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Philippe Gros

Philippe Gros

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Genetics
Canada
2024

D-Index & Metrics

Genetics

D-Index
118
Citations
46822
World Ranking
415
National Ranking
13

Research.com Recognitions

  • 2024 - Research.com Genetics in Canada Leader Award
  • 2023 - Research.com Genetics in Canada Leader Award
  • 2003 - Fellow of the Royal Society of Canada Academy of Science

Overview

Philippe Gros is a researcher affiliated with McGill University in Canada, specializing in Medicine and Immunology and Microbiology. Their work spans multiple subfields, including Immunology, Molecular Biology, Infectious Diseases, Genetics, and Oncology.

The main topics addressed in their research include:

  • Immune Cell Function and Interaction
  • Immunodeficiency and Autoimmune Disorders
  • T-cell and B-cell Immunology
  • Interferon and Immune Responses
  • Immunotherapy and Immune Responses
  • Tuberculosis Research and Epidemiology
  • Neonatal Respiratory Health Research

The scientist has published frequently in several venues, primarily:

  • Cell
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Genetics
  • Nature Medicine

Recent notable papers include:

  • "The hygiene hypothesis, the COVID pandemic, and consequences for the human microbiome" (2021), Proceedings of the National Academy of Sciences
  • "Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria" (2020), Cell
  • "Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases" (2020), Human Genetics
  • "Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child" (2021), Nature Medicine
  • "Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria" (2023), Cell

Philippe Gros collaborates regularly with several frequent co-authors, including:

  • Jean-Laurent Casanova
  • Nico Marr
  • Jacinta Bustamante
  • David Langlais
  • Taushif Khan

In recognition of their work, they were named a Fellow of the Royal Society of Canada in 2003, cited by the Academy of Science.

Best Publications

  • Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)

    Salman T. Qureshi;Line Larivière;Gary Leveque;Sophie Clermont

  • Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg.

    Silvia M. Vidal;Danielle Malo;Kyle Vogan;Emil Skamene

  • Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

    Philippe Gros;James Croop;James Croop;David Housman

  • Isolation and expression of a complementary DNA that confers multidrug resistance.

    Philippe Gros;Yinon Ben Neriah;Yinon Ben Neriah;James M. Croop;David E. Housman

  • Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells.

    Igor B. Roninson;Janice E. Chin;Kyunghee Choi;Philippe Gros

  • Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3.

    Douglas J. Epstein;Michel Vekemans;Philippe Gros

  • Phosphatidylcholine translocase: A physiological role for the mdr2 gene

    Stephan Ruetz;Philippe Gros

  • The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.

    S Vidal;M L Tremblay;G Govoni;S Gauthier

  • IRF8 mutations and human dendritic-cell immunodeficiency.

    Sophie Hambleton;Sandra Salem;Jacinta Bustamante;Venetia Bigley

  • Natural Resistance to Infection with Intracellular Pathogens: The Nramp1 Protein Is Recruited to the Membrane of the Phagosome

    Samantha Gruenheid;Elhanan Pinner;Michel Desjardins;Philippe Gros

  • The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.

    J M Croop;M Raymond;D Haber;A Devault

  • Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency

    Dusan Bogunovic;Minji Byun;Larissa A. Durfee;Avinash Abhyankar

  • Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

    Xianqin Zhang;Dusan Bogunovic;Béatrice Payelle-Brogard;Véronique Francois-Newton

  • Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.

    Z Kibar;K J Vogan;N Groulx;M J Justice

  • Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

    Jeremy Dupaul-Chicoine;Garabet Yeretssian;Karine Doiron;Kirk S.B. Bergstrom

  • Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron.

    F. Canonne-Hergaux;S. Gruenheid;S. Gruenheid;P. Ponka;P. Ponka;P. Gros;P. Gros

  • Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities.

    A Devault;P Gros

  • Natural Resistance to Intracellular Infections: Natural Resistance–Associated Macrophage Protein 1 (Nramp1) Functions as a Ph-Dependent Manganese Transporter at the Phagosomal Membrane

    Nada Jabado;Andrzej Jankowski;Samuel Dougaparsad;Virginie Picard

  • Susceptibility to mouse cytomegalovirus is associated with deletion of an activating natural killer cell receptor of the C-type lectin superfamily

    Seung-Hwan Lee;Sonia Girard;Denis Macina;Maria Busà

  • Genetic regulation of resistance to intracellular pathogens

    Emil Skamene;Philippe Gros;Adrien Forget;Patricia A. L. Kongshavn

Frequent Co-Authors

Emil Skamene
Emil Skamene McGill University
Danielle Malo
Danielle Malo McGill University
Silvia M. Vidal
Silvia M. Vidal McGill University
Erwin Schurr
Erwin Schurr McGill University Health Centre
Mary M. Stevenson
Mary M. Stevenson McGill University
Jerry Pelletier
Jerry Pelletier McGill University
Laurent Abel
Laurent Abel Université Paris Cité
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Kenneth Morgan
Kenneth Morgan McGill University

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