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Biology and Biochemistry

D-Index
60
Citations
14815
World Ranking
11844
National Ranking
14

Research.com Recognitions

  • 2013 - Member of Academia Europaea

Overview

András Váradi is affiliated with the Hungarian Academy of Sciences in Hungary and specializes in the fields of Medicine as well as Biochemistry, Genetics and Molecular Biology. Their research spans several subfields, including Genetics, Rheumatology, Molecular Biology, Epidemiology, and Cell Biology.

Their academic contributions focus mainly on topics such as Dermatological and Skeletal Disorders, Heterotopic Ossification and Related Conditions, Inflammatory Myopathies and Dermatomyositis, Parathyroid Disorders and Treatments, Drug Transport and Resistance Mechanisms, Amyloidosis diagnosis and treatment, and Skin and Cellular Biology Research.

Among their recent publications are:

  • Structural and functional diversity calls for a new classification of ABC transporters, 2020, FEBS Letters
  • Oral supplementation of inorganic pyrophosphate in pseudoxanthoma elasticum, 2021, Experimental Dermatology
  • A koronavírus okozta COVID-19-pandémia. Korábbi tapasztalatok és tudományos evidenciák 2020. március végén, 2020, Orvosi Hetilap
  • Inorganic pyrophosphate is reduced in patients with systemic sclerosis, 2021, Lara D. Veeken
  • Plasma Level of Pyrophosphate Is Low in Pseudoxanthoma Elasticum Owing to Mutations in the ABCC6 Gene, but It Does Not Correlate with ABCC6 Genotype, 2023, Journal of Clinical Medicine

Frequent collaborators include:

  • Eszter Kozák
  • Krisztina Fülöp
  • Viola Pomozi
  • Natália Tőkési
  • Balázs Sarkadi

Their work has been published in venues such as:

  • FEBS Letters
  • Experimental Dermatology
  • Orvosi Hetilap
  • Lara D. Veeken
  • Journal of Clinical Medicine

Among recognized achievements, András Váradi was elected as a Member of Academia Europaea in 2013.

Best Publications

  • Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System

    Balázs Sarkadi;László Homolya;Gergely Szakács;András Váradi

  • An inventory of the human ABC proteins.

    Izabella Klein;Balázs Sarkadi;András Váradi

  • The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

    Gergely Szakács;András Váradi;Csilla Özvegy-Laczka;Balázs Sarkadi

  • Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.

    Csilla Özvegy;Thomas Litman;Gergely Szakács;Zoltán Nagy

  • Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain.

    Éva Bakos;Raymond Evers;Gergely Szakács;Gábor E. Tusnády

  • High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter

    Csilla Ozvegy-Laczka;Tamás Hegedus;György Várady;Olga Ujhelly

  • Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions.

    Éva Bakos;Raymond Evers;Emese Sinkó;András Váradi

  • ABCG2 - A transporter for all seasons

    Balázs Sarkadi;Csilla Özvegy-Laczka;Katalin Német;András Váradi

  • MDR3 P-glycoprotein, a Phosphatidylcholine Translocase, Transports Several Cytotoxic Drugs and Directly Interacts with Drugs as Judged by Interference with Nucleotide Trapping

    Alexander J. Smith;Ardy van Helvoort;Ardy van Helvoort;Gerrit van Meer;Katalin Szabó

  • Common evolutionary origin of the fibrin-binding structures of fibronectin and tissue-type plasminogen activator.

    László Bányai;András Váradi;László Patthy

  • Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

    Gábor E Tusnády;Éva Bakos;András Váradi;Balázs Sarkadi

  • Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators.

    Andrew C. Kruegel;Madalee M. Gassaway;Abhijeet Kapoor;András Váradi

  • The role of multidrug transporters in drug availability, metabolism and toxicity.

    Adrienn Bodó;Éva Bakos;Flóra Szeri;András Váradi

  • Multidrug Transporter ABCG2 Prevents Tumor Cell Death Induced by the Epidermal Growth Factor Receptor Inhibitor Iressa (ZD1839, Gefitinib)

    N. Barry Elkind;Zsófia Szentpétery;Ágota Apáti;Csilla Özvegy-Laczka

  • Loss of ATP-dependent Transport Activity in Pseudoxanthoma Elasticum-associated Mutants of Human ABCC6 (MRP6)

    Attila Iliás;Zsolt Urbán;Thomas L. Seidl;Olivier Le Saux

  • ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

    Robert S. Jansen;Suzanne Duijst;Sunny Mahakena;Daniela Sommer

  • Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.

    Csilla Özvegy;András Váradi;Balázs Sarkadi

  • Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate.

    László Homolya;András Váradi;Balázs Sarkadi

  • Membrane topology and glycosylation of the human multidrug resistance-associated protein.

    Éva Bakos;Tamás Hegedüs;Zsolt Holló;Ervin Welker

  • and directly interacts with drugs as judged by interference with nucleotide trapping

    Alexander J. Smith;Ardy van Helvoort;Gerrit van Meer;Katalin Szabó

Frequent Co-Authors

Balázs Sarkadi
Balázs Sarkadi TTK Research Centre for Natural Sciences
Jouni Uitto
Jouni Uitto Thomas Jefferson University
Piet Borst
Piet Borst Antoni van Leeuwenhoek Hospital
László Patthy
László Patthy Hungarian Academy of Sciences
Lajos Szente
Lajos Szente CycloLab (Hungary)
György Kéri
György Kéri Semmelweis University
Arthur A.B. Bergen
Arthur A.B. Bergen University of Amsterdam
Brian P. Sorrentino
Brian P. Sorrentino St. Jude Children's Research Hospital
István Simon
István Simon Hungarian Academy of Sciences
Michael Dean
Michael Dean National Institutes of Health

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