publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Leonard S. Jefferson sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 356 publications — 86th percentile

86% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Leonard S. Jefferson D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Leonard S. Jefferson sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 106 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leonard S. Jefferson is affiliated with Pennsylvania State University in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work has a particular focus on Molecular Biology and Cell Biology, with additional involvement in Pulmonary and Respiratory Medicine, Cellular and Molecular Neuroscience, and Biomedical Engineering.

The scientist's research interests revolve around several specialized topics, including:

  • PI3K/AKT/mTOR signaling in cancer
  • Muscle Physiology and Disorders
  • Protein Kinase Regulation and GTPase Signaling
  • Muscle metabolism and nutrition
  • Genetic Neurodegenerative Diseases
  • Muscle activation and electromyography studies
  • Fibroblast Growth Factor Research

Leonard S. Jefferson has contributed to multiple research publications, with recent notable papers that provide insights into protein synthesis regulation, signaling pathways, and metabolic processes. Significant papers include:

  • "A time course for markers of protein synthesis and degradation with hindlimb unloading and the accompanying anabolic resistance to refeeding," 2020, Journal of Applied Physiology
  • "Loss of 4E-BPs prevents the hindlimb immobilization-induced decrease in protein synthesis in skeletal muscle," 2022, Journal of Applied Physiology
  • "Glucagon-dependent suppression of mTORC1 is associated with upregulation of hepatic FGF21 mRNA translation," 2020, American Journal of Physiology-Endocrinology and Metabolism
  • "Convergence of signaling pathways in mediating actions of leucine and IGF-1 on mTORC1 in L6 myoblasts," 2022, American Journal of Physiology-Cell Physiology
  • "Glucose-Induced Activation of mTORC1 is Associated with Hexokinase2 Binding to Sestrins in HEK293T Cells," 2022, Journal of Nutrition

The primary venues for Leonard S. Jefferson's work include:

  • Journal of Applied Physiology
  • American Journal of Physiology-Endocrinology and Metabolism
  • American Journal of Physiology-Cell Physiology
  • Journal of Nutrition
  • Frontiers in Endocrinology

Collaborative research is a notable aspect of this scientist's career. Frequent co-authors include:

  • Scot R. Kimball
  • Paul A. Roberson
  • Jaclyn E. Welles
  • Gregory N. Kincheloe
  • Michael D. Dennis

Leonard S. Jefferson was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling.

    Douglas R. Bolster;Stephen J. Crozier;Scot R. Kimball;Leonard S. Jefferson

  • Leucine Stimulates Translation Initiation in Skeletal Muscle of Postabsorptive Rats via a Rapamycin-Sensitive Pathway

    Joshua C. Anthony;Fumiaki Yoshizawa;Tracy Gautsch Anthony;Thomas C. Vary

  • Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

    David A. Antonetti;Alistair J. Barber;Sarah K. Bronson;Willard M. Freeman

  • Signaling Pathways and Molecular Mechanisms through which Branched-Chain Amino Acids Mediate Translational Control of Protein Synthesis

    Scot R. Kimball;Leonard S. Jefferson

  • Signaling Pathways Involved in Translational Control of Protein Synthesis in Skeletal Muscle by Leucine

    Joshua C. Anthony;Tracy G. Anthony;Scot R. Kimball;Leonard S. Jefferson

  • Orally Administered Leucine Stimulates Protein Synthesis in Skeletal Muscle of Postabsorptive Rats in Association with Increased eIF4F Formation

    Joshua C. Anthony;Tracy Gautsch Anthony;Scot R. Kimball;Thomas C. Vary

  • The GCN2 eIF2α Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice

    Peichuan Zhang;Peichuan Zhang;Barbara C. McGrath;Jamie Reinert;De Anne S. Olsen

  • Oral Leucine Administration Stimulates Protein Synthesis in Rat Skeletal Muscle

    Stephen J. Crozier;Scot R. Kimball;Sans W. Emmert;Joshua C. Anthony

  • Regulation of protein synthesis in heart muscle. I. Effect of amino acid levels on protein synthesis.

    H.E. Morgan;D.C.N. Earl;A. Broadus;E.B. Wolpert

  • Role of Adenosine 3',5'-Monophosphate in the Effects of Insulin and Anti-insulin Serum on Liver Metabolism

    L. S. Jefferson;J. H. Exton;R. W. Butcher;Earl W. Sutherland

  • Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

    Scot R. Kimball;Lisa M. Shantz;Rick L. Horetsky;Leonard S. Jefferson

  • Dexamethasone Represses Signaling through the Mammalian Target of Rapamycin in Muscle Cells by Enhancing Expression of REDD1

    Hongmei Wang;Neil Kubica;Leif W. Ellisen;Leonard S. Jefferson

  • Invited Review: Role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise

    Scot R. Kimball;Peter A. Farrell;Leonard S. Jefferson

  • Influence of amino acid availability on protein turnover in perfused skeletal muscle.

    Jeanne B. Li;Leonard S. Jefferson

  • Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.

    Scot R. Kimball;Rick L. Horetsky;David Ron;Leonard S. Jefferson

  • 4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle.

    O. Jameel Shah;Joshua C. Anthony;Scot R. Kimball;Leonard S. Jefferson

  • Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle

    Douglas R. Bolster;Neil Kubica;Stephen J. Crozier;David L. Williamson

  • New functions for amino acids: effects on gene transcription and translation

    Scot R Kimball;Leonard S Jefferson

  • Role of Insulin in the Regulation of Protein Synthesis

    Leonard S. Jefferson

  • Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and insulin.

    Nabil A. Elshourbagy;Mark S. Boguski;Warren S. L. Liao;Leonard S. Jefferson

Frequent Co-Authors

Scot R. Kimball
Scot R. Kimball Pennsylvania State University
Charles H. Lang
Charles H. Lang Pennsylvania State University
Anthony E. Pegg
Anthony E. Pegg Pennsylvania State University
Allan Lipton
Allan Lipton Penn State Milton S. Hershey Medical Center
Douglas R. Cavener
Douglas R. Cavener Pennsylvania State University
Patrice Fort
Patrice Fort University of Michigan–Ann Arbor
Robert L. Matts
Robert L. Matts Oklahoma State University
Susan M. Hutson
Susan M. Hutson Virginia Tech
John C. Lawrence
John C. Lawrence University of Virginia
Yuguang Shi
Yuguang Shi The University of Texas Health Science Center at San Antonio

External Links

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Best Scientists Citing Leonard S. Jefferson

Charles H. Lang

Charles H. Lang

Pennsylvania State University

Publications: 126

Scot R. Kimball

Scot R. Kimball

Pennsylvania State University

Publications: 93

Christopher G. Proud

Christopher G. Proud

University of Adelaide

Publications: 81

Stuart M. Phillips

Stuart M. Phillips

McMaster University

Publications: 78

Guoyao Wu

Guoyao Wu

Texas A&M University

Publications: 67

Robert R. Wolfe

Robert R. Wolfe

University of Arkansas for Medical Sciences

Publications: 66

Blake B. Rasmussen

Blake B. Rasmussen

The University of Texas Medical Branch at Galveston

Publications: 59

Michael J. Rennie

Michael J. Rennie

University of Nottingham

Publications: 53

Elena Volpi

Elena Volpi

The University of Texas Medical Branch at Galveston

Publications: 47

Anastasia Khvorova

Anastasia Khvorova

University of Massachusetts Chan Medical School

Publications: 45

Luc J. C. van Loon

Luc J. C. van Loon

Maastricht University

Publications: 43

Kenneth Smith

Kenneth Smith

University of Nottingham

Publications: 43

Benoit Viollet

Benoit Viollet

Institut Cochin

Publications: 40

Yves Boirie

Yves Boirie

University of Clermont Auvergne

Publications: 40

Yulong Yin

Yulong Yin

Chinese Academy of Sciences

Publications: 37

David Cameron-Smith

David Cameron-Smith

Agency for Science, Technology and Research

Publications: 34

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