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Klaus-Michael Debatin

Klaus-Michael Debatin

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Biology and Biochemistry
Germany
2023

D-Index & Metrics

Medicine

D-Index
117
Citations
68011
World Ranking
4131
National Ranking
227

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Klaus-Michael Debatin is affiliated with the University of Ulm in Germany and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans multiple subfields including molecular biology, immunology, infectious diseases, genetics, and neurology.

The scientist's recent published papers include:

  • Apoptotic cell death in disease-Current understanding of the NCCD, 2023, Cell Death and Differentiation
  • Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany, 2021, JAMA Pediatrics
  • Robust and durable serological response following pediatric SARS-CoV-2 infection, 2022, Nature Communications
  • Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose induces energy depletion and synergistic anti-cancer activity in glioblastoma, 2020, British Journal of Cancer
  • Natural Killer Cells Generated From Human Induced Pluripotent Stem Cells Mature to CD56brightCD16+NKp80+/-In-Vitro and Express KIR2DL2/DL3 and KIR3DL1, 2021, Frontiers in Immunology

Frequent co-authors of Klaus-Michael Debatin include:

  • Pamela Fischer-Posovszky
  • Aleš Janda
  • Eva-Maria Jacobsen
  • Mike-Andrew Westhoff
  • Felix Seyfried

They publish regularly in several journals, with the most frequent publication venues being:

  • Blood
  • Klinische Pädiatrie
  • Oncogene
  • Cancer Research
  • Leukemia

Main fields of study are Medicine and Biochemistry, Genetics and Molecular Biology, supported by a focus on subfields such as molecular biology, immunology, infectious diseases, genetics, and neurology.

The primary topics of their research include:

  • Acute Lymphoblastic Leukemia research
  • Neuroblastoma Research and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Cell death mechanisms and regulation
  • COVID-19 Clinical Research Studies
  • MicroRNA in disease regulation
  • Glioma Diagnosis and Treatment

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Two CD95 (APO-1/Fas) signaling pathways

    Carsten Scaffidi;Simone Fulda;Anu Srinivasan;Claudia Friesen

  • Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy.

    S. Fulda;Klaus-Michael Debatin

  • Monoclonal antibody-mediated tumor regression by induction of apoptosis

    Bernhard C. Trauth;Christiane Klas;Anke M.J. Peters;Siegfried Matzku

  • Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

    Jens Dhein;Henning Walczak;Caroline Bäumler;Klaus-Michael Debatin

  • Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

    F. Rieux-Laucat;F. Le Deist;C. Hivroz;I. A. G. Roberts

  • Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells.

    Claudia Friesen;Ingrid Herr;Ingrid Herr;Peter H. Krammer;Klaus Michael Debatin;Klaus Michael Debatin

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Cellular stress response and apoptosis in cancer therapy

    Ingrid Herr;Klaus-Michael Debatin

  • Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

    Simone Fulda;Wolfgang Wick;Michael Weller;Klaus Michael Debatin;Klaus Michael Debatin

  • Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

    F. Leithauser;J. Dhein;G. Mechtersheimer;K. Koretz

  • Death receptors in chemotherapy and cancer.

    Klaus Michael Debatin;Peter H. Krammer

  • The CD95 (APO-1/Fas) System Mediates Drug-induced Apoptosis in Neuroblastoma Cells

    Simone Fulda;Hauke Sieverts;Claudia Friesen;Ingrid Herr

  • Activation interferes with the APO-1 pathway in mature human T cells

    Christiane Klas;Klaus michael Debatin;Richard R. Jonker;Richard R. Jonker;Peter H. Krammer

  • Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation

    Wabitsch M;Brenner Re;Melzner I;Braun M

  • Apoptosis pathways in cancer and cancer therapy.

    Klaus-Michael Debatin

  • CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons.

    Ana Martin-Villalba;Ingrid Herr;Irmela Jeremias;Michael Hahne

  • Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer.

    Simone Fulda;Martin U Küfer;Eric Meyer;Frans van Valen

  • Chemotherapy: targeting the mitochondrial cell death pathway.

    Klaus-Michael Debatin;Delphine Poncet;Guido Kroemer

  • Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

    Simone Fulda;Eric Meyer;Klaus-Michael Debatin

Frequent Co-Authors

Simone Fulda
Simone Fulda Goethe University Frankfurt
Martin Wabitsch
Martin Wabitsch University of Ulm
Peter H. Krammer
Peter H. Krammer German Cancer Research Center
klaus schwarz
klaus schwarz University of Ulm
Irmela Jeremias
Irmela Jeremias Ludwig-Maximilians-Universität München
Dirk Reinhardt
Dirk Reinhardt University of Duisburg-Essen
Thomas F. E. Barth
Thomas F. E. Barth University of Ulm
Henning Walczak
Henning Walczak University College London
Marek Los
Marek Los Silesian University of Technology
Peter Møller
Peter Møller University of Copenhagen

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