World's Best Scientists 2026 revealed!
Curtis D. Klaassen

Curtis D. Klaassen

D-Index & Metrics

Medicine

D-Index
135
Citations
59193
World Ranking
2084
National Ranking
1180

Overview

Curtis D. Klaassen is affiliated with the University of Kansas in the United States. Their research encompasses multiple areas within medicine and environmental science, with a particular focus on dermatology, health toxicology, mutagenesis, plant science, food science, and oncology.

Their work includes numerous studies on the effects and risks of endocrine-disrupting chemicals and contact dermatitis and allergies. Other notable topics covered in their research include pesticide exposure and toxicity, agricultural safety and regulations, drug transport and resistance mechanisms, polymer science related to PVC, and carcinogens with genotoxicity assessment.

Frequently publishing in specialized scientific journals, Klaassen has contributed extensively to the following venues:

  • International Journal of Toxicology
  • Drug Metabolism and Disposition
  • PubMed
  • Toxicology and Applied Pharmacology
  • Xenobiotica

Their recent papers illustrate the breadth of their research interests, including:

  • Amended Safety Assessment of Parabens as Used in Cosmetics (2020, International Journal of Toxicology)
  • Molecular Regulation of Bile Acid Homeostasis (2021, Drug Metabolism and Disposition)
  • Expression of cytochrome P450 isozyme transcripts and activities in human livers (2020, Xenobiotica)
  • Suppressed farnesoid X receptor by iron overload in mice and humans potentiates iron-induced hepatotoxicity (2021, Hepatology)
  • Safety Assessment of Lecithin and Other Phosphoglycerides as Used in Cosmetics (2020, International Journal of Toxicology)

Klaassen collaborates frequently with several researchers in the field, including:

  • D. Belsito
  • Bart Heldreth
  • Wilma F. Bergfeld
  • Thomas J. Slaga
  • Paul W. Snyder

Their main contributions focus on interdisciplinary approaches blending toxicology, pharmacology, and environmental impacts on human health. Klaassen's work captures significant themes such as chemical safety in cosmetic products and fundamental biological processes like bile acid regulation and liver enzyme expression.

Best Publications

  • The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

    Jeffrey Leonard Staudinger;Jeffrey Leonard Staudinger;Bryan Goodwin;Stacey A. Jones;Diane Hawkins-Brown

  • Sulfation and sulfotransferases 5: the importance of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) in the regulation of sulfation.

    Curtis D. Klaassen;James W. Boles

  • Toxicology of cadmium

    P. L. Goering;M. P. Waalkes;C. D. Klaassen

  • Cadmium-induced hepatic and renal injury in chronically exposed rats: Likely role of hepatic cadmium-metallothionein in nephrotoxicity

    Robert E. Dudley;Lynda M. Gammal;Curtis D. Klaassen

  • Cadmium-Induced Apoptosis in Mouse Liver

    Sultan S.M. Habeebu;Jie Liu;Curtis D. Klaassen

  • Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway

    Jonathan M. Maher;Matthew Z. Dieter;Lauren M. Aleksunes;Angela L. Slitt;Angela L. Slitt

  • Introducing the "TCDD-inducible AhR-Nrf2 gene battery".

    Ronnie L. Yeager;Scott A. Reisman;Lauren M. Aleksunes;Curtis D. Klaassen

  • Coordinate Regulation of Xenobiotic and Bile Acid Homeostasis by Pregnane X Receptor

    Jeff Staudinger;Yaping Liu;Ajay Madan;Sultan Habeebu

  • Quantitative-profiling of bile acids and their conjugates in mouse liver, bile, plasma, and urine using LC-MS/MS

    Yazen Alnouti;Iván L. Csanaky;Curtis D. Klaassen

  • Beneficial role of Nrf2 in regulating NADPH generation and consumption.

    Kai Connie Wu;Julia Yue Cui;Curtis D. Klaassen

  • Increase in metallothionein produced by chemicals that induce oxidative stress.

    J.W. Bauman;J. Liu;Y.P. Liu;C.D. Klaassen

  • Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice

    Lauren M. Aleksunes;Curtis D. Klaassen

  • Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver.

    Jonathan M. Maher;Xingguo Cheng;Angela L. Slitt;Matthew Z. Dieter

  • Protective effect of metallothionein against the toxicity of cadmium and other metals(1).

    Jung D Park;Yaping Liu;Curtis D Klaassen

  • Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.

    Nathan J. Cherrington;Dylan P. Hartley;Ning Li;David R. Johnson

  • NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet

    Yuji Tanaka;Lauren M. Aleksunes;Ronnie L. Yeager;Maxwell A. Gyamfi

  • Tissue distribution and ontogeny of sulfotransferase enzymes in mice

    Yazen Alnouti;Curtis D. Klaassen

  • Intestinal absorption of cadmium is associated with divalent metal transporter 1 in rats.

    Jung D. Park;Nathan J. Cherrington;Curtis D. Klaassen

  • Tissue mRNA expression of the rat UDP-glucuronosyltransferase gene family.

    M. K. Shelby;N. J. Cherrington;N. R. Vansell;N. R. Vansell;Curtis D. Klaassen

  • Gender-specific and developmental influences on the expression of rat organic anion transporters.

    Susan C. N. Buist;Nathan J. Cherrington;Supratim Choudhuri;Dylan P. Hartley

Frequent Co-Authors

Lauren M. Aleksunes
Lauren M. Aleksunes Rutgers, The State University of New Jersey
daniel c liebler
daniel c liebler Vanderbilt University
Thomas J. Slaga
Thomas J. Slaga The University of Texas Health Science Center at San Antonio
Michael P. Waalkes
Michael P. Waalkes National Institutes of Health
Jie Liu
Jie Liu National Institutes of Health
Glen K. Andrews
Glen K. Andrews University of Kansas
Yu-Jui Yvonne Wan
Yu-Jui Yvonne Wan University of California, Davis
George L. Scheffer
George L. Scheffer VU University Medical Center
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Andrew Parkinson
Andrew Parkinson University of Kansas

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring alternative online degrees in healthcare can expand career options beyond traditional medical school paths. Many students consider healthcare administration, nursing, and pharmacy programs for their flexible study modes and broad career prospects.

For those interested in healthcare management, seeking the cheapest mha programs online is a practical way to earn a Master’s in Healthcare Administration without excessive financial burden. Similarly, students can review a range of cheap mha programs to find an option that fits their budget.

Advanced nursing degrees are also in high demand and offer flexible online formats. Prospective nurse leaders may find dnp online programs cheap so they can progress their careers while managing costs.

For those aiming for a pharmacy career, numerous online pharmacy school programs provide accredited paths to enter this growing field, often with affordable tuition models.

Exploring these online healthcare degrees can create new career pathways, deliver flexibility, and help manage educational expenses as you pursue a future in medicine and health services.

Best Scientists Citing Curtis D. Klaassen

Trending Scientists