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Microbiology

D-Index
46
Citations
12607
World Ranking
4847
National Ranking
332

Overview

Michael Lohoff is affiliated with Philipp University of Marburg in Germany. Their research primarily focuses on fields related to medicine and immunology, with significant contributions to immunology and microbiology.

Their work covers several subfields of study, including:

  • Immunology
  • Infectious Diseases
  • Molecular Biology
  • Oncology
  • Public Health, Environmental and Occupational Health

Major topics in Michael Lohoff's research include:

  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • T-cell and B-cell Immunology
  • Acute Lymphoblastic Leukemia research
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation

Michael Lohoff has published in various scientific venues, with frequent publications in:

  • European Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism
  • Nature Microbiology
  • The EMBO Journal

Notable recent papers include:

  • Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function, 2020, Cell Metabolism
  • Induction of robust cellular and humoral immunity against SARS-CoV-2 after a third dose of BNT162b2 vaccine in previously unresponsive older adults, 2022, Nature Microbiology
  • PRMT1 promotes the tumor suppressor function of p14 ARF and is indicative for pancreatic cancer prognosis, 2021, The EMBO Journal
  • Deep phenotypical characterization of human CD3 + CD56 + T cells by mass cytometry, 2020, European Journal of Immunology
  • TMPRSS2, a novel host-directed drug target against SARS-CoV-2, 2022, Signal Transduction and Targeted Therapy

Frequent co-authors contributing extensively to collaborative research with Michael Lohoff include:

  • Henrik E. Mei
  • Dennis Das Gupta
  • Addi J. Romero-Olmedo
  • Axel Schulz
  • Daniel Staudenraus

Best Publications

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • An essential regulatory role for macrophage migration inhibitory factor in T-cell activation

    Michael Bacher;Christine N. Metz;Thierry Calandra;Katrin Mayer

  • The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4.

    Anne Brüstle;Sylvia Heink;Magdalena Huber;Christine Rosenplänter

  • Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells

    Valérie Staudt;Evita Bothur;Matthias Klein;Karen Lingnau

  • Glutathione Primes T Cell Metabolism for Inflammation

    Tak W. Mak;Tak W. Mak;Melanie Grusdat;Gordon S. Duncan;Catherine Dostert

  • IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype

    Magdalena Huber;Anne Brüstle;Katharina Reinhard;Anna Guralnik

  • Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo.

    Michael Lohoff;Michael Lohoff;David Ferrick;David Ferrick;Hans-Willi Mittrücker;Gordon S Duncan

  • Interleukin‐12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (Th1) but not on Th2 cells

    Tieno Germann;Maurice K. Gately;David S. Schoenhaut;Michael Lohoff

  • IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis

    Magdalena Huber;Sylvia Heink;Axel Pagenstecher;Katharina Reinhard

  • Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4.

    Michael Lohoff;Hans-Willi Mittrücker;Stefan Prechtl;Susi Bischof

  • A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity.

    Magdalena Huber;Sylvia Heink;Henrike Grothe;Anna Guralnik

  • Roles of interferon-regulatory factors in T-helper-cell differentiation

    Michael Lohoff;Tak W. Mak;Tak W. Mak

  • Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

    Thomas Kammertoens;Christian Friese;Christian Friese;Ainhoa Arina;Christian Idel

  • IRF4 at the crossroads of effector T-cell fate decision.

    Magdalena Huber;Michael Lohoff

  • IL-27 inhibits the development of regulatory T cells via STAT3

    Magdalena Huber;Vera Steinwald;Anna Guralnik;Anne Brüstle

  • IFN-γ Represses IL-4 Expression via IRF-1 and IRF-2

    Bernd Elser;Michael Lohoff;Sonja Kock;Marco Giaisi

  • Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype.

    Frank Sommer;Gerhard Faller;Peter Konturek;Thomas Kirchner

  • Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation

    Nadine Bollig;Anne Brüstle;Kerstin Kellner;Waltraud Ackermann

  • Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells.

    Michael Lohoff;Gordon S. Duncan;Gordon S. Duncan;David Ferrick;Hans-Willi Mittrücker

  • Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function.

    Henry Kurniawan;Davide G. Franchina;Luana Guerra;Lynn Bonetti

Frequent Co-Authors

Martin Röllinghoff
Martin Röllinghoff University of Erlangen-Nuremberg
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Christian Bogdan
Christian Bogdan University of Erlangen-Nuremberg
Tobias Bopp
Tobias Bopp Johannes Gutenberg University of Mainz
Werner Solbach
Werner Solbach University of Lübeck
Gordon S. Duncan
Gordon S. Duncan University Health Network
Edgar Schmitt
Edgar Schmitt Johannes Gutenberg University of Mainz
Andreas Radbruch
Andreas Radbruch German Rheumatism Research Centre
Hans-Willi Mittrücker
Hans-Willi Mittrücker Universität Hamburg

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