World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
88
Citations
27583
World Ranking
13189
National Ranking
505

George L. Scheffer publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where George L. Scheffer sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 190 publications — 2nd percentile

2% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

George L. Scheffer D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where George L. Scheffer sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 88 D-Index — 36th percentile

36% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

George L. Scheffer was affiliated with the VU University Medical Center in the Netherlands. Their work spanned multiple interconnected fields within medicine, primarily focusing on oncology, radiology, nuclear medicine and imaging, and immunology.

Their research contributions consisted of studies in areas such as CAR-T cell therapy, monoclonal and polyclonal antibodies, and immune cell function and interaction.

  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Immune Cell Function and Interaction

Among their recent published papers were:

  • "A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies" (2020), published in Cancer Immunology Research
  • "PD-L1 directed bispecific Vδ2-T cell engager combines lysis of PD-L1 expressing tumor cells with PD-1 immune checkpoint inhibition and modulation of the tumor immune microenvironment" (2025), published in Journal for ImmunoTherapy of Cancer

Their frequent co-authors included:

  • Tanja D. de Gruijl
  • Hans van Vliet
  • Iris de Weerdt
  • Roeland Lameris
  • Jana Vree

George L. Scheffer's research appeared primarily in the following publication venues:

  • Cancer Immunology Research
  • Journal for ImmunoTherapy of Cancer

The overall body of work reflected interdisciplinary approaches engaging with immune mechanisms in cancer therapy, particularly emphasizing cellular immunotherapy and antibody-mediated modulation.

Best Publications

  • Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

    M Maliepaard;G L Scheffer;I F Faneyte;M A van Gastelen

  • Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

    M. Kool;M. De Haas;G. L. Scheffer;R. J. Scheper

  • Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene.

    Coen C. Paulusma;Piter J. Bosma;Guido J. R. Zaman;Conny T. M. Bakker

  • The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

    Johan W. Jonker;Marije Buitelaar;Els Wagenaar;Martin A. van der Valk

  • The drug resistance-related protein LRP is the human major vault protein

    George L. Scheffer;Peter L.J. Wijngaard;Marcel J. Flens;Miguel A. Izquierdo

  • Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance.

    R.J. Scheper;H.J. Broxterman;G.L. Scheffer;P. Kaaijk

  • MRP3, an organic anion transporter able to transport anti-cancer drugs

    M. Kool;M. van der Linden;M. de Haas;G. L. Scheffer

  • Tissue distribution of the multidrug resistance protein.

    M. J. Flens;G. J. R. Zaman;P. Van Der Valk;M. A. Izquierdo

  • A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome.

    C. C. Paulusma;M. Kool;P. J. Bosma;G. L. Scheffer

  • Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

    J Wijnholds;C A Mol;L van Deemter;M de Haas

  • The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood☆☆☆

    Emmanuel Jacquemin;Olivier Bernard;Michelle Hadchouel;Danièle Cresteil

  • Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein

    Ruud Oerlemans;Niels E. Franke;Yehuda G. Assaraf;Jacqueline Cloos

  • Mrp4 confers resistance to topotecan and protects the brain from chemotherapy.

    Markos Leggas;Masashi Adachi;George L. Scheffer;Daxi Sun

  • Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

    Jan Wijnholds;Elizabeth C.M. de Lange;George L. Scheffer;Dirk-Jan van den Berg

  • Immunochemical Detection of the Multidrug Resistance-associated Protein MRP in Human Multidrug-resistant Tumor Cells by Monoclonal Antibodies

    Marcel J. Flens;Miguel A. Izquierdo;George L. Scheffer;Jan M. Fritz

  • Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material.

    Julio E. Diestra;George L. Scheffer;Isabel Català;Marc Maliepaard

  • Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway

    Jonathan M. Maher;Matthew Z. Dieter;Lauren M. Aleksunes;Angela L. Slitt;Angela L. Slitt

  • Tissue Distribution and Induction of Human Multidrug Resistant Protein 3

    George L Scheffer;Marcel Kool;Marcel de Haas;J Marleen L de Vree

  • Overexpression of the major vault transporter protein lung-resistance protein predicts treatment outcome in acute myeloid leukemia

    Alan F. List;Catherine S. Spier;Thomas M. Grogan;Cynthia Johnson

  • Drug resistance-associated marker LRP for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma

    M A Izquierdo;A G van der Zee;J B Vermorken;P van der Valk

Frequent Co-Authors

Rik J. Scheper
Rik J. Scheper Amsterdam University Medical Centers
Gerrit Jansen
Gerrit Jansen Amsterdam UMC
Tanja D. de Gruijl
Tanja D. de Gruijl Vrije Universiteit Amsterdam
Yehuda G. Assaraf
Yehuda G. Assaraf Technion – Israel Institute of Technology
Godefridus J. Peters
Godefridus J. Peters Gdańsk Medical University
Willem F. Lems
Willem F. Lems Vrije Universiteit Amsterdam
Piet Borst
Piet Borst Antoni van Leeuwenhoek Hospital
Paul van der Valk
Paul van der Valk Vrije Universiteit Amsterdam
Lauren M. Aleksunes
Lauren M. Aleksunes Rutgers, The State University of New Jersey
Robert H. Shoemaker
Robert H. Shoemaker National Institutes of Health

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