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Yoshikatsu Kanai

Yoshikatsu Kanai

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
115
Citations
49980
World Ranking
786
National Ranking
36

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Yoshikatsu Kanai is affiliated with Osaka University in Japan and has contributed extensively to the field of biochemistry and molecular biology with a focus on transporter proteins and cancer-related pathways. Their research spans multiple disciplines within medicine and molecular biology, reflecting a broad interest in cellular metabolism and therapeutic targets.

The scientist's notable recent publications include:

  • "Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics" (2021, Pharmacology & Therapeutics)
  • "THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters" (2021, British Journal of Pharmacology)
  • "The Concise Guide to PHARMACOLOGY 2023/24: Transporters" (2023, British Journal of Pharmacology)
  • "Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma" (2020, Scientific Reports)
  • "Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application" (2020, Pflügers Archiv - European Journal of Physiology)

Their collaborative network includes frequent co-authors such as Ryuichi Ohgaki, Hiroki Okanishi, Shushi Nagamori, Suguru Okuda, and Chunhuan Jin, with whom they have published numerous papers. This network illustrates an active engagement with peers in related research areas.

Yoshikatsu Kanai's research has been published predominantly in the following venues:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Scientific Reports
  • Cancer Science
  • Journal of Pharmacological Sciences
  • Nature Communications

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their work focuses on the following subfields:

  • Molecular Biology
  • Biochemistry
  • Oncology
  • Genetics
  • Materials Chemistry

The core topics of Yoshikatsu Kanai's research include:

  • Amino Acid Enzymes and Metabolism
  • Epigenetics and DNA Methylation
  • Polyamine Metabolism and Applications
  • Drug Transport and Resistance Mechanisms
  • Metabolism and Genetic Disorders
  • Chemical Synthesis and Analysis
  • Cancer-related Molecular Pathways

Best Publications

  • Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

    Jeffrey D Rothstein;Margaret Dykes-Hoberg;Carlos A Pardo;Lynn A Bristol

  • Molecular identification of a renal urate anion exchanger that regulates blood urate levels.

    Atsushi Enomoto;Hiroaki Kimura;Hiroaki Kimura;Arthit Chairoungdua;Yasuhiro Shigeta;Yasuhiro Shigeta

  • Primary structure and functional characterization of a high-affinity glutamate transporter

    Yoshikatsu Kanai;Matthias A. Hediger;Matthias A. Hediger

  • Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

    Yoshikatsu Kanai;Hiroko Segawa;Hiroko Segawa;Ken-ichi Miyamoto;Hiroshi Uchino;Hiroshi Uchino

  • Expression cloning of a mammalian proton-coupled oligopeptide transporter

    You Jun Fei;You Jun Fei;Yoshikatsu Kanai;Yoshikatsu Kanai;Stephan Nussberger;Vadivel Ganapathy

  • Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter

    Takashi Sekine;Nobuaki Watanabe;Makoto Hosoyamada;Yoshikatsu Kanai

  • Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.

    Osamu Yanagida;Yoshikatsu Kanai;Yoshikatsu Kanai;Arthit Chairoungdua;Do Kyung Kim

  • CATs and HATs: the SLC7 family of amino acid transporters

    François Verrey;Ellen I. Closs;Carsten A. Wagner;Manuel Palacin

  • The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

    Yoshikatsu Kanai;Wen Sen Lee;Guofeng You;Dennis Brown

  • The SLC3 and SLC7 families of amino acid transporters

    Dimitrios Fotiadis;Yoshikatsu Kanai;Manuel Palacín

  • Cloning and Functional Characterization of a System ASC-like Na+-dependent Neutral Amino Acid Transporter

    Naoko Utsunomiya-Tate;Hitoshi Endou;Yoshikatsu Kanai

  • Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney

    Seok Ho Cha;Takashi Sekine;Jun-ichi Fukushima;Yoshikatsu Kanai

  • Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain

    Hiroyuki Kusuhara;Takashi Sekine;Naoko Utsunomiya-Tate;Minoru Tsuda

  • Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity.

    Hiroko Segawa;Hiroko Segawa;Yoshiki Fukasawa;Ken-ichi Miyamoto;Eiji Takeda

  • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

    Seok Ho Cha;Takashi Sekine;Hiroyuki Kusuhara;Hiroyuki Kusuhara;Erkang Yu

  • Transport of Amino Acid-Related Compounds Mediated by L-Type Amino Acid Transporter 1 (LAT1): Insights Into the Mechanisms of Substrate Recognition

    Hiroshi Uchino;Yoshikatsu Kanai;Do Kyung Kim;Michael F. Wempe

  • Common defects of ABCG2, a high-capacity urate exporter, cause gout: A function-based genetic analysis in a Japanese population

    Hirotaka Matsuo;Tappei Takada;Kimiyoshi Ichida;Kimiyoshi Ichida;Takahiro Nakamura

  • The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects

    Yoshikatsu Kanai;Matthias A. Hediger

  • Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney.

    Makoto Hosoyamada;Takashi Sekine;Yoshikatsu Kanai;Hitoshi Endou

  • Identification of multispecific organic anion transporter 2 expressed predominantly in the liver

    Takashi Sekine;Seok Ho Cha;Minoru Tsuda;Nopporn Apiwattanakul

Frequent Co-Authors

Hitoshi Endou
Hitoshi Endou Kyorin University
Naohiko Anzai
Naohiko Anzai Chiba University
Matthias A. Hediger
Matthias A. Hediger University of Bern
Atsushi Enomoto
Atsushi Enomoto Nagoya University
Masatomo Mori
Masatomo Mori Gunma University
Wen Sen Lee
Wen Sen Lee Taipei Medical University
Thomas Jansson
Thomas Jansson The University of Texas Health Science Center at San Antonio
Theresa L. Powell
Theresa L. Powell University of Colorado Anschutz Medical Campus
Hiroyuki Kuwano
Hiroyuki Kuwano Gunma University
Keigo Endo
Keigo Endo Gunma University

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