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D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
24409
World Ranking
2367
National Ranking
1261

Overview

Sanjay K. Nigam is affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to several subfields including Pharmacology, Oncology, Molecular Biology, Biochemistry, and Pediatrics, Perinatology and Child Health.

They have focused extensively on topics such as Drug Transport and Resistance Mechanisms, Pharmacogenetics and Drug Metabolism, Amino Acid Enzymes and Metabolism, Pharmacological Effects and Toxicity Studies, Cannabis and Cannabinoid Research, Metabolomics and Mass Spectrometry Studies, and Hemoglobinopathies and Related Disorders.

Frequent coauthors in their work include Jeffry C. Granados, Anisha K. Nigam, Vibha Bhatnagar, Kevin T. Bush, and Neema Jamshidi.

They have published multiple papers in notable venues including the International Journal of Molecular Sciences, JCI Insight, Journal of Biological Chemistry, Clinical Pharmacology & Therapeutics, and Scientific Reports.

Among their recent publications are:

  • Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs, 2020, International Journal of Molecular Sciences
  • Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease, 2020, JCI Insight
  • Role of the Microbiome in Gut-Heart-Kidney Cross Talk, 2023, Circulation Research
  • AHR is a master regulator of diverse pathways in endogenous metabolism, 2022, Scientific Reports
  • Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning, 2020, Journal of Biological Chemistry

Best Publications

  • Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis

    Xue Li;Kenneth A. Oghi;Jie Zhang;Anna Krones

  • What do drug transporters really do

    Sanjay K. Nigam

  • Molecular structure and assembly of the tight junction

    Bradley M. Denker;Sanjay K. Nigam

  • Proteasome Inhibition Leads to a Heat-shock Response, Induction of Endoplasmic Reticulum Chaperones, and Thermotolerance

    Kevin T. Bush;Alfred L. Goldberg;Sanjay K. Nigam

  • Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease

    Kumar Sharma;Bethany Karl;Anna V. Mathew;Jon A. Gangoiti

  • The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective

    Sanjay K. Nigam;Kevin T. Bush;Gleb Martovetsky;Sun-Young Ahn

  • Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction.

    Eliot M. Rosen;Sanjay K. Nigam;Itzhak D. Goldberg

  • Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable.

    Wilfred Lieberthal;Sanjay K. Nigam

  • A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2+)-binding proteins and members of the thioredoxin superfamily.

    S K Nigam;A L Goldberg;S Ho;M F Rohde

  • Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

    Douglas H. Sweet;David S. Miller;John B. Pritchard;Yuko Fujiwara

  • Regulated assembly of tight junctions by protein kinase C.

    Robert O. Stuart;Sanjay K. Nigam

  • An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse.

    Michael Rauchman;Sanjay K. Nigam;Eric Delpire;Steven R. Gullans

  • Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters

    Sanjay K. Nigam;Wei Wu;Kevin T. Bush;Melanie P. Hoenig

  • Molecular Cloning and Characterization of NKT, a Gene Product Related to the Organic Cation Transporter Family That Is Almost Exclusively Expressed in the Kidney

    Carlos E. Lopez-Nieto;Guofeng You;Kevin T. Bush;Elvino J.G. Barros

  • Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins.

    Tatsuo Tsukamoto;Sanjay K. Nigam

  • Tight Junction Proteins Form Large Complexes and Associate with the Cytoskeleton in an ATP Depletion Model for Reversible Junction Assembly

    Tatsuo Tsukamoto;Sanjay K. Nigam

  • Branching morphogenesis independent of mesenchymal-epithelial contact in the developing kidney.

    Jizeng Qiao;Hiroyuki Sakurai;Sanjay K. Nigam

  • Multiple organic anion transporters contribute to net renal excretion of uric acid

    Satish A. Eraly;Volker Vallon;Volker Vallon;Timo Rieg;Timo Rieg;Jon A. Gangoiti

  • Acute renal failure. I. Relative importance of proximal vs. distal tubular injury

    Wilfred Lieberthal;Sanjay K. Nigam

  • HGF-Induced Tubulogenesis and Branching of Epithelial Cells Is Modulated by Extracellular Matrix and TGF-β

    Oscar F.P. Santos;Sanjay K. Nigam

Frequent Co-Authors

Kevin T. Bush
Kevin T. Bush University of California, San Diego
Volker Vallon
Volker Vallon University of California, San Diego
Jeffrey D. Esko
Jeffrey D. Esko University of California, San Diego
Ruben Abagyan
Ruben Abagyan University of California, San Diego
David W. Rose
David W. Rose University of California, San Diego
Karl Willert
Karl Willert University of California, San Diego
Jordan A. Kreidberg
Jordan A. Kreidberg Boston Children's Hospital
Roy Zent
Roy Zent Vanderbilt University Medical Center
David R. Beier
David R. Beier Seattle Children's Hospital
Bernhard O. Palsson
Bernhard O. Palsson University of California, San Diego

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