What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Biochemistry, Multidrug resistance-associated protein 2, Glutathione, Glucuronate and Molecular biology.
Efflux, Transport protein, Hepatocyte, ABCC1 and Adenosine triphosphate are among the areas of Biochemistry where the researcher is concentrating his efforts.
Dietrich Keppler combines subjects such as Apical membrane, Membrane glycoproteins, Membrane transport protein and Gene isoform with his study of Multidrug resistance-associated protein 2.
Dietrich Keppler interconnects Leukotriene C4, Vesicle and Membrane transport in the investigation of issues within Glutathione.
The Glucuronate study combines topics in areas such as Dubin–Johnson syndrome and Membrane protein.
His biological study spans a wide range of topics, including Lipopolysaccharide, Galactosamine, Pyrimidine, Ratón and Precursor cell.
His most cited work include:
- Membrane transporters in drug development. (2257 citations)
- The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. (747 citations)
- Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. (712 citations)
What are the main themes of his work throughout his whole career to date?
Dietrich Keppler mainly investigates Biochemistry, Multidrug resistance-associated protein 2, Molecular biology, Hepatocyte and Internal medicine.
His work deals with themes such as Leukotriene C4 and In vivo, which intersect with Biochemistry.
His Multidrug resistance-associated protein 2 research is multidisciplinary, incorporating perspectives in Transport protein, Epithelial polarity, Membrane transport protein, Apical membrane and Membrane glycoproteins.
The study incorporates disciplines such as Cholestasis, Secretion, Vesicle, Adenosine triphosphate and Cyclosporin a in addition to Hepatocyte.
His Internal medicine research incorporates elements of Endocrinology and Leukotriene E4.
His studies in Glutathione integrate themes in fields like Membrane, Membrane transport and Glycoprotein.
He most often published in these fields:
- Biochemistry (57.51%)
- Multidrug resistance-associated protein 2 (22.32%)
- Molecular biology (16.74%)
What were the highlights of his more recent work (between 2003-2017)?
- Biochemistry (57.51%)
- Efflux (6.87%)
- Multidrug resistance-associated protein 2 (22.32%)
In recent papers he was focusing on the following fields of study:
Dietrich Keppler focuses on Biochemistry, Efflux, Multidrug resistance-associated protein 2, Transporter and Apical membrane.
His Biochemistry study often links to related topics such as Bilirubin.
His studies examine the connections between Efflux and genetics, as well as such issues in Epithelial polarity, with regards to Transfection, Berberine and Organic cation transport.
His Multidrug resistance-associated protein 2 research is multidisciplinary, relying on both Organic anion transporter 1, Organic anion-transporting polypeptide, Cholestasis and Dubin–Johnson syndrome.
His research investigates the connection with Transporter and areas like Pharmacology which intersect with concerns in Drug discovery.
His research integrates issues of Concentrative nucleoside transporter, Cell biology, Equilibrative nucleoside transporter and Nucleoside in his study of Apical membrane.
Between 2003 and 2017, his most popular works were:
- Membrane transporters in drug development. (2257 citations)
- Expression and immunolocalization of the multidrug resistance proteins, MRP1–MRP6 (ABCC1–ABCC6), in human brain (306 citations)
- The apical conjugate efflux pump ABCC2 (MRP2) (293 citations)
In his most recent research, the most cited papers focused on:
Biochemistry, Multidrug resistance-associated protein 2, Efflux, Cholestasis and Pharmacology are his primary areas of study.
In his study, which falls under the umbrella issue of Biochemistry, ABCC4 is strongly linked to Blood–brain barrier.
His Multidrug resistance-associated protein 2 study combines topics in areas such as Glutathione and Glucuronate.
His study focuses on the intersection of Efflux and fields such as Apical membrane with connections in the field of Secretion, Epithelial polarity, Cell culture, Cell membrane and Dubin–Johnson syndrome.
In his study, Organic anion transporter 1, P-glycoprotein, Transport protein and Organic anion-transporting polypeptide is strongly linked to Bile Salt Export Pump, which falls under the umbrella field of Cholestasis.
His Pharmacology research includes elements of Transporter, SLC47A1 and Drug discovery.
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