Leif R. Lund mostly deals with Molecular biology, Plasminogen activator, Matrix metalloproteinase, Stromal cell and Cell biology. The various areas that Leif R. Lund examines in his Molecular biology study include Urokinase receptor, Receptor, Integrin and Transforming growth factor. His biological study spans a wide range of topics, including Cell culture, Cycloheximide, Plasmin and Urokinase.
His work investigates the relationship between Urokinase and topics such as Diisopropyl fluorophosphate that intersect with problems in Proteases. In his study, Mammary gland, Cathepsin K, Osteoclast and Interstitial collagenase is inextricably linked to Endocrinology, which falls within the broad field of Matrix metalloproteinase. His study in Stromal cell is interdisciplinary in nature, drawing from both Cancer cell, Extracellular matrix, Cell type and Gelatinase.
The scientist’s investigation covers issues in Plasminogen activator, Molecular biology, Urokinase, Cell biology and Urokinase receptor. The Plasminogen activator study combines topics in areas such as Kallikrein, Cancer research, Angiogenesis and Plasmin. His studies in Molecular biology integrate themes in fields like Cell culture, Messenger RNA, In situ hybridization and Monoclonal antibody.
While the research belongs to areas of Urokinase, Leif R. Lund spends his time largely on the problem of Pathology, intersecting his research to questions surrounding Cancer and Adenocarcinoma. His work deals with themes such as Proteases, Epithelium, Stromal cell and Matrix metalloproteinase, which intersect with Cell biology. His Matrix metalloproteinase research is multidisciplinary, incorporating elements of Extracellular matrix, Endocrinology and Immunology.
Metastasis, Immunology, Cancer research, Plasminogen activator inhibitor-1 and Stromal cell are his primary areas of study. His Metastasis research includes themes of Urokinase receptor, Colorectal cancer, Breast cancer and Carcinogenesis. His research integrates issues of Gelatinase A and Gelatinase in his study of Immunology.
As part of his studies on Cancer research, Leif R. Lund frequently links adjacent subjects like Plasminogen activator. His Plasminogen activator inhibitor-1 research integrates issues from Urokinase, Vascular remodelling in the embryo, Pathology, Liver cancer and Mouse mammary tumor virus. The study incorporates disciplines such as Extracellular matrix, Genetically modified mouse, Primary tumor and Matrix metalloproteinase in addition to Stromal cell.
His primary areas of study are Ileitis, Metastasis, Urokinase receptor, Liver cancer and Pathology. Other disciplines of study, such as Gelatinase A, Interleukin, Gelatinase, Interleukin 22 and Immunology, are mixed together with his Ileitis studies. His Gelatinase A research incorporates themes from Interleukin 23, Interleukin 17 and Lamina propria.
His Metastasis study combines topics from a wide range of disciplines, such as Plasminogen activator inhibitor-1, Stromal cell, Colorectal cancer and Urokinase.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Impaired wound healing in mice with a disrupted plasminogen gene.
J Romer;T H Bugge;T H Bugge;C Pyke;L R Lund.
Nature Medicine (1996)
Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.
Leif R. Lund;John Rømer;Nicole Thomasset;Helene Solberg.
Development (1996)
Plasminogen activator inhibitors: hormonally regulated serpins
Peter A. Andreasen;Birgitte Georg;Leif R. Lund;Andrea Riccio.
Molecular and Cellular Endocrinology (1990)
Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation
Morten Johnsen;Leif R Lund;John Rømer;Kasper Almholt.
Current Opinion in Cell Biology (1998)
The Plasminogen Activator Inhibitor PAI-1 Controls In Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin: Implications for Antiangiogenic Strategies
Khalid Bajou;Véronique Masson;Robert D. Gerard;Petra M. Schmitt.
Journal of Cell Biology (2001)
The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers.
C. Pyke;J. Rømer;P. Kallunki;L. R. Lund.
American Journal of Pathology (1994)
Cancer invasion and tissue remodeling--cooperation of protease systems and cell types.
Keld Danø;John Rømer;Boye S. Nielsen;Signe Bjørn.
Apmis (1999)
Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.
Andreas E. May;Sandip M. Kanse;Leif R. Lund;Roland H. Gisler.
Journal of Experimental Medicine (1998)
Functional overlap between two classes of matrix‐degrading proteases in wound healing
Leif R. Lund;John Rømer;Thomas H. Bugge;Boye S. Nielsen.
The EMBO Journal (1999)
Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis
Bryony S. Wiseman;Mark D. Sternlicht;Leif R. Lund;Caroline M. Alexander.
Journal of Cell Biology (2003)
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