Leif R. Lund

Overview

Best Publications

• Impaired wound healing in mice with a disrupted plasminogen gene.

  J Romer;T H Bugge;T H Bugge;C Pyke;L R Lund

  819
  Citations

• Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

  Ann L. Roldan;Maria Vittoria Cubellis;Maria Teresa Masucci;Niels Behrendt

  781
  Citations

• Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.

  Leif R. Lund;John Rømer;Nicole Thomasset;Helene Solberg

  753
  Citations

• Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones

  Michael T. Engsig;Qing-Jun Chen;Thiennu H. Vu;Anne-Cecilie Pedersen

  721
  Citations

• Plasminogen activator inhibitors: hormonally regulated serpins

  Peter A. Andreasen;Birgitte Georg;Leif R. Lund;Andrea Riccio

  583
  Citations

• Plasminogen activation and cancer

  Keld Danø;Niels Behrendt;Gunilla Høyer-Hansen;Morten Johnsen

  564
  Citations

• Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

  Morten Johnsen;Leif R Lund;John Rømer;Kasper Almholt

  516
  Citations

• The Plasminogen Activator Inhibitor PAI-1 Controls In Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin: Implications for Antiangiogenic Strategies

  Khalid Bajou;Véronique Masson;Robert D. Gerard;Petra M. Schmitt

  418
  Citations

• The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers.

  C. Pyke;J. Rømer;P. Kallunki;L. R. Lund

  398
  Citations

• Cancer invasion and tissue remodeling--cooperation of protease systems and cell types.

  Keld Danø;John Rømer;Boye S. Nielsen;Signe Bjørn

  383
  Citations

• Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis

  Bryony S. Wiseman;Mark D. Sternlicht;Leif R. Lund;Caroline M. Alexander

  360
  Citations

• Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.

  Andreas E. May;Sandip M. Kanse;Leif R. Lund;Roland H. Gisler

  353
  Citations

• Functional overlap between two classes of matrix‐degrading proteases in wound healing

  Leif R. Lund;John Rømer;Thomas H. Bugge;Boye S. Nielsen

  344
  Citations

• Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

  Melba Muñoz;Markus M. Heimesaat;Kerstin Danker;Daniela Struck

  341
  Citations

• One-chain urokinase-type plasminogen activator from human sarcoma cells is a proenzyme with little or no intrinsic activity.

  L C Petersen;L R Lund;L S Nielsen;K Danø

  338
  Citations

• Impaired wound contraction in stromelysin-1-deficient mice.

  Kelli M. Bullard;Leif Lund;John S. Mudgett;Theodore N. Mellin

  324
  Citations

• Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain.

  G Høyer-Hansen;E Rønne;H Solberg;N Behrendt

  316
  Citations

• Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts.

  L. R. Lund;A. Riccio;P. A. Andreasen;L. S. Nielsen

  299
  Citations

• Proteinases in bone resorption: obvious and less obvious roles

  Jean-Marie Delaissé;Michael T Engsig;Vincent Everts;Maria del Carmen Ovejero

  277
  Citations

• Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans.

  J. Grøndahl-Hansen;E. Ralfkiaer;L. T. Kirkeby;P. Kristensen

  247
  Citations