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Medicine

D-Index
93
Citations
27103
World Ranking
10999
National Ranking
5659

Overview

John P. Lydon is affiliated with Baylor College of Medicine in the United States and focuses on research encompassing medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work covers subfields including immunology, reproductive medicine, molecular biology, genetics, and obstetrics and gynecology.

The scientist has contributed extensively to topics related to the reproductive system and pregnancy, with notable coverage on endometriosis research and treatment, estrogen and related hormone effects, pregnancy and preeclampsia studies, reproductive biology and fertility, microRNA in disease regulation, and ovarian cancer diagnosis and treatment.

John P. Lydon's research output includes publications in numerous venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biology of Reproduction
  • Proceedings of the National Academy of Sciences
  • Nature Communications
  • The FASEB Journal

Frequent coauthors in their work include:

  • Francesco J. DeMayo
  • San-Pin Wu
  • Vineet K. Maurya
  • Ramakrishna Kommagani
  • Tianyuan Wang

Among recent papers authored or coauthored by John P. Lydon are:

  • "Progesterone Receptor Serves the Ovary as a Trigger of Ovulation and a Terminator of Inflammation," 2020, Cell Reports
  • "90 YEARS OF PROGESTERONE: New insights into progesterone receptor signaling in the endometrium required for embryo implantation," 2020, Journal of Molecular Endocrinology
  • "Targeting progesterone signaling prevents metastatic ovarian cancer," 2020, Proceedings of the National Academy of Sciences
  • "The autophagy protein, FIP200 (RB1CC1) mediates progesterone responses governing uterine receptivity and decidualization†," 2020, Biology of Reproduction
  • "Deficiency of PARP-1 and PARP-2 in the mouse uterus results in decidualization failure and pregnancy loss," 2021, Proceedings of the National Academy of Sciences

Best Publications

  • Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

    J. P. Lydon;F. J. Demayo;C. R. Funk;S. K. Mani

  • Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform

    Biserka Mulac-Jericevic;Robert A. Mullinax;Francesco J. DeMayo;John P. Lydon

  • Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform

    Biserka Mulac-Jericevic;John P. Lydon;Francesco J. DeMayo;Orla M. Conneely

  • A paracrine role for the epithelial progesterone receptor in mammary gland development

    Cathrin Brisken;Sissela Park;Tibor Vass;John P. Lydon

  • Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases

    R. L. Robker;D. L. Russell;L. L. Espey;J. P. Lydon

  • Reproductive functions of progesterone receptors.

    Orla M Conneely;Biserka Mulac-Jericevic;Francesco DeMayo;John P Lydon

  • The Antiproliferative Action of Progesterone in Uterine Epithelium Is Mediated by Hand2

    Quanxi Li;Athilakshmi Kannan;Francesco J. DeMayo;John P. Lydon

  • Cre-mediated recombination in cell lineages that express the progesterone receptor.

    Selma M. Soyal;Atish Mukherjee;Kevin Y.-S. Lee;Jie Li

  • Bmp2 Is Critical for the Murine Uterine Decidual Response

    Kevin Y. Lee;Jae-Wook Jeong;Jinrong Wang;Lijiang Ma

  • Reproductive phenotpes of the progesterone receptor null mutant mouse.

    John P. Lydon;Francesco J. DeMayo;Orla M. Conneely;Bert W. O'Malley

  • Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis.

    Sang Jun Han;Sung Yun Jung;San Pin Wu;Shannon M. Hawkins

  • Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms.

    Orla M. Conneely;Biserka Mulac-Jericevic;John P. Lydon

  • Reproductive functions of the progesterone receptor isoforms: lessons from knock-out mice

    Orla M. Conneely;Biserka Mulac-Jericevic;John P. Lydon;Francesco J. De Mayo

  • Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus

    Kevin Lee;JaeWook Jeong;Inseok Kwak;Cheng-Tai Yu

  • Progesterone receptors in reproduction: functional impact of the A and B isoforms

    Orla M Conneely;John P Lydon

  • Conditional Loss of Uterine Pten Unfailingly and Rapidly Induces Endometrial Cancer in Mice

    Takiko Daikoku;Yasushi Hirota;Susanne Tranguch;Ayesha R. Joshi

  • WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse

    Heather L. Franco;Daisy Dai;Kevin Y. Lee;Cory A. Rubel

  • Dopamine activation of an orphan of the steroid receptor superfamily.

    Ronan F. Power;John P. Lydon;Orla M. Conneely;Bert W. O'Malley

  • Murine Mammary Gland Carcinogenesis Is Critically Dependent on Progesterone Receptor Function

    John P. Lydon;Gouqing Ge;Francis S. Kittrell;Daniel Medina

  • Conditional deletion of MSX homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity

    Takiko Daikoku;Jeeyeon Cha;Xiaofei Sun;Susanne Tranguch

Frequent Co-Authors

Francesco J. DeMayo
Francesco J. DeMayo National Institutes of Health
Bert W. O'Malley
Bert W. O'Malley Baylor College of Medicine
Orla M. Conneely
Orla M. Conneely Baylor College of Medicine
Sophia Y. Tsai
Sophia Y. Tsai Baylor College of Medicine
Chad J. Creighton
Chad J. Creighton Baylor College of Medicine
Ming-Jer Tsai
Ming-Jer Tsai Baylor College of Medicine
Milan K. Bagchi
Milan K. Bagchi University of Illinois at Urbana-Champaign
Russell Broaddus
Russell Broaddus University of North Carolina at Chapel Hill
Thomas E. Spencer
Thomas E. Spencer University of Missouri
Paul S. Cooke
Paul S. Cooke University of Florida

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