D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 87 Citations 31,926 226 World Ranking 1278 National Ranking 32

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Susan P.C. Cole mostly deals with Biochemistry, Multidrug Resistance Protein 1, Multiple drug resistance, Glutathione and ATP-binding cassette transporter. Susan P.C. Cole applies her multidisciplinary studies on Biochemistry and Leukotriene C4 in her research. Her Multidrug Resistance Protein 1 study incorporates themes from ATPase, Organic anion, Glutathione transport, ABCC1 and Stereochemistry.

The various areas that Susan P.C. Cole examines in her ABCC1 study include Molecular biology, Multidrug Resistance-Associated Proteins and Organic anion transport. Her Multiple drug resistance research includes elements of Immunology, Cell culture, Transfection and Cancer research. Her ATP-binding cassette transporter study integrates concerns from other disciplines, such as Transport protein, P-glycoprotein and Membrane protein.

Her most cited work include:

  • Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line (2644 citations)
  • Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense (1079 citations)
  • The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. (747 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Biochemistry, Molecular biology, Multidrug Resistance Protein 1, Cell culture and Multiple drug resistance. Her Biochemistry and ATP-binding cassette transporter, Glutathione, Transmembrane domain, Transporter and Amino acid investigations all form part of her Biochemistry research activities. Susan P.C. Cole has included themes like Messenger RNA, Gene, Transfection and Epitope, Antibody in her Molecular biology study.

As a part of the same scientific study, Susan P.C. Cole usually deals with the Multidrug Resistance Protein 1, concentrating on ABCC1 and frequently concerns with Efflux. Her study in Cell culture is interdisciplinary in nature, drawing from both Cell, Cancer research, Immunology, Antigen and Monoclonal antibody. Within one scientific family, Susan P.C. Cole focuses on topics pertaining to Etoposide under Multiple drug resistance, and may sometimes address concerns connected to Topoisomerase.

She most often published in these fields:

  • Biochemistry (52.76%)
  • Molecular biology (33.07%)
  • Multidrug Resistance Protein 1 (26.38%)

What were the highlights of her more recent work (between 2007-2021)?

  • Biochemistry (52.76%)
  • Multidrug Resistance Protein 1 (26.38%)
  • ATP-binding cassette transporter (19.69%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are Biochemistry, Multidrug Resistance Protein 1, ATP-binding cassette transporter, Transporter and ABCC1. Her study in Organic anion transport, Transmembrane domain, Multidrug Resistance-Associated Proteins, Multidrug resistance-associated protein 2 and Mutant are all subfields of Biochemistry. Her research integrates issues of Transport protein, Glutathione and Single-nucleotide polymorphism in her study of Multidrug Resistance Protein 1.

Her work on ABCC4 as part of her general ATP-binding cassette transporter study is frequently connected to Leukotriene C4, thereby bridging the divide between different branches of science. Her Transporter research integrates issues from Cytoplasm, In vitro and In vivo. Her work carried out in the field of ABCC1 brings together such families of science as SNP, Cancer research, Abcg2, Immunology and Pharmacogenetics.

Between 2007 and 2021, her most popular works were:

  • Targeting Multidrug Resistance Protein 1 (MRP1, ABCC1): Past, Present, and Future (163 citations)
  • Mammalian multidrug-resistance proteins (MRPs). (147 citations)
  • Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter. (143 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Susan P.C. Cole mainly focuses on Biochemistry, Transporter, ABCC1, Multidrug Resistance Protein 1 and ATP-binding cassette transporter. Her study in Efflux and Drug metabolism is done as part of Biochemistry. In her study, Multiple drug resistance and Xenobiotic is inextricably linked to Multidrug Resistance-Associated Proteins, which falls within the broad field of Efflux.

Her studies deal with areas such as P-glycoprotein and Transmembrane domain as well as ABCC1. Susan P.C. Cole interconnects KEAP1, Cell sorting and Genetic screen in the investigation of issues within Multidrug Resistance Protein 1. The study incorporates disciplines such as Protein structure and Cell biology in addition to ATP-binding cassette transporter.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

S. P. C. Cole;G. Bhardwaj;J. H. Gerlach;J. E. Mackie.
Science (1992)

3986 Citations

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

Elaine M. Leslie;Roger G. Deeley;Susan P.C. Cole.
Toxicology and Applied Pharmacology (2005)

1537 Citations

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

I. Leier;G. Jedlitschky;U. Buchholz;S. P. C. Cole.
Journal of Biological Chemistry (1994)

1026 Citations

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

Susan P. C. Cole;Kathryn E. Sparks;Karen Fraser;Douglas W. Loe.
Cancer Research (1994)

1020 Citations

Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins

Roger G. Deeley;Christopher Westlake;Susan P. C. Cole.
Physiological Reviews (2006)

867 Citations

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

Caroline E. Grant;Gunnar Valdimarsson;David R. Hipfner;Kurt C. Almquist.
Cancer Research (1994)

808 Citations

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport.

Douglas W. Loe;Kurt C. Almquist;Roger G. Deeley;Susan P.C. Cole.
Journal of Biological Chemistry (1996)

800 Citations

(Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) The MRP-Related and BCRP / ABCG2 Multidrug Resistance Proteins: Biology, Substrate Specificity and Regulation

A. Haimeur;G. Conseil;R. G. Deeley;S. P.C. Cole.
Current Drug Metabolism (2004)

672 Citations

Structural, mechanistic and clinical aspects of MRP1.

David R Hipfner;Roger G Deeley;Susan P.C Cole.
Biochimica et Biophysica Acta (1999)

535 Citations

Biology of the multidrug resistance-associated protein, MRP

D.W. Loe;R.G. Deeley;S.P.C. Cole.
European Journal of Cancer (1996)

527 Citations

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