H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 97 Citations 44,440 256 World Ranking 295 National Ranking 2
Medicine D-index 102 Citations 48,709 299 World Ranking 3354 National Ranking 145

Research.com Recognitions

Awards & Achievements

2018 - Robert L. Noble Prize, Canadian Cancer Society

2006 - Fellow of the Royal Society of Canada Academy of Science

2003 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • Cancer

Pamela S. Ohashi spends much of her time researching Immunology, T cell, Cell biology, Cytotoxic T cell and Molecular biology. The concepts of her T cell study are interwoven with issues in Cancer research, Ubiquitin ligase and Immune tolerance. Pamela S. Ohashi works in the field of Cell biology, namely Signal transduction.

Her Signal transduction study incorporates themes from Receptor and Protein kinase A. Her study in Cytotoxic T cell is interdisciplinary in nature, drawing from both CD8 and Immunotherapy. Her Molecular biology study integrates concerns from other disciplines, such as Lymphocyte proliferation, B-cell receptor, Transcription and Transcription factor.

Her most cited work include:

  • LPS/TLR4 signal transduction pathway (1721 citations)
  • LPS/TLR4 signal transduction pathway (1721 citations)
  • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand (1663 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in Immunology, Cell biology, T cell, Cytotoxic T cell and Immune system. In most of her Immunology studies, her work intersects topics such as Virology. Her Cell biology research is multidisciplinary, relying on both Acquired immune system, Receptor, Negative selection and T-cell receptor.

Pamela S. Ohashi combines subjects such as Cancer research, T lymphocyte and Immune tolerance with her study of T cell. The various areas that Pamela S. Ohashi examines in her Cytotoxic T cell study include Molecular biology and CD8. Her Immune system research is multidisciplinary, incorporating elements of Inflammation and Antibody.

She most often published in these fields:

  • Immunology (53.61%)
  • Cell biology (50.58%)
  • T cell (47.79%)

What were the highlights of her more recent work (between 2017-2021)?

  • Cancer research (30.54%)
  • Immune system (37.53%)
  • Internal medicine (9.56%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Cancer research, Immune system, Internal medicine, T cell and Oncology. Her research in Cancer research intersects with topics in Tumor microenvironment, Cancer, Immunotherapy, Antigen and Cytotoxic T cell. Her work carried out in the field of Immune system brings together such families of science as Phenotype and Cell biology.

She has included themes like T-cell receptor, T cell selection and Cytokine in her Cell biology study. Her T cell study frequently links to adjacent areas such as CD8. Her Cell research is multidisciplinary, incorporating perspectives in Antibody, Immunology, Autoimmunity, Lymphocytic choriomeningitis and Innate lymphoid cell.

Between 2017 and 2021, her most popular works were:

  • GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment (51 citations)
  • GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment (51 citations)
  • Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab (23 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cancer

Pamela S. Ohashi focuses on Cancer research, Immunotherapy, Immune system, Tumor microenvironment and Oncology. Pamela S. Ohashi has researched Cancer research in several fields, including Ovarian cancer, Transcription factor and Human leukocyte antigen, Antigen. Her Immunotherapy research integrates issues from Cytotoxic T cell and CD8.

Her work on Antitumor immunity as part of her general Cytotoxic T cell study is frequently connected to Context, thereby bridging the divide between different branches of science. Pamela S. Ohashi specializes in Immune system, namely T cell. Her biological study spans a wide range of topics, including Chemokine, Myeloid and Small interfering RNA.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

LPS/TLR4 signal transduction pathway

Yong-Chen Lu;Wen-Chen Yeh;Wen-Chen Yeh;Pamela S. Ohashi;Pamela S. Ohashi.
Cytokine (2008)

2526 Citations

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Young-Yun Kong;Ulrich Feige;Iidiko Sarosi;Brad Bolon.
Nature (1999)

2205 Citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection.

Klaus Pfeffer;Toshifumi Matsuyama;Thomas M. Kündig;Andrew Wakeham.
Cell (1993)

1960 Citations

Differential T cell costimulatory requirements in CD28-deficient mice

Arda Shahinian;Klaus Pfeffer;Kelvin P. Lee;Thomas M. Kündig.
Science (1993)

1520 Citations

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice.

Pamela S. Ohashi;Stephan Oehen;Kurt Buerki;Hanspeter Pircher.
Cell (1991)

1232 Citations

Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration

Takehiko Sasaki;Junko Irie-Sasaki;Russell G. Jones;Antonio J. Oliveira-dos-Santos.
Science (2000)

1225 Citations

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.

Jérôme Galon;Jérôme Galon;Jérôme Galon;Bernhard Mlecnik;Bernhard Mlecnik;Bernhard Mlecnik;Gabriela Bindea;Gabriela Bindea;Gabriela Bindea;Helen K. Angell;Helen K. Angell;Helen K. Angell.
The Journal of Pathology (2014)

1032 Citations

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

Nobutaka Suzuki;Shinobu Suzuki;Gordon S. Duncan;Douglas G. Millar.
Nature (2002)

992 Citations

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

H Suzuki;TM Kundig;C Furlonger;A Wakeham.
Science (1995)

938 Citations

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

Wen-Chen Yeh;Arda Shahinian;Daniel Speiser;Janine Kraunus.
Immunity (1997)

932 Citations

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