D-Index & Metrics Best Publications
Nicholas F. LaRusso

Nicholas F. LaRusso

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 109 Citations 35,450 316 World Ranking 2520 National Ranking 1463

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Internal medicine, Primary sclerosing cholangitis, Gastroenterology, Cholangiocyte and Cell biology are his primary areas of study. The concepts of his Internal medicine study are interwoven with issues in Endocrinology and Surgery. His research in Primary sclerosing cholangitis intersects with topics in Primary biliary cirrhosis, Liver transplantation, Liver biopsy and Ulcerative colitis.

His Gastroenterology research is multidisciplinary, relying on both Cholangiography and Inflammatory bowel disease. His research integrates issues of Cell culture, Senescence, Biochemistry and Downregulation and upregulation in his study of Cholangiocyte. The various areas that Nicholas F. LaRusso examines in his Cell biology study include Receptor, Epithelium and Immune system.

His most cited work include:

  • The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs (759 citations)
  • Primary sclerosing cholangitis: Natural history, prognostic factors and survival analysis (527 citations)
  • Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. (517 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Internal medicine, Cell biology, Gastroenterology, Primary sclerosing cholangitis and Cholangiocyte. His research on Internal medicine frequently links to adjacent areas such as Endocrinology. His work deals with themes such as Cryptosporidium parvum and Biochemistry, which intersect with Cell biology.

His work carried out in the field of Gastroenterology brings together such families of science as Surgery and Inflammatory bowel disease. He combines subjects such as Primary biliary cirrhosis, Liver transplantation, Liver biopsy and Ulcerative colitis with his study of Primary sclerosing cholangitis. His Cholangiocyte study incorporates themes from Receptor, Bile duct, Cell culture and Immunology.

He most often published in these fields:

  • Internal medicine (44.57%)
  • Cell biology (22.62%)
  • Gastroenterology (23.53%)

What were the highlights of his more recent work (between 2012-2021)?

  • Internal medicine (44.57%)
  • Primary sclerosing cholangitis (22.62%)
  • Gastroenterology (23.53%)

In recent papers he was focusing on the following fields of study:

Nicholas F. LaRusso mostly deals with Internal medicine, Primary sclerosing cholangitis, Gastroenterology, Cell biology and Cholangiocyte. Internal medicine is closely attributed to Endocrinology in his research. Primary sclerosing cholangitis is a primary field of his research addressed under Pathology.

His Alkaline phosphatase research extends to Gastroenterology, which is thematically connected. His studies in Cell biology integrate themes in fields like Microvesicles and Cell growth. The study incorporates disciplines such as Tumor necrosis factor alpha, Cancer research, Senescence, Fibrosis and MAPK/ERK pathway in addition to Cholangiocyte.

Between 2012 and 2021, his most popular works were:

  • The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs (759 citations)
  • Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases. (153 citations)
  • Cholangiocyte senescence by way of N-Ras activation is a characteristic of primary sclerosing cholangitis (125 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

Nicholas F. LaRusso spends much of his time researching Cell biology, Cholangiocyte, Primary sclerosing cholangitis, Internal medicine and Immunology. The Cell biology study combines topics in areas such as Microvesicles and Biliary tract. His Cholangiocyte study combines topics in areas such as Fibrosis, Intrahepatic bile ducts and Bile acid.

His Primary sclerosing cholangitis research is under the purview of Pathology. His Internal medicine research includes elements of Gastroenterology and Endocrinology. He has researched Immunology in several fields, including Liver disease, Cell, Apoptosis and Cancer research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif.
Autophagy (2021)

8964 Citations

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi-Yi Zhu;Tamara Tchkonia;Tamar Pirtskhalava;Adam C Gower.
Aging Cell (2015)

1009 Citations

Primary sclerosing cholangitis: Natural history, prognostic factors and survival analysis

Russell H. Wiesner;Patricia M. Grambsch;E. Rolland Dickson;Jurgen Ludwig.
Hepatology (1989)

819 Citations

Clinicopathologic features of the syndrome of primary sclerosing cholangitis

Russell H. Wiesner;Nicholas F. LaRusso.
Gastroenterology (1980)

745 Citations

Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism.

Meeta Jaiswal;Nicholas F. LaRusso;Lawrence J. Burgart;Gregory J. Gores.
Cancer Research (2000)

744 Citations

Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with associated primary sclerosing cholangitis.

C Penna;R Dozois;W Tremaine;W Sandborn.
Gut (1996)

693 Citations

Cholangiocarcinoma complicating primary sclerosing cholangitis.

Charles B. Rosen;David M. Nagorney;Russell H. Wiesner;Robert J. Coffey.
Annals of Surgery (1991)

530 Citations

Current concepts. Primary sclerosing cholangitis.

LaRusso Nf;Wiesner Rh;Ludwig J;MacCarty Rl.
The New England Journal of Medicine (1984)

481 Citations

A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection

Xian Ming Chen;Patrick L. Splinter;Steven P. O'Hara;Nicholas F. LaRusso.
Journal of Biological Chemistry (2007)

471 Citations

The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis

Anand H Patel;Denise M Harnois;George G Klee;Nicholas F LaRusso.
The American Journal of Gastroenterology (2000)

467 Citations

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