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D-Index & Metrics

Genetics

D-Index
69
Citations
20764
World Ranking
2331
National Ranking
1052

Overview

David R. Beier is affiliated with Seattle Children's Hospital in the United States. Their research spans multiple fields, with a focus on biochemistry, genetics, molecular biology, and medicine. Within these broader categories, their work delves into molecular biology, genetics, cardiology and cardiovascular medicine, surgery, and cell biology.

They have published extensively on subjects including renal and related cancers, cardiac fibrosis and remodeling, genetic and kidney cyst diseases, Hedgehog signaling pathway studies, epigenetics and DNA methylation, single-cell and spatial transcriptomics, and RNA research and splicing.

Their recent publications encompass a range of topics and venues:

  • Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis (2021, iScience)
  • Single-cell, whole-embryo phenotyping of mammalian developmental disorders (2023, Nature)
  • Isolation and Characterization of Adult Cardiac Fibroblasts and Myofibroblasts (2020, Journal of Visualized Experiments)
  • Reelin Mediates Hippocampal Cajal-Retzius Cell Positioning and Infrapyramidal Blade Morphogenesis (2020, Journal of Developmental Biology)
  • Mammalian organ regeneration in spiny mice (2022, Journal of Muscle Research and Cell Motility)

David R. Beier frequently collaborates with other researchers. Notable coauthors include:

  • Elizabeth D. Nguyen
  • Daryl M. Okamura
  • Mark W. Majesky
  • Sarah Collins
  • Scott Houghtaling

Their research is also regularly published in several scientific venues, with multiple contributions to:

  • Journal of the American Society of Nephrology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Visualized Experiments
  • G3 Genes Genomes Genetics
  • Developmental Biology

Best Publications

  • PRDM16 controls a brown fat/skeletal muscle switch

    Patrick Seale;Bryan Bjork;Wenli Yang;Shingo Kajimura

  • The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus.

    Eric Huang;Karl Nocka;David R. Beier;Tang-Yan Chu

  • Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene.

    Leonard D. Shultz;Peter A. Schweitzer;T.V. Rajan;Taolin Yi

  • The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.

    M. A. Thompson;D. G. Ransom;S. J. Pratt;H. Maclennan

  • Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice

    Michael P. Schön;Anu Arya;Elizabeth A. Murphy;Cassandra M. Adams

  • The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1.

    Debra D. Donaldson;Matthew J. Whitters;Lori J. Fitz;Tamlyn Yee Neben

  • Agouti C57BL/6N embryonic stem cells for mouse genetic resources.

    Stephen J. Pettitt;Qi Liang;Xin Y. Rairdan;Jennifer L. Moran;Jennifer L. Moran

  • Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription.

    K H In;K Asano;D Beier;J Grobholz

  • A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis

    Y Li;D.A Lacerda;M.L Warman;D.R Beier

  • Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode

    Pin-Xian Xu;Ian Woo;Helen Her;David R. Beier

  • THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

    Pamela V Tran;Courtney J Haycraft;Tatiana Y Besschetnova;Annick Turbe-Doan

  • Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice.

    G T De Sanctis;M Merchant;D R Beier;R D Dredge

  • Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

    Douglas H. Sweet;David S. Miller;John B. Pritchard;Yuko Fujiwara

  • Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis.

    J.Richard Chaillet;Thomas F. Vogt;David R. Beier;Philip Leder

  • Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells.

    E Delpire;M I Rauchman;D R Beier;S C Hebert

  • Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

    Xiaoying Hou;Michal Mrug;Bradley K. Yoder;Elliot J. Lefkowitz

  • The IFT-A Complex Regulates Shh Signaling through Cilia Structure and Membrane Protein Trafficking

    Karel F. Liem;Alyson Ashe;Mu He;Mu He;Peter Satir

  • A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish.

    Shanming Liu;Weining Lu;Tomoko Obara;Shiei Kuida

  • Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

    Amy M Pooler;Amy M Pooler;Manuela Polydoro;Eduardo A Maury;Samantha B Nicholls

  • Fog2 Is Required for Normal Diaphragm and Lung Development in Mice and Humans

    Kate G Ackerman;Bruce J Herron;Sara O Vargas;Hailu Huang

Frequent Co-Authors

Jennifer L. Moran
Jennifer L. Moran Broad Institute
Shamil R. Sunyaev
Shamil R. Sunyaev Harvard University
Jeffrey M. Drazen
Jeffrey M. Drazen Harvard University
Jagesh V. Shah
Jagesh V. Shah Harvard University
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
Robert F. Hevner
Robert F. Hevner University of California, San Diego
Sanjay K. Nigam
Sanjay K. Nigam University of California, San Diego
Roderick T. Bronson
Roderick T. Bronson Harvard University

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