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Hans-Willi Mittrücker

Hans-Willi Mittrücker

D-Index & Metrics

Immunology

D-Index
67
Citations
14961
World Ranking
2683
National Ranking
178

Overview

Hans-Willi Mittrücker is affiliated with Universität Hamburg in Germany and has a research focus primarily in the fields of Immunology and Microbiology as well as Medicine. Their work encompasses several subfields including Immunology, Physiology, Pulmonary and Respiratory Medicine, Oncology, and Nephrology.

Their main research topics include:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Adenosine and Purinergic Signaling
  • Calcium signaling and nucleotide metabolism
  • Reproductive System and Pregnancy
  • Vasculitis and related conditions
  • Immunotherapy and Immune Responses

Mittrücker has published extensively, with a particular presence in notable scientific journals. Frequent publication venues include:

  • Journal of the American Society of Nephrology
  • Frontiers in Immunology
  • Nature Communications
  • Cells
  • Nature Immunology

Among the recent selected papers are:

  • Pathogen-induced tissue-resident memory T H 17 (T RM 17) cells amplify autoimmune kidney disease, 2020, Science Immunology
  • Vertically transferred maternal immune cells promote neonatal immunity against early life infections, 2021, Nature Communications
  • Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca 2+ signaling during T cell activation, 2021, Science Signaling
  • Short-term dietary changes can result in mucosal and systemic immune depression, 2023, Nature Immunology
  • P2X4 and P2X7 are essential players in basal T cell activity and Ca 2+ signaling milliseconds after T cell activation, 2022, Science Advances

Frequent co-authors collaborating with Mittrücker include:

  • Christian F. Krebs
  • Friedrich Koch-Nolte
  • Ulf Panzer
  • Hans-Joachim Paust
  • Tobias B. Huber

Best Publications

  • Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function

    Hans-Willi Mittrücker;Toshifumi Matsuyama;Alex Grossman;Thomas M. Kündig

  • Regulation of T Cell Receptor Signaling by Tyrosine Phosphatase SYP Association with CTLA-4

    Luc E. M. Marengère;Paul Waterhouse;Gordon S. Duncan;Hans-Willi Mittrücker

  • MSH2 deficient mice are viable and susceptible to lymphoid tumours.

    A.H. Reitmair;R. Schmits;A. Ewel;B. Bapat

  • Duration of TCR stimulation determines costimulatory requirement of T cells.

    Thomas M Kündig;Arda Shahinian;Kazuhiro Kawai;Hans-Willi Mittrücker

  • Immune response to infection with Salmonella typhimurium in mice.

    Hans-Willi Mittrücker;Stefan H. E. Kaufmann

  • Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of Mycobacterium tuberculosis

    Mischo Kursar;Markus Koch;Hans-Willi Mittrücker;Geraldine Nouailles

  • Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo.

    Michael Lohoff;Michael Lohoff;David Ferrick;David Ferrick;Hans-Willi Mittrücker;Gordon S Duncan

  • Heterogeneity in the differentiation and function of CD8⁺ T cells.

    Hans-Willi Mittrücker;Alexander Visekruna;Magdalena Huber

  • Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis

    Hans-Willi Mittrücker;Ulrich Steinhoff;Anne Köhler;Marion Krause

  • Systemic NKG2D Down-Regulation Impairs NK and CD8 T Cell Responses In Vivo

    Katrin Wiemann;Hans-Willi Mittrücker;Ute Feger;Stefan A. Welte

  • IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis

    Magdalena Huber;Sylvia Heink;Axel Pagenstecher;Katharina Reinhard

  • Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4.

    Michael Lohoff;Hans-Willi Mittrücker;Stefan Prechtl;Susi Bischof

  • A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity.

    Magdalena Huber;Sylvia Heink;Henrike Grothe;Anna Guralnik

  • The IL-23/Th17 Axis Contributes to Renal Injury in Experimental Glomerulonephritis

    Hans-Joachim Paust;Jan-Eric Turner;Oliver M. Steinmetz;Anett Peters

  • Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses.

    Mischo Kursar;Kerstin Bonhagen;Joachim Fensterle;Anne Köhler

  • Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE)

    Toshifumi Matsuyama;Alex Grossman;Hans willi Mittrücker;David P. Siderovski

  • Cutting Edge: Role of B Lymphocytes in Protective Immunity Against Salmonella typhimurium Infection

    Hans-Willi Mittrücker;Bärbel Raupach;Anne Köhler;Stefan H. E. Kaufmann

  • CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.

    Geraldine Nouailles;Anca Dorhoi;Markus Koch;Jens Zerrahn

  • CCR6 Recruits Regulatory T Cells and Th17 Cells to the Kidney in Glomerulonephritis

    Jan-Eric Turner;Hans-Joachim Paust;Oliver M. Steinmetz;Anett Peters

  • Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells.

    Michael Lohoff;Gordon S. Duncan;Gordon S. Duncan;David Ferrick;Hans-Willi Mittrücker

  • Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences.

    Chun Kim;Nadesan Gajendran;Hans-Willi Mittrücker;Matthias Weiwad

Frequent Co-Authors

Stefan H. E. Kaufmann
Stefan H. E. Kaufmann Max Planck Institute for Infection Biology
Ulf Panzer
Ulf Panzer Universität Hamburg
Rolf A.K. Stahl
Rolf A.K. Stahl Universität Hamburg
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Friedrich Koch-Nolte
Friedrich Koch-Nolte Universität Hamburg
Stefan Rose-John
Stefan Rose-John Kiel University
Petra C. Arck
Petra C. Arck Universität Hamburg
Friedrich Haag
Friedrich Haag Universität Hamburg
Thomas Kamradt
Thomas Kamradt Friedrich Schiller University Jena
Michael Lohoff
Michael Lohoff Philipp University of Marburg

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