World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
17823
World Ranking
6656
National Ranking
3095

Overview

Michael S. Kilberg is affiliated with the University of Florida in the United States and is active in the field of biochemistry, genetics, and molecular biology. Their research spans multiple specialized subfields including molecular biology, biochemistry, clinical biochemistry, cell biology, and cancer research.

The scientist's work concentrates on topics related to amino acid enzymes and metabolism, biochemical and molecular research, epigenetics and DNA methylation, cancer, hypoxia, and metabolism, metabolism and genetic disorders, cancer-related molecular pathways, and acute lymphoblastic leukemia research.

Recent publications by Michael S. Kilberg include:

  • Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia, 2020, Frontiers in Oncology
  • Myeloma Cells Deplete Bone Marrow Glutamine and Inhibit Osteoblast Differentiation Limiting Asparagine Availability, 2020, Cancers
  • PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation, 2020, eLife
  • Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a, 2021, PLoS Genetics
  • Cellular and molecular characterization of two novel asparagine synthetase gene mutations linked to asparagine synthetase deficiency, 2022, Journal of Biological Chemistry

Their frequent coauthors include Stephen J. Staklinski, Mario C. Chang, Matthew E. Merritt, Massimiliano G. Bianchi, and Ovidio Bussolati.

Michael S. Kilberg has published in various scientific journals, with repeated contributions to these venues:

  • Frontiers in Oncology
  • Cancers
  • eLife
  • PLoS Genetics
  • Nutrients

Best Publications

  • ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

    Jaeseok Han;Sung Hoon Back;Junguk Hur;Yu Hsuan Lin

  • ATF4-dependent transcription mediates signaling of amino acid limitation.

    Michael S. Kilberg;Jixiu Shan;Nan Su

  • A Caveolar Complex between the Cationic Amino Acid Transporter 1 and Endothelial Nitric-oxide Synthase May Explain the “Arginine Paradox”

    Kelly K. McDonald;Sergei Zharikov;Edward R. Block;Michael S. Kilberg

  • The regulation of neutral amino acid transport in mammalian cells.

    Mark A. Shotwell;Michael S. Kilberg;Dale L. Oxender

  • Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.

    M.S. Kilberg;M.E. Handlogten;H.N. Christensen

  • Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells

    Inge M.N. Wortel;Laurens T. van der Meer;Michael S. Kilberg;Frank N. van Leeuwen

  • Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress.

    L Bouman;A Schlierf;A K Lutz;J Shan

  • NUTRITIONAL CONTROL OF GENE EXPRESSION: How Mammalian Cells Respond to Amino Acid Limitation*

    M.S. Kilberg;Y.-X. Pan;H. Chen;V. Leung-Pineda

  • ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene.

    Fai Siu;Perry J. Bain;Rene LeBlanc-Chaffin;Hong Chen

  • Amino acid transport in isolated rat hepatocytes

    Michael S. Kilberg

  • Asparagine synthetase: Function, structure, and role in disease

    Carrie L. Lomelino;Jacob T. Andring;Robert McKenna;Michael S. Kilberg

  • Asparagine synthetase chemotherapy.

    Nigel G. J. Richards;Michael S. Kilberg

  • Amino Acid Deprivation Induces the Transcription Rate of the Human Asparagine Synthetase Gene through a Timed Program of Expression and Promoter Binding of Nutrient-responsive Basic Region/Leucine Zipper Transcription Factors as Well as Localized Histone Acetylation

    Hong Chen;Yuan Xiang Pan;Elizabeth E. Dudenhausen;Michael S. Kilberg

  • MOLECULAR BIOLOGY OF MAMMALIAN AMINO ACID TRANSPORTERS

    Marc S. Malandro;Michael S. Kilberg

  • Recent Advances in Mammalian Amino Acid Transport

    Michael S. Kilberg;Bruce R. Stevens;Donald A. Novak

  • Neutral amino acid transport systems in Chinese hamster ovary cells.

    M A Shotwell;D W Jayme;M S Kilberg;D L Oxender

  • Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.

    Saad Shafqat;Balaji K. Tamarappoo;Michael S. Kilberg;Ram S. Puranam

  • CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis

    Brian F. Teske;Michael E. Fusakio;Donghui Zhou;Jixiu Shan

  • C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene.

    Nan Su;Michael S. Kilberg

  • Characteristics of system ASC for transport of neutral amino acids in the isolated rat hepatocyte.

    M S Kilberg;M E Handlogten;H N Christensen

Frequent Co-Authors

Halvor N. Christensen
Halvor N. Christensen University of Michigan–Ann Arbor
Harry S. Nick
Harry S. Nick University of Florida
Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Maria Hatzoglou
Maria Hatzoglou Case Western Reserve University
Anupam Agarwal
Anupam Agarwal University of Alabama at Birmingham
Naohiro Terada
Naohiro Terada University of Florida
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Tony Roscioli
Tony Roscioli University of New South Wales
Marcel E. Dinger
Marcel E. Dinger University of Sydney
Mark J. Cowley
Mark J. Cowley Garvan Institute of Medical Research

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry opens doors to a wide range of specialized and impactful career options. Many students now choose to pursue flexible, accredited programs online across related disciplines. For example, if you are interested in medicines and patient care, an online pharmacy school can lead to rewarding roles in healthcare and pharmaceutical sciences.

For those passionate about health, movement, and wellness, there are robust fitness degrees online as well as online kinesiology programs. These programs teach vital skills for coaching, physical therapy, or research roles within sports and wellness industries.

If you are looking to fast-track your pathway to specialized nursing roles, a 1 year pmhnp program online offers a streamlined approach to entering mental health nurse practitioner positions.

Online degrees in these science-focused areas provide practical, in-demand knowledge while accommodating busy schedules. Students can align their education with career ambitions, gaining expertise to thrive in a variety of fields related to biology and biochemistry.

Best Scientists Citing Michael S. Kilberg

Trending Scientists