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Medicine

D-Index
110
Citations
38411
World Ranking
5623
National Ranking
3027

Overview

James L. Boyer is affiliated with Yale University in the United States and has a primary research focus in Medicine, with a significant number of publications addressing Hepatology. Their expertise encompasses multiple subfields including Hepatology, Oncology, Epidemiology, Surgery, and Molecular Biology.

Their research covers a range of topics centered on liver health and disease, including:

  • Liver Disease Diagnosis and Treatment
  • Liver Diseases and Immunity
  • Drug Transport and Resistance Mechanisms
  • Pediatric Hepatobiliary Diseases and Treatments
  • Liver physiology and pathology
  • Gallbladder and Bile Duct Disorders
  • Liver Disease and Transplantation

They have contributed extensively to the scientific literature, with numerous papers published in prominent journals. Frequent venues for their work include:

  • Hepatology
  • Journal of Hepatology
  • Hepatology Communications
  • Cellular and Molecular Gastroenterology and Hepatology
  • JHEP Reports

Some of their recent notable publications are:

  • "Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids" (2021), published in Cell Stem Cell
  • "Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases" (2021), published in Hepatology
  • "Bile formation and secretion: An update" (2021), published in Journal of Hepatology
  • "The role of bile acids in cholestatic liver injury" (2021), published in Annals of Translational Medicine
  • "The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology" (2021), published in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Across these studies, topics such as bile formation, liver physiology, and mechanisms of liver injury are explored in detail.

Collaboration is a prominent aspect of their research, with frequent co-authors including:

  • Shi-Ying Cai
  • David N. Assis
  • Carol J. Soroka
  • Nan Zhao
  • Qiong Pan

Best Publications

  • Bile Salt Transporters: Molecular Characterization, Function, and Regulation

    Michael Trauner;James L. Boyer

  • Molecular Pathogenesis of Cholestasis

    Michael Trauner;Peter J. Meier;James L. Boyer

  • Bile formation and secretion.

    James L. Boyer

  • Primary Biliary Cholangitis: 2018 Practice Guidance From the American Association for the Study of Liver Diseases

    Keith D. Lindor;Christopher L. Bowlus;James Boyer;Cynthia Levy

  • The Prognostic Importance of Clinical and Histologic Features in Asymptomatic and Symptomatic Primary Biliary Cirrhosis

    Joseph Roll;James L. Boyer;Daniel Barry;Gerald Klatskin

  • The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

    Michael Trauner;Marco Arrese;Carol J. Soroka;Meenakshisundaram Ananthanarayanan

  • Mechanisms and regulation of bile secretion.

    Michael H. Nathanson;James L. Boyer

  • Drug‐induced cholestasis

    Manmeet S. Padda;Mayra Sanchez;Abbasi J. Akhtar;James L. Boyer

  • Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver.

    P J Meier;E S Sztul;A Reuben;J L Boyer

  • OSTα‐OSTβ: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

    Nazzareno Ballatori;Nazzareno Ballatori;Whitney V. Christian;Jin Young Lee;Paul A. Dawson

  • Caspase-3 Controls both Cytoplasmic and Nuclear Events Associated with Fas-Mediated Apoptosis in vivo

    Timothy S. Zheng;Stephan F. Schlosser;Tao Dao;Ravi Hingorani

  • A randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid in primary biliary cirrhosis

    Burton Combes;Robert L. Carithers;Willis C. Maddrey;Willis C. Maddrey;Danyu Lin

  • Peliosis Hepatis Associated with Androgenic-Anabolic Steroid Therapy: A Severe Form of Hepatic Injury

    Saeed A. Bagheri;James L. Boyer

  • Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors.

    M. Trauner;M. Arrese;Hyejin Lee;J. L. Boyer

  • Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTα-OSTβ in cholestasis in humans and rodents

    James L. Boyer;Michael Trauner;Albert Mennone;Carol J. Soroka

  • Comparative biochemistry of non-muscle actins.

    D J Gordon;J L Boyer;E D Korn

  • Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

    Carol J. Soroka;John M. Lee;Francesco Azzaroli;James L. Boyer

  • Fibrates and cholestasis

    Nisanne S. Ghonem;David N. Assis;James L. Boyer

  • Pattern of necrosis in acute viral hepatitis. Prognostic value of bridging (subacute hepatic necrosis).

    James L. Boyer;Gerald Klatskin

  • Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. Evidence for an electrogenic canalicular organic anion carrier.

    P J Meier;A St Meier-Abt;C Barrett;J L Boyer

Frequent Co-Authors

Nazzareno Ballatori
Nazzareno Ballatori University of Rochester
Michael Trauner
Michael Trauner Medical University of Vienna
Christian Trautwein
Christian Trautwein RWTH Aachen University
Ronald P.J. Oude Elferink
Ronald P.J. Oude Elferink University of Amsterdam
Hartmut Jaeschke
Hartmut Jaeschke University of Kansas
Jorge Rakela
Jorge Rakela Mayo Clinic
Tania Roskams
Tania Roskams KU Leuven
Michael H. Nathanson
Michael H. Nathanson Yale University
Guadalupe Garcia-Tsao
Guadalupe Garcia-Tsao Yale University
Gert Fricker
Gert Fricker Heidelberg University

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