His primary scientific interests are in Biochemistry, Amino acid, Asparagine synthetase, ATF4 and Molecular biology. His study in Biochemistry focuses on Asparagine, Hepatocyte, Gene, Serine and Cysteine. The study incorporates disciplines such as Membrane transport, Gene expression and Messenger RNA in addition to Amino acid.
His biological study spans a wide range of topics, including Signal transduction and Transcription Factor CHOP. Transcriptional regulation and CREB is closely connected to Endoplasmic reticulum in his research, which is encompassed under the umbrella topic of Molecular biology. His study focuses on the intersection of Transcription factor and fields such as Transcription with connections in the field of ATF3.
Michael S. Kilberg focuses on Biochemistry, Amino acid, Molecular biology, Asparagine synthetase and Cell biology. His Amino acid study incorporates themes from Endocrinology and Gene expression, Messenger RNA, Gene. Michael S. Kilberg interconnects Transcription factor, ATF4, Response element, RNA polymerase II and Transcription in the investigation of issues within Molecular biology.
His Transcription factor study combines topics from a wide range of disciplines, such as Unfolded protein response and Regulation of gene expression. His research in ATF4 intersects with topics in Signal transduction and Transcription Factor CHOP. His Asparagine synthetase research is multidisciplinary, incorporating elements of Cancer research, Endoplasmic reticulum, Transcriptional regulation and In vitro.
His primary areas of study are ATF4, Molecular biology, Cell biology, Activating Transcription Factor 4 and Asparagine. Michael S. Kilberg combines subjects such as Cancer research, Signal transduction and Activating transcription factor with his study of ATF4. His research integrates issues of Response element, RNA polymerase II, Transcription and Activating transcription factor 2 in his study of Molecular biology.
His studies in Cell biology integrate themes in fields like Inflammation, Downregulation and upregulation and Epigenetics. His study on Asparagine is covered under Biochemistry. His Asparagine synthetase study introduces a deeper knowledge of Amino acid.
Michael S. Kilberg spends much of his time researching ATF4, Unfolded protein response, Activating Transcription Factor 4, Molecular biology and Transcription factor. His ATF4 research is multidisciplinary, relying on both Signal transduction, Transcription Factor CHOP and Cell fate determination. Unfolded protein response is the subject of his research, which falls under Biochemistry.
Michael S. Kilberg has researched Activating Transcription Factor 4 in several fields, including Sp1 transcription factor, Sp3 transcription factor, TAF2 and ATF3. His Molecular biology research includes elements of Cell culture, Aspartate—ammonia ligase, Endoplasmic reticulum and Transcription, Gene. His Response element research includes themes of Luciferase, ATF/CREB and Asparagine synthetase, Asparagine.
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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
Jaeseok Han;Sung Hoon Back;Junguk Hur;Yu Hsuan Lin.
Nature Cell Biology (2013)
A Caveolar Complex between the Cationic Amino Acid Transporter 1 and Endothelial Nitric-oxide Synthase May Explain the “Arginine Paradox”
Kelly K. McDonald;Sergei Zharikov;Edward R. Block;Michael S. Kilberg.
Journal of Biological Chemistry (1997)
The regulation of neutral amino acid transport in mammalian cells.
Mark A. Shotwell;Michael S. Kilberg;Dale L. Oxender.
Biochimica et Biophysica Acta (1983)
Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.
M.S. Kilberg;M.E. Handlogten;H.N. Christensen.
Journal of Biological Chemistry (1980)
ATF4-dependent transcription mediates signaling of amino acid limitation
Michael S. Kilberg;Jixiu Shan;Nan Su.
Trends in Endocrinology and Metabolism (2009)
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress.
L Bouman;A Schlierf;A K Lutz;J Shan.
Cell Death & Differentiation (2011)
NUTRITIONAL CONTROL OF GENE EXPRESSION: How Mammalian Cells Respond to Amino Acid Limitation*
M.S. Kilberg;Y.-X. Pan;H. Chen;V. Leung-Pineda.
Annual Review of Nutrition (2005)
Amino acid transport in isolated rat hepatocytes
Michael S. Kilberg.
The Journal of Membrane Biology (1982)
ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene.
Fai Siu;Perry J. Bain;Rene LeBlanc-Chaffin;Hong Chen.
Journal of Biological Chemistry (2002)
Recent Advances in Mammalian Amino Acid Transport
Michael S. Kilberg;Bruce R. Stevens;Donald A. Novak.
Annual Review of Nutrition (1993)
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