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Biology and Biochemistry
Hungary
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
11890
World Ranking
12592
National Ranking
15

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Hungary Leader Award
  • 2022 - Research.com Biology and Biochemistry in Hungary Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

László Patthy is affiliated with the Hungarian Academy of Sciences in Hungary. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a notable concentration in Molecular Biology, Cancer Research, and Genetics. Their work covers diverse subfields including Literature and Literary Theory as well as Endocrinology, Diabetes, and Metabolism.

The scientist's publication record includes significant papers spanning topics such as cancer genomics, evolutionary genetics, RNA and protein synthesis mechanisms, and mitochondrial function. Some of the recent papers authored or co-authored by László Patthy include:

  • Exon Shuffling Played a Decisive Role in the Evolution of the Genetic Toolkit for the Multicellular Body Plan of Metazoa (2021, Genes)
  • Use of signals of positive and negative selection to distinguish cancer genes and passenger genes (2021, eLife)
  • The SDHB Arg230His mutation causing familial paraganglioma alters glycolysis in a new Caenorhabditis elegans model (2020, Disease Models & Mechanisms)
  • Evolution of termination codons of proteins and the TAG-TGA paradox (2023, Scientific Reports)
  • Wnt Inhibitory Factor 1 Binds to and Inhibits the Activity of Sonic Hedgehog (2021, Cells)

Throughout their career, Patthy has contributed to research that touches upon various scientific topics, including:

  • Cancer Genomics and Diagnostics
  • Evolution and Genetic Dynamics
  • RNA and protein synthesis mechanisms
  • Genetics, Bioinformatics, and Biomedical Research
  • Hormonal Regulation and Hypertension
  • Cancer, Hypoxia, and Metabolism
  • Mitochondrial Function and Pathology

Their frequent coauthors include László Bányai, Mária Trexler, Krisztina Kerekes, Orsolya Csuka, and Éva Saskői, indicating collaborative work across multiple related research projects. Publication venues where Patthy has frequently appeared include Genes, Scientific Reports, eLife, Disease Models & Mechanisms, and Cells.

Patthy has been recognized as a Member of the European Molecular Biology Organization (EMBO), an affiliation reflecting their involvement in the broader molecular biology community.

Best Publications

  • Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules

    László Patthy

  • Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues.

    L Patthy;E L Smith

  • Genome evolution and the evolution of exon-shuffling--a review.

    László Patthy

  • The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator.

    N Behrendt;M Ploug;L Patthy;G Houen

  • Intron-dependent evolution: preferred types of exons and introns.

    László Patthy

  • Common evolutionary origin of the fibrin-binding structures of fibronectin and tissue-type plasminogen activator.

    László Bányai;András Váradi;László Patthy

  • Homology of a domain of the growth hormone/prolactin receptor family with type III modules of fibronectin.

    László Patthy

  • A deletion in the myostatin gene causes the compact (Cmpt) hypermuscular mutation in mice

    Gyula Szabó;Géza Dallmann;Géza Müller;László Patthy

  • Larger Genetic Differences Within Africans Than Between Africans and Eurasians

    Ning Yu;Feng Chi Chen;Feng Chi Chen;Satoshi Ota;Lynn B. Jorde

  • The NTR module: domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases.

    László Bányai;László Patthy

  • The implications of alternative splicing in the ENCODE protein complement

    Michael L. Tress;Pier Luigi Martelli;Adam Frankish;Gabrielle A. Reeves

  • Kringles: modules specialized for protein binding Homology of the gelatin-binding region of fibronectin with the kringle structures of proteases

    L. Patthy;M. Trexler;Z. Váli;L. Bányai

  • THE PAN MODULE : THE N-TERMINAL DOMAINS OF PLASMINOGEN AND HEPATOCYTE GROWTH FACTOR ARE HOMOLOGOUS WITH THE APPLE DOMAINS OF THE PREKALLIKREIN FAMILY AND WITH A NOVEL DOMAIN FOUND IN NUMEROUS NEMATODE PROTEINS

    Hedvig Tordai;László Bányai;László Patthy

  • Modular exchange principles in proteins

    László Patthy

  • Worldwide DNA sequence variation in a 10-kilobase noncoding region on human chromosome 22

    Zhongming Zhao;Li Jin;Yun Xin Fu;Michele Ramsay

  • Modular assembly of genes and the evolution of new functions.

    László Patthy

  • Detecting homology of distantly related proteins with consensus sequences.

    László Patthy

  • The SEA module: A new extracellular domain associated with O-glycosylation

    Peer Bork;Laszlo Patthy

  • Identification of functional arginine residues in ribonuclease A and lysozyme.

    Laszlo Patthy;Emil L. Smith

  • Functions of agrin and agrin-related proteins

    László Patthy;Károly Nikolics

Frequent Co-Authors

Niels Behrendt
Niels Behrendt Technical University of Denmark
Michael Ploug
Michael Ploug University of Copenhagen
András Váradi
András Váradi Hungarian Academy of Sciences
Gottfried Otting
Gottfried Otting Australian National University
Ettore Appella
Ettore Appella National Institutes of Health
Li Gan
Li Gan Cornell University
Antti Vaheri
Antti Vaheri University of Helsinki
Michèle Ramsay
Michèle Ramsay University of the Witwatersrand
Lynn B. Jorde
Lynn B. Jorde University of Utah
Wen-Hsiung Li
Wen-Hsiung Li Academia Sinica

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