Susan P.C. Cole mostly deals with Biochemistry, Multidrug Resistance Protein 1, Multiple drug resistance, Glutathione and ATP-binding cassette transporter. Susan P.C. Cole applies her multidisciplinary studies on Biochemistry and Leukotriene C4 in her research. Her Multidrug Resistance Protein 1 study incorporates themes from ATPase, Organic anion, Glutathione transport, ABCC1 and Stereochemistry.
The various areas that Susan P.C. Cole examines in her ABCC1 study include Molecular biology, Multidrug Resistance-Associated Proteins and Organic anion transport. Her Multiple drug resistance research includes elements of Immunology, Cell culture, Transfection and Cancer research. Her ATP-binding cassette transporter study integrates concerns from other disciplines, such as Transport protein, P-glycoprotein and Membrane protein.
Her main research concerns Biochemistry, Molecular biology, Multidrug Resistance Protein 1, Cell culture and Multiple drug resistance. Her Biochemistry and ATP-binding cassette transporter, Glutathione, Transmembrane domain, Transporter and Amino acid investigations all form part of her Biochemistry research activities. Susan P.C. Cole has included themes like Messenger RNA, Gene, Transfection and Epitope, Antibody in her Molecular biology study.
As a part of the same scientific study, Susan P.C. Cole usually deals with the Multidrug Resistance Protein 1, concentrating on ABCC1 and frequently concerns with Efflux. Her study in Cell culture is interdisciplinary in nature, drawing from both Cell, Cancer research, Immunology, Antigen and Monoclonal antibody. Within one scientific family, Susan P.C. Cole focuses on topics pertaining to Etoposide under Multiple drug resistance, and may sometimes address concerns connected to Topoisomerase.
Her primary areas of study are Biochemistry, Multidrug Resistance Protein 1, ATP-binding cassette transporter, Transporter and ABCC1. Her study in Organic anion transport, Transmembrane domain, Multidrug Resistance-Associated Proteins, Multidrug resistance-associated protein 2 and Mutant are all subfields of Biochemistry. Her research integrates issues of Transport protein, Glutathione and Single-nucleotide polymorphism in her study of Multidrug Resistance Protein 1.
Her work on ABCC4 as part of her general ATP-binding cassette transporter study is frequently connected to Leukotriene C4, thereby bridging the divide between different branches of science. Her Transporter research integrates issues from Cytoplasm, In vitro and In vivo. Her work carried out in the field of ABCC1 brings together such families of science as SNP, Cancer research, Abcg2, Immunology and Pharmacogenetics.
Susan P.C. Cole mainly focuses on Biochemistry, Transporter, ABCC1, Multidrug Resistance Protein 1 and ATP-binding cassette transporter. Her study in Efflux and Drug metabolism is done as part of Biochemistry. In her study, Multiple drug resistance and Xenobiotic is inextricably linked to Multidrug Resistance-Associated Proteins, which falls within the broad field of Efflux.
Her studies deal with areas such as P-glycoprotein and Transmembrane domain as well as ABCC1. Susan P.C. Cole interconnects KEAP1, Cell sorting and Genetic screen in the investigation of issues within Multidrug Resistance Protein 1. The study incorporates disciplines such as Protein structure and Cell biology in addition to ATP-binding cassette transporter.
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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
S. P. C. Cole;G. Bhardwaj;J. H. Gerlach;J. E. Mackie.
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
Elaine M. Leslie;Roger G. Deeley;Susan P.C. Cole.
Toxicology and Applied Pharmacology (2005)
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
I. Leier;G. Jedlitschky;U. Buchholz;S. P. C. Cole.
Journal of Biological Chemistry (1994)
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.
Susan P. C. Cole;Kathryn E. Sparks;Karen Fraser;Douglas W. Loe.
Cancer Research (1994)
Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
Roger G. Deeley;Christopher Westlake;Susan P. C. Cole.
Physiological Reviews (2006)
Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.
Caroline E. Grant;Gunnar Valdimarsson;David R. Hipfner;Kurt C. Almquist.
Cancer Research (1994)
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport.
Douglas W. Loe;Kurt C. Almquist;Roger G. Deeley;Susan P.C. Cole.
Journal of Biological Chemistry (1996)
(Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) The MRP-Related and BCRP / ABCG2 Multidrug Resistance Proteins: Biology, Substrate Specificity and Regulation
A. Haimeur;G. Conseil;R. G. Deeley;S. P.C. Cole.
Current Drug Metabolism (2004)
Structural, mechanistic and clinical aspects of MRP1.
David R Hipfner;Roger G Deeley;Susan P.C Cole.
Biochimica et Biophysica Acta (1999)
Biology of the multidrug resistance-associated protein, MRP
D.W. Loe;R.G. Deeley;S.P.C. Cole.
European Journal of Cancer (1996)
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