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Medicine

D-Index
90
Citations
29033
World Ranking
12226
National Ranking
6264

Overview

Bruce A. Lessey is affiliated with Wake Forest Baptist Medical Center in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with significant contributions to reproductive medicine and immunology.

They have published extensively on topics related to endometriosis and reproductive system conditions. Key areas of focus in their work include:

  • Endometriosis Research and Treatment
  • Reproductive System and Pregnancy
  • Uterine Myomas and Treatments
  • Estrogen and related hormone effects
  • Gynecological conditions and treatments
  • Ovarian function and disorders
  • Reproductive Biology and Fertility

Their frequent publication venues reflect a strong presence in specialized immunology and reproductive health journals, including:

  • UNC Libraries
  • Fertility and Sterility
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology

Some of their notable recent papers include:

  • Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2), 2022, The Lancet
  • Epigenetic Dysregulation in Endometriosis: Implications for Pathophysiology and Therapeutics, 2023, Endocrine Reviews
  • Estrogen mediates inflammatory role of mast cells in endometriosis pathophysiology, 2022, Frontiers in Immunology
  • ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation, 2020, Cell Reports
  • IL-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis, 2021, JCI Insight

Bruce A. Lessey has collaborated frequently with researchers such as Steven L. Young, Asgerally T. Fazleabas, Tae Hoon Kim, Jae-Wook Jeong, and Chandrakant Tayade. These co-authors highlight a collaborative network focused on reproductive health and immunological aspects of gynecological diseases.

Best Publications

  • Global Gene Profiling in Human Endometrium during the Window of Implantation

    L. C. Kao;S. Tulac;S. Lobo;B. Imani

  • Expression Profiling of Endometrium from Women with Endometriosis Reveals Candidate Genes for Disease-Based Implantation Failure and Infertility

    L. C. Kao;A. Germeyer;S. Tulac;S. Lobo

  • Gene Expression Analysis of Endometrium Reveals Progesterone Resistance and Candidate Susceptibility Genes in Women with Endometriosis

    Richard O. Burney;Said Talbi;Amy E. Hamilton;Kim Chi Vo

  • Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle.

    B A Lessey;L Damjanovich;C Coutifaris;A Castelbaum

  • Immunohistochemical Analysis of Human Uterine Estrogen and Progesterone Receptors Throughout the Menstrual Cycle

    Bruce A. Lessey;Allen P. Killam;Deborah A. Metzger;A. F. Haney

  • Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women

    S Talbi;A E Hamilton;K C Vo;S Tulac

  • ABERRANT INTEGRIN EXPRESSION IN THE ENDOMETRIUM OF WOMEN WITH ENDOMETRIOSIS

    Bruce A. Lessey;Arthur J. Castelbaum;Stephen W. Sawin;Clayton A. Buck

  • Placental apoptosis in preeclampsia.

    Alexander D. Allaire;Kelly A. Ballenger;Steven R. Wells;Michael J. McMahon

  • Leukemia inhibitory factor (LIF) and LIF receptor expression in human endometrium suggests a potential autocrine/paracrine function in regulating embryo implantation

    Emily B. Cullinan;Susan J. Abbondanzo;Patrick S. Anderson;Jeffrey W. Pollard

  • Changes in gene expression during the early to mid-luteal (receptive phase) transition in human endometrium detected by high-density microarray screening.

    Daniel D. Carson;Errin Lagow;Amantha Thathiah;Rania Al-Shami

  • Further characterization of endometrial integrins during the menstrual cycle and in pregnancy

    Bruce A. Lessey;Arthur J. Castelbaum;Arthur J. Castelbaum;Clayton A. Buck;Clayton A. Buck;Ying Lei;Ying Lei

  • Integrins as markers of uterine receptivity in women with primary unexplained infertility

    Bruce A. Lessey;Arthur J. Castelbaum;Arthur J. Castelbaum;Stephen W. Sawin;Stephen W. Sawin;Jinghai Sun;Jinghai Sun

  • Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist

    H. S. Taylor;L. C. Giudice;B. A. Lessey;M. S. Abrao

  • A critical analysis of the accuracy, reproducibility, and clinical utility of histologic endometrial dating in fertile women

    Michael J. Murray;William R. Meyer;Richard J. Zaino;Bruce A. Lessey

  • Endometrial stromal cells regulate epithelial cell growth in vitro: a new co-culture model

    Julia T. Arnold;David G. Kaufman;Markku Seppälä;Bruce A. Lessey

  • Hydrosalpinges adversely affect markers of endometrial receptivity.

    W R Meyer;A J Castelbaum;S Somkuti;A W Sagoskin

  • Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance

    Kathryn B. Horwitz;Mary B. Mockus;Bruce A. Lessey

  • Elevated Endometrial Androgen Receptor Expression in Women with Polycystic Ovarian Syndrome

    K.B.C. Apparao;Laurie P. Lovely;Yaoting Gui;Ruth A. Lininger

  • MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis.

    R.O. Burney;A.E. Hamilton;L. Aghajanova;K.C. Vo

  • What exactly is endometrial receptivity

    Bruce A. Lessey;Steven L. Young

Frequent Co-Authors

Asgerally T. Fazleabas
Asgerally T. Fazleabas Michigan State University
Linda C. Giudice
Linda C. Giudice University of California, San Francisco
Hugh S. Taylor
Hugh S. Taylor Yale University
Michael P. Diamond
Michael P. Diamond Augusta University
John P. Lydon
John P. Lydon Baylor College of Medicine
Robert N. Taylor
Robert N. Taylor University of Utah
Markku Seppälä
Markku Seppälä Helsinki University Hospital
Mitzi Nagarkatti
Mitzi Nagarkatti University of South Carolina
Clayton A. Buck
Clayton A. Buck The Wistar Institute
Francesco J. DeMayo
Francesco J. DeMayo National Institutes of Health

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