D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 66 Citations 14,889 177 World Ranking 5577 National Ranking 2676

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

His primary scientific interests are in Biochemistry, Amino acid, Asparagine synthetase, ATF4 and Molecular biology. His study in Biochemistry focuses on Asparagine, Hepatocyte, Gene, Serine and Cysteine. The study incorporates disciplines such as Membrane transport, Gene expression and Messenger RNA in addition to Amino acid.

His biological study spans a wide range of topics, including Signal transduction and Transcription Factor CHOP. Transcriptional regulation and CREB is closely connected to Endoplasmic reticulum in his research, which is encompassed under the umbrella topic of Molecular biology. His study focuses on the intersection of Transcription factor and fields such as Transcription with connections in the field of ATF3.

His most cited work include:

  • ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death (889 citations)
  • A Caveolar Complex between the Cationic Amino Acid Transporter 1 and Endothelial Nitric-oxide Synthase May Explain the “Arginine Paradox” (422 citations)
  • The regulation of neutral amino acid transport in mammalian cells. (407 citations)

What are the main themes of his work throughout his whole career to date?

Michael S. Kilberg focuses on Biochemistry, Amino acid, Molecular biology, Asparagine synthetase and Cell biology. His Amino acid study incorporates themes from Endocrinology and Gene expression, Messenger RNA, Gene. Michael S. Kilberg interconnects Transcription factor, ATF4, Response element, RNA polymerase II and Transcription in the investigation of issues within Molecular biology.

His Transcription factor study combines topics from a wide range of disciplines, such as Unfolded protein response and Regulation of gene expression. His research in ATF4 intersects with topics in Signal transduction and Transcription Factor CHOP. His Asparagine synthetase research is multidisciplinary, incorporating elements of Cancer research, Endoplasmic reticulum, Transcriptional regulation and In vitro.

He most often published in these fields:

  • Biochemistry (60.34%)
  • Amino acid (58.05%)
  • Molecular biology (28.74%)

What were the highlights of his more recent work (between 2010-2020)?

  • ATF4 (12.07%)
  • Molecular biology (28.74%)
  • Cell biology (15.52%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are ATF4, Molecular biology, Cell biology, Activating Transcription Factor 4 and Asparagine. Michael S. Kilberg combines subjects such as Cancer research, Signal transduction and Activating transcription factor with his study of ATF4. His research integrates issues of Response element, RNA polymerase II, Transcription and Activating transcription factor 2 in his study of Molecular biology.

His studies in Cell biology integrate themes in fields like Inflammation, Downregulation and upregulation and Epigenetics. His study on Asparagine is covered under Biochemistry. His Asparagine synthetase study introduces a deeper knowledge of Amino acid.

Between 2010 and 2020, his most popular works were:

  • ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death (889 citations)
  • Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress. (221 citations)
  • Asparagine synthetase: regulation by cell stress and involvement in tumor biology. (128 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

Michael S. Kilberg spends much of his time researching ATF4, Unfolded protein response, Activating Transcription Factor 4, Molecular biology and Transcription factor. His ATF4 research is multidisciplinary, relying on both Signal transduction, Transcription Factor CHOP and Cell fate determination. Unfolded protein response is the subject of his research, which falls under Biochemistry.

Michael S. Kilberg has researched Activating Transcription Factor 4 in several fields, including Sp1 transcription factor, Sp3 transcription factor, TAF2 and ATF3. His Molecular biology research includes elements of Cell culture, Aspartate—ammonia ligase, Endoplasmic reticulum and Transcription, Gene. His Response element research includes themes of Luciferase, ATF/CREB and Asparagine synthetase, Asparagine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Jaeseok Han;Sung Hoon Back;Junguk Hur;Yu Hsuan Lin.
Nature Cell Biology (2013)

1324 Citations

A Caveolar Complex between the Cationic Amino Acid Transporter 1 and Endothelial Nitric-oxide Synthase May Explain the “Arginine Paradox”

Kelly K. McDonald;Sergei Zharikov;Edward R. Block;Michael S. Kilberg.
Journal of Biological Chemistry (1997)

647 Citations

The regulation of neutral amino acid transport in mammalian cells.

Mark A. Shotwell;Michael S. Kilberg;Dale L. Oxender.
Biochimica et Biophysica Acta (1983)

634 Citations

Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.

M.S. Kilberg;M.E. Handlogten;H.N. Christensen.
Journal of Biological Chemistry (1980)

562 Citations

ATF4-dependent transcription mediates signaling of amino acid limitation

Michael S. Kilberg;Jixiu Shan;Nan Su.
Trends in Endocrinology and Metabolism (2009)

531 Citations

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress.

L Bouman;A Schlierf;A K Lutz;J Shan.
Cell Death & Differentiation (2011)

319 Citations

NUTRITIONAL CONTROL OF GENE EXPRESSION: How Mammalian Cells Respond to Amino Acid Limitation*

M.S. Kilberg;Y.-X. Pan;H. Chen;V. Leung-Pineda.
Annual Review of Nutrition (2005)

306 Citations

Amino acid transport in isolated rat hepatocytes

Michael S. Kilberg.
The Journal of Membrane Biology (1982)

284 Citations

ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene.

Fai Siu;Perry J. Bain;Rene LeBlanc-Chaffin;Hong Chen.
Journal of Biological Chemistry (2002)

280 Citations

Recent Advances in Mammalian Amino Acid Transport

Michael S. Kilberg;Bruce R. Stevens;Donald A. Novak.
Annual Review of Nutrition (1993)

269 Citations

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