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Christel Herold-Mende

Christel Herold-Mende

D-Index & Metrics

Medicine

D-Index
105
Citations
60073
World Ranking
6665
National Ranking
381

Overview

Christel Herold-Mende is affiliated with Heidelberg University in Germany. Their research contributions span multiple fields within medicine and molecular biology, with a strong focus on brain tumors and cancer biology.

The primary fields of study for Christel Herold-Mende include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of investigation cover specialized areas such as:

  • Molecular Biology
  • Genetics
  • Oncology
  • Cancer Research
  • Epidemiology

The main topics addressed in their scientific work are:

  • Glioma Diagnosis and Treatment
  • Meningioma and schwannoma management
  • Brain Metastases and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Immune cells in cancer
  • Protein Degradation and Inhibitors
  • Single-cell and spatial transcriptomics

Frequently publishing in specific venues, Christel Herold-Mende has appeared most often in:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Acta Neuropathologica
  • Neuro-Oncology Advances

Several recent significant papers include:

  • CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas, 2020, Acta Neuropathologica
  • Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology, 2020, Acta Neuropathologica
  • Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated, 2021, Zurich Open Repository and Archive (University of Zurich)
  • The genomic and transcriptional landscape of primary central nervous system lymphoma, 2022, Nature Communications
  • Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas, 2021, Cancer Discovery

Christel Herold-Mende has collaborated extensively with other researchers. Frequent co-authors include:

  • Andreas von Deimling
  • Felix Sahm
  • Andreas Unterberg
  • Wolfgang Wick
  • Rolf Warta

Best Publications

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • DNA methylation-based classification of central nervous system tumours

    David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

    Dominik Sturm;Hendrik Witt;Hendrik Witt;Volker Hovestadt;Dong Anh Khuong-Quang

  • Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

    Genevieve Schindler;David Capper;David Capper;Jochen Meyer;Wibke Janzarik

  • Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

    Christian Hartmann;Christian Hartmann;Jochen Meyer;Jörg Balss;David Capper

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • The whole-genome landscape of medulloblastoma subtypes

    Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt

  • New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

    Dominik Sturm;Dominik Sturm;Brent A. Orr;Umut H. Toprak;Volker Hovestadt

  • Dissecting the genomic complexity underlying medulloblastoma

    David T. W. Jones;Natalie Jäger;Marcel Kool;Thomas Zichner

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

    David T W Jones;Barbara Hutter;Natalie Jäger;Andrey Korshunov;Andrey Korshunov

  • Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

    Marcel Kool;David T.W. Jones;Natalie Jäger;Paul A. Northcott

  • Immunotherapy response assessment in neuro-oncology: a report of the RANO working group.

    Hideho Okada;Michael Weller;Raymond Huang;Gaetano Finocchiaro

  • DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

    Felix Sahm;Felix Sahm;Daniel Schrimpf;Damian Stichel;David T.W. Jones

  • Stem cell marker CD133 affects clinical outcome in glioma patients.

    Felix Zeppernick;Rezvan Ahmadi;Benito Campos;Christine Dictus

  • BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

    Stefan Pfister;Wibke G. Janzarik;Marc Remke;Aurélie Ernst

  • ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma.

    David E. Reuss;Felix Sahm;Felix Sahm;Daniel Schrimpf;Daniel Schrimpf;Benedikt Wiestler;Benedikt Wiestler

Frequent Co-Authors

Andreas von Deimling
Andreas von Deimling Heidelberg University
Felix Sahm
Felix Sahm University Hospital Heidelberg
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Andreas Unterberg
Andreas Unterberg Heidelberg University
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
David Capper
David Capper Charité - University Medicine Berlin
Andrey Korshunov
Andrey Korshunov German Cancer Research Center
David T. W. Jones
David T. W. Jones German Cancer Research Center
Christian Hartmann
Christian Hartmann Hannover Medical School
Guido Reifenberger
Guido Reifenberger Heinrich Heine University Düsseldorf

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