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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12191
World Ranking
14364
National Ranking
160

Overview

Niels Behrendt is affiliated with the Technical University of Denmark in Denmark. Their research primarily spans the fields of Medicine as well as Biochemistry, Genetics, and Molecular Biology, with specific focus areas including Oncology, Immunology and Allergy, Pulmonary and Respiratory Medicine, Cancer Research, and Radiology, Nuclear Medicine and Imaging.

Their work engages deeply with topics such as Cell Adhesion Molecules Research, Protease and Inhibitor Mechanisms, Peptidase Inhibition and Analysis, HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, Radiopharmaceutical Chemistry and Applications, and Occupational and environmental lung diseases.

Frequent publication venues for their research include the Journal of Biological Chemistry, Cancer Research, International Journal of Molecular Sciences, Matrix Biology Plus, and Cellular and Molecular Life Sciences.

Some recent papers authored with coauthors on related projects are:

  • Osteosarcoma and Metastasis Associated Bone Degradation-A Tale of Osteoclast and Malignant Cell Cooperativity (2021, International Journal of Molecular Sciences)
  • Cellular uptake of collagens and implications for immune cell regulation in disease (2020, Cellular and Molecular Life Sciences)
  • Uncovering mediators of collagen degradation in the tumor microenvironment (2022, Matrix Biology Plus)
  • Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis (2020, Scientific Reports)
  • The collagen receptor uPARAP/Endo180 regulates collectins through unique structural elements in its FNII domain (2020, Journal of Biological Chemistry)

Frequent collaborators include Lars H. Engelholm, Henrik J. Jürgensen, Kirstine S. Nørregaard, Henrik Gårdsvoll, and Oliver Krigslund.

Best Publications

  • Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

    Ann L. Roldan;Maria Vittoria Cubellis;Maria Teresa Masucci;Niels Behrendt

  • Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol.

    M Ploug;E Rønne;N Behrendt;A L Jensen

  • Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor.

    V Ellis;N Behrendt;K Danø

  • Plasminogen activation and cancer

    Keld Danø;Niels Behrendt;Gunilla Høyer-Hansen;Morten Johnsen

  • Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants.

    R W Stephens;J Pöllänen;H Tapiovaara;K C Leung

  • Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis.

    Karin List;Christian C Haudenschild;Roman Szabo;WanJun Chen

  • The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants.

    N Behrendt;E Rønne;M Ploug;T Petri

  • A 55,000-60,000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification.

    Lars Søegaard Nielsen;G M Kellerman;N Behrendt;R Picone

  • The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion

    K. Danø;N. Behrendt;N. Brunner;V. Ellis

  • M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway

    Daniel H. Madsen;Daniel Leonard;Andrius Masedunskas;Amanda Moyer

  • The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator.

    N Behrendt;M Ploug;L Patthy;G Houen

  • Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors.

    Vincent John Ellis;T C Wun;N Behrendt;E Rønne

  • Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain.

    G Høyer-Hansen;E Rønne;H Solberg;N Behrendt

  • Structure, Function and Expression on Blood and Bone Marrow Cells of the Urokinase‐Type Plasminogen Activator Receptor, uPAR

    T. Plesner;N. Behrendt;M. Ploug

  • Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor.

    Ebbe Rønne;Niels Behrendt;Vincent Ellis;Michael Ploug

  • uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

    Lars H. Engelholm;Karin List;Karin List;Sarah Netzel-Arnett;Edna Cukierman

  • The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

    Gunilla Høyer-Hansen;Niels Behrendt;Michael Ploug;Keld Danø

  • Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate.

    R Picone;E L Kajtaniak;L S Nielsen;N Behrendt

  • A urokinase receptor-associated protein with specific collagen binding properties.

    Niels Behrendt;Ole N. Jensen;Lars H. Engelholm;Ejvind Mørtz

  • The Urokinase Receptor. Protein Structure and Role in Plasminogen Activation and Cancer Invasion

    K. Danø;N. Behrendt;B. Brunner;V. Ellis

Frequent Co-Authors

Keld Danø
Keld Danø Copenhagen University Hospital
Michael Ploug
Michael Ploug University of Copenhagen
Gunilla Høyer-Hansen
Gunilla Høyer-Hansen University of Copenhagen
Thomas H. Bugge
Thomas H. Bugge National Institutes of Health
Ettore Appella
Ettore Appella National Institutes of Health
Leif R. Lund
Leif R. Lund University of Copenhagen
László Patthy
László Patthy Hungarian Academy of Sciences
Boye Schnack Nielsen
Boye Schnack Nielsen Bioneer (Denmark)
Antti Vaheri
Antti Vaheri University of Helsinki
Francesco Blasi
Francesco Blasi University of Milan

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