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Susan P. C. Cole

Susan P. C. Cole

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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
34767
World Ranking
2298
National Ranking
66

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

Susan P. C. Cole is affiliated with Queen's University in Canada. Their research spans multiple fields within biomedicine, focusing primarily on Medicine and Biochemistry, Genetics and Molecular Biology. Their work intersects areas such as Oncology, Molecular Biology, Pulmonary and Respiratory Medicine, Nutrition and Dietetics, and Cell Biology.

The scientist has contributed to topics including drug transport and resistance mechanisms, trace elements in health, cystic fibrosis research advances, pharmacological effects and toxicity studies, Hippo pathway signaling and YAP/TAZ, cancer-related gene regulation, and prostate cancer treatment and research.

Frequent co-authors in their publications include Gwenaëlle Conseil, Naoto Soya, Haijin Xu, Ariel Roldán, and Zhengrong Yang.

Publications by Susan P. C. Cole span respected journals such as the International Journal of Molecular Sciences, Cancer Cell, The Oncologist, Nature Communications, and FEBS Journal. The following are some of their recent papers:

  • Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity, 2021, Cancer Cell
  • EMA Review of Daunorubicin and Cytarabine Encapsulated in Liposomes (Vyxeos, CPX-351) for the Treatment of Adults with Newly Diagnosed, Therapy-Related Acute Myeloid Leukemia or Acute Myeloid Leukemia with Myelodysplasia-Related Changes, 2020, The Oncologist
  • Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling, 2023, Nature Communications
  • GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators, 2022, FEBS Journal
  • Mutagenic Analysis of the Putative ABCC6 Substrate-Binding Cavity Using a New Homology Model, 2021, International Journal of Molecular Sciences

Best Publications

  • Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

    S. P. C. Cole;G. Bhardwaj;J. H. Gerlach;J. E. Mackie

  • Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

    Elaine M. Leslie;Roger G. Deeley;Susan P.C. Cole

  • The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

    I. Leier;G. Jedlitschky;U. Buchholz;S. P. C. Cole

  • Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

    Susan P. C. Cole;Kathryn E. Sparks;Karen Fraser;Douglas W. Loe

  • Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins

    Roger G. Deeley;Christopher Westlake;Susan P. C. Cole

  • Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

    Caroline E. Grant;Gunnar Valdimarsson;David R. Hipfner;Kurt C. Almquist

  • Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

    Douglas W. Loe;Kurt C. Almquist;Roger G. Deeley;Susan P.C. Cole

  • The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation.

    A. Haimeur;G. Conseil;R. G. Deeley;S. P.C. Cole

  • Biology of the multidrug resistance-associated protein, MRP

    D.W. Loe;R.G. Deeley;S.P.C. Cole

  • Structural, mechanistic and clinical aspects of MRP1.

    David R Hipfner;Roger G Deeley;Susan P.C Cole

  • Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione.

    Douglas W. Loe;Roger G. Deeley;Susan P. C. Cole

  • Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines.

    Douglas D. Ross;Weidong Yang;Lynne V. Abruzzo;William S. Dalton

  • MULTIDRUG RESISTANCE MEDIATED BY THE ATP-BINDING CASSETTE TRANSPORTER PROTEIN MRP

    Susan P.C. Cole;Roger G. Deeley

  • Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

    Elaine M Leslie;Roger G Deeley;Susan P.C Cole

  • Multidrug Resistance in a Human Small Cell Lung Cancer Cell Line Selected in Adriamycin

    Shelagh E. L. Mirski;James H. Gerlach;Susan P. C. Cole

  • Rapid chemosensitivity testing of human lung tumor cells using the MTT assay.

    S. P. C. Cole

  • Transport of glutathione and glutathione conjugates by MRP1

    Susan P.C. Cole;Roger G. Deeley

  • ABC proteins : from bacteria to man

    I. Barry Holland;Susan P. C. Cole;Karl Kuchler;Christopher F. Higgins

  • ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

    Inka Leier;Gabriele Jedlitschky;Ulrike Buchholz

  • Targeting Multidrug Resistance Protein 1 (MRP1, ABCC1): Past, Present, and Future

    Susan P.C. Cole

Frequent Co-Authors

Roger G. Deeley
Roger G. Deeley Queen's University
Thomas M. Grogan
Thomas M. Grogan Roche (Switzerland)
Michael Lohoff
Michael Lohoff Philipp University of Marburg
Michael C. Baird
Michael C. Baird Queen's University
Dietrich Keppler
Dietrich Keppler German Cancer Research Center
Maxwell Sehested
Maxwell Sehested Rigshospitalet
Dieter Schrenk
Dieter Schrenk Technical University of Kaiserslautern
John D. Schuetz
John D. Schuetz St. Jude Children's Research Hospital
Virginia K. Walker
Virginia K. Walker Queen's University
David F. Callen
David F. Callen University of Adelaide

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