World's Best Scientists 2026 revealed!
Hitoshi Endou

Hitoshi Endou

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
111
Citations
42809
World Ranking
941
National Ranking
45

Medicine

D-Index
111
Citations
42745
World Ranking
5355
National Ranking
114

Hitoshi Endou publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hitoshi Endou sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 566 publications — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hitoshi Endou D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hitoshi Endou sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 111 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Hitoshi Endou is affiliated with Kyorin University in Japan and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research output includes 63 publications primarily focused on molecular biology, biochemistry, immunology, and oncology, with specific subfields such as cancer research. The main themes of their work involve amino acid enzymes and metabolism, epigenetics and DNA methylation, polyamine metabolism and applications, immune cell function and interaction, mast cells and histamine, cancer, hypoxia, and metabolism, and drug transport and resistance mechanisms.

Endou's recent scientific papers cover a range of molecular and cellular topics related to cancer and amino acid transport. Key papers include:

  • First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors (2020, Investigational New Drugs)
  • Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor (2020, Cancer Science)
  • Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation (2020, Journal of Experimental & Clinical Cancer Research)
  • Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment (2022, Blood Advances)
  • Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells (2022, Journal of Cellular and Molecular Medicine)

Frequent coauthors collaborating with Endou on multiple studies include Hiroki Okanishi, Ryuichi Ohgaki, Yoshikatsu Kanai, Suguru Okuda, and Keitaro Hayashi, reflecting an active network in molecular and cancer biology research.

Their work has been published repeatedly in venues such as the Proceedings for Annual Meeting of The Japanese Pharmacological Society, Scientific Reports, Journal of Pharmacological Sciences, Investigational New Drugs, and Cancer Science, indicating a focus on pharmacology, cancer biology, and molecular medicine.

The research topics associated with Endou emphasize amino acid transporters like LAT1 and their role in cancer cell metabolism, tumor environment adaptation, and vascular endothelium function. Studies also explore the interaction between molecular transport mechanisms and cellular signaling pathways, including mTORC1 activation and global translation regulation.

Best Publications

  • Molecular identification of a renal urate anion exchanger that regulates blood urate levels.

    Atsushi Enomoto;Hiroaki Kimura;Hiroaki Kimura;Arthit Chairoungdua;Yasuhiro Shigeta;Yasuhiro Shigeta

  • Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

    Yoshikatsu Kanai;Hiroko Segawa;Hiroko Segawa;Ken-ichi Miyamoto;Hiroshi Uchino;Hiroshi Uchino

  • Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter

    Takashi Sekine;Nobuaki Watanabe;Makoto Hosoyamada;Yoshikatsu Kanai

  • Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.

    Osamu Yanagida;Yoshikatsu Kanai;Yoshikatsu Kanai;Arthit Chairoungdua;Do Kyung Kim

  • CATs and HATs: the SLC7 family of amino acid transporters

    François Verrey;Ellen I. Closs;Carsten A. Wagner;Manuel Palacin

  • The SLC22 drug transporter family.

    Hermann Koepsell;Hitoshi Endou

  • Cloning and Functional Characterization of a System ASC-like Na+-dependent Neutral Amino Acid Transporter

    Naoko Utsunomiya-Tate;Hitoshi Endou;Yoshikatsu Kanai

  • Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney

    Seok Ho Cha;Takashi Sekine;Jun-ichi Fukushima;Yoshikatsu Kanai

  • Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain

    Hiroyuki Kusuhara;Takashi Sekine;Naoko Utsunomiya-Tate;Minoru Tsuda

  • Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity.

    Hiroko Segawa;Hiroko Segawa;Yoshiki Fukasawa;Ken-ichi Miyamoto;Eiji Takeda

  • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

    Seok Ho Cha;Takashi Sekine;Hiroyuki Kusuhara;Hiroyuki Kusuhara;Erkang Yu

  • Transport of Amino Acid-Related Compounds Mediated by L-Type Amino Acid Transporter 1 (LAT1): Insights Into the Mechanisms of Substrate Recognition

    Hiroshi Uchino;Yoshikatsu Kanai;Do Kyung Kim;Michael F. Wempe

  • Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney.

    Makoto Hosoyamada;Takashi Sekine;Yoshikatsu Kanai;Hitoshi Endou

  • Identification of multispecific organic anion transporter 2 expressed predominantly in the liver

    Takashi Sekine;Seok Ho Cha;Minoru Tsuda;Nopporn Apiwattanakul

  • Clinical and Molecular Analysis of Patients with Renal Hypouricemia in Japan-Influence of URAT1 Gene on Urinary Urate Excretion

    Kimiyoshi Ichida;Makoto Hosoyamada;Ichiro Hisatome;Atsushi Enomoto

  • Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans.

    Naohiko Anzai;Kimiyoshi Ichida;Promsuk Jutabha;Toru Kimura

  • Identification and characterization of the high-affinity choline transporter

    Takashi Okuda;Tatsuya Haga;Yoshikatsu Kanai;Hitoshi Endou

  • The multispecific organic anion transporter (OAT) family.

    Takashi Sekine;Seok Ho Cha;Hitoshi Endou

  • Molecular Physiology of Urate Transport

    Matthias A. Hediger;Richard J Johnson;Hiroki Miyazaki;Hitoshi Endou

  • Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids.

    Yoshiki Fukasawa;Hiroko Segawa;Hiroko Segawa;Ju Young Kim;Arthit Chairoungdua

Frequent Co-Authors

Yoshikatsu Kanai
Yoshikatsu Kanai Osaka University
Naohiko Anzai
Naohiko Anzai Chiba University
Atsushi Enomoto
Atsushi Enomoto Nagoya University
Hiroyuki Kusuhara
Hiroyuki Kusuhara University of Tokyo
Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Toshiro Fujita
Toshiro Fujita University of Tokyo
Eiji Takeda
Eiji Takeda University of Tokushima
Masatomo Mori
Masatomo Mori Gunma University
Hisashi Yamanaka
Hisashi Yamanaka International University of Health and Welfare
Tsutomu Suzuki
Tsutomu Suzuki University of Tokyo

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