World's Best Scientists 2026 revealed!
Yuichi Sugiyama

Yuichi Sugiyama

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Medicine
Japan
2023

D-Index & Metrics

Medicine

D-Index
140
Citations
71794
World Ranking
1698
National Ranking
33

Yuichi Sugiyama publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Yuichi Sugiyama sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 961 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Yuichi Sugiyama D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Yuichi Sugiyama sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 140 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Yuichi Sugiyama is affiliated with the University of Tokyo in Japan and has produced a significant body of research primarily in the field of Medicine, with a focus on Oncology, Pharmacology, Pediatrics, Perinatology and Child Health, Molecular Biology, and Infectious Diseases.

Their research spans several interconnected topics, including:

  • Drug Transport and Resistance Mechanisms
  • Pharmacogenetics and Drug Metabolism
  • Pharmacological Effects and Toxicity Studies
  • HIV/AIDS drug development and treatment
  • Liver Disease Diagnosis and Treatment
  • Amino Acid Enzymes and Metabolism
  • Diabetes Treatment and Management

Yuichi Sugiyama has contributed multiple papers to a variety of scientific journals. Some recent publications include:

  • "Phase 0/microdosing approaches: time for mainstream application in drug development?" (2020) in Nature Reviews Drug Discovery
  • "Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance" (2022) in Clinical Pharmacology & Therapeutics
  • "Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications" (2020) in Clinical Pharmacology & Therapeutics
  • "Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein-Mediated Drug-Drug Interactions in Healthy Volunteers" (2020) in Clinical Pharmacology & Therapeutics
  • "Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion-transporting polypeptides" (2020) in Journal of Biological Chemistry

Their work frequently appears in several publication venues, mainly:

  • Clinical Pharmacology & Therapeutics
  • CPT Pharmacometrics & Systems Pharmacology
  • Drug Metabolism and Pharmacokinetics
  • Drug Metabolism and Disposition
  • Journal of Pharmaceutical Sciences

Collaborations with other researchers have been a notable aspect of Sugiyama's career. Frequent co-authors include:

  • Hiroyuki Kusuhara
  • Wooin Lee
  • Yasunori Aoki
  • Xiaoyan Chu
  • Kazuya Maeda

Best Publications

  • Membrane transporters in drug development.

    Kathleen M. Giacomini;Shiew Mei Huang;Donald J. Tweedie;Leslie Z. Benet

  • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

    Patricio Godoy;Nicola J. Hewitt;Ute Albrecht;Melvin E. Andersen

  • Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: Drug–drug interactions and interindividual differences in transporter and metabolic enzyme functions

    Yoshihisa Shitara;Yuichi Sugiyama

  • Novel Cisplatin-Incorporated Polymeric Micelles Can Eradicate Solid Tumors in Mice

    Nobuhiro Nishiyama;Souichiro Okazaki;Horacio Cabral;Masaki Miyamoto

  • Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

    Yohei Nishizato;Ichiro Ieiri;Hiroshi Suzuki;Miyuki Kimura

  • Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain

    Hiroyuki Kusuhara;Takashi Sekine;Naoko Utsunomiya-Tate;Minoru Tsuda

  • Impact of Drug Transporter Studies on Drug Discovery and Development

    Naomi Mizuno;Takuro Niwa;Yoshihisa Yotsumoto;Yuichi Sugiyama

  • Transporters as a determinant of drug clearance and tissue distribution.

    Yoshihisa Shitara;Toshiharu Horie;Yuichi Sugiyama

  • Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver.

    K. Ito;T. Iwatsubo;S. Kanamitsu;K. Ueda

  • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

    Seok Ho Cha;Takashi Sekine;Hiroyuki Kusuhara;Hiroyuki Kusuhara;Erkang Yu

  • Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

    Takafumi Iwatsubo;Noriko Hirota;Tsuyoshi Ooie;Hiroshi Suzuki

  • Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil

    Yoshihisa Shitara;Masaru Hirano;Hitoshi Sato;Yuichi Sugiyama

  • Involvement of Organic Cation Transporter 1 in Hepatic and Intestinal Distribution of Metformin

    De-Sheng Wang;Johan W. Jonker;Yukio Kato;Hiroyuki Kusuhara

  • Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge.

    Yuji Yamamoto;Yukio Nagasaki;Yukio Kato;Yuichi Sugiyama

  • Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans

    Masaru Hirano;Kazuya Maeda;Yoshihisa Shitara;Yuichi Sugiyama

  • Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

    Tomoko Hirohashi;Hiroshi Suzuki;Yuichi Sugiyama

  • EVALUATION OF DRUG-DRUG INTERACTION IN THE HEPATOBILIARY AND RENAL TRANSPORT OF DRUGS

    Yoshihisa Shitara;Hitoshi Sato;Yuichi Sugiyama

  • ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3).

    Tomoko Hirohashi;Hiroshi Suzuki;Hajime Takikawa;Yuichi Sugiyama

  • Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption.

    Yoshihisa Shitara;Kazuya Maeda;Kazuaki Ikejiri;Kenta Yoshida

  • Inhibition of Transporter-Mediated Hepatic Uptake as a Mechanism for Drug-Drug Interaction between Cerivastatin and Cyclosporin A

    Yoshihisa Shitara;Tomoo Itoh;Hitoshi Sato;Albert P. Li

Frequent Co-Authors

Hiroyuki Kusuhara
Hiroyuki Kusuhara University of Tokyo
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
Tetsuya Terasaki
Tetsuya Terasaki Tohoku University
Hitoshi Endou
Hitoshi Endou Kyorin University
Yasuyoshi Watanabe
Yasuyoshi Watanabe Osaka Metropolitan University
Naoki Ishiguro
Naoki Ishiguro Nagoya University
John D. Schuetz
John D. Schuetz St. Jude Children's Research Hospital
Alfred H. Schinkel
Alfred H. Schinkel Antoni van Leeuwenhoek Hospital
Bruno Stieger
Bruno Stieger University of Zurich
Tetsuya Suhara
Tetsuya Suhara National Institutes for Quantum and Radiological Science and Technology

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