Peter Gierschik

What is he best known for?

The fields of study he is best known for:

• Gene
• Enzyme
• Amino acid

Peter Gierschik focuses on Biochemistry, GTPase, Transducin, MAPK/ERK pathway and RHOA. His research integrates issues of Molecular biology and Alpha in his study of Biochemistry. His Molecular biology study incorporates themes from Antiserum, Membrane and Pertussis toxin.

His GTPase research includes elements of Rhodopsin, Receptor and Nucleotide. Peter Gierschik combines subjects such as Cyclase and Membrane protein with his study of Transducin. His research in GTP' intersects with topics in Guanine and Effector.

His most cited work include:

• Antibodies directed against synthetic peptides distinguish between GTP-binding proteins in neutrophil and brain. (286 citations)
• The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI. (180 citations)
• Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles. (179 citations)

What are the main themes of his work throughout his whole career to date?

Peter Gierschik mainly focuses on Biochemistry, Cell biology, Molecular biology, G protein and Phospholipase C. His Transducin, Guanine, Nucleotide, G alpha subunit and GTP' investigations are all subjects of Biochemistry research. His work carried out in the field of GTP' brings together such families of science as Guanosine and Receptor.

His work deals with themes such as GTP-binding protein regulators, Alternative splicing, Pertussis toxin and Membrane, Membrane protein, which intersect with Molecular biology. Peter Gierschik focuses mostly in the field of G protein, narrowing it down to topics relating to Binding protein and, in certain cases, Recombinant DNA. His GTPase study deals with RHOA intersecting with RAC1 and MAPK/ERK pathway.

He most often published in these fields:

• Biochemistry (46.02%)
• Cell biology (31.86%)
• Molecular biology (28.32%)

What were the highlights of his more recent work (between 2011-2020)?

• Cell biology (31.86%)
• Signal transduction (14.16%)
• Internal medicine (9.73%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Signal transduction, Internal medicine, Endocrinology and Leptin receptor. His Cell biology course of study focuses on Chemokine and Actin and Degranulation. His study on Cell signaling, Heterotrimeric G protein and Phospholipase C is often connected to Rho GTPase activation as part of broader study in Signal transduction.

The various areas that Peter Gierschik examines in his Heterotrimeric G protein study include PDZ domain, Guanine nucleotide exchange factor, GTPase and Molecular Pharmacology. His biological study spans a wide range of topics, including CC chemokine receptors and Mesenchymal stem cell. His Leptin study combines topics in areas such as Hormone and Receptor.

Between 2011 and 2020, his most popular works were:

• Biologically Inactive Leptin and Early-Onset Extreme Obesity (109 citations)
• Discovery and characterization of an endogenous CXCR4 antagonist. (49 citations)
• Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene (39 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Enzyme
• Amino acid

His scientific interests lie mostly in Gene, Leptin receptor, Mutation, Endocrinology and Leptin. Peter Gierschik has researched Gene in several fields, including Hypogonadotropic hypogonadism and Innate immune system. The study incorporates disciplines such as Genetics, In silico and Homology in addition to Leptin receptor.

The concepts of his Mutation study are interwoven with issues in Cancer research, Mutant, Chronic lymphocytic leukemia, Ibrutinib and breakpoint cluster region. His work in Endocrinology addresses issues such as Internal medicine, which are connected to fields such as Aspartic acid. His studies deal with areas such as Receptor and Mutant protein as well as Leptin.