Hans Hengartner

Research.com Recognitions

• 2026 - Research.com Immunology in Switzerland Leader Award
• 2025 - Research.com Immunology in Switzerland Leader Award
• 2023 - Research.com Medicine in Switzerland Leader Award
• 2022 - Research.com Immunology in Switzerland Leader Award
• 2004 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

  David Kägi;Birgit Ledermann;Kurt Bürki;Peter Seiler

  2639
  Citations

• Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

  David Kägi;Françoise Vignaux;Birgit Ledermann;Kurt Bürki

  2066
  Citations

• A Primitive T Cell-Independent Mechanism of Intestinal Mucosal IgA Responses to Commensal Bacteria

  Andrew J. Macpherson;Dominique Gatto;Elizabeth Sainsbury;Gregory R. Harriman

  1576
  Citations

• Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice.

  Pamela S. Ohashi;Stephan Oehen;Kurt Buerki;Hanspeter Pircher

  1459
  Citations

• T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens.

  H. Robson MacDonald;Reto Schneider;Rosemary K. Lees;Rawleigh C. Howe

  1292
  Citations

• Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

  Hanspeter Pircher;Kurt Bürki;Rosemarie Lang;Hans Hengartner

  1224
  Citations

• Control of early viral and bacterial distribution and disease by natural antibodies.

  Adrian F. Ochsenbein;Thomas Fehr;Claudia Lutz;Mark Suter

  1097
  Citations

• Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

  Awen Gallimore;Ann Glithero;Andrew Godkin;Alain C. Tissot

  1086
  Citations

• The influence of antigen organization on B cell responsiveness

  Martin F. Bachmann;Urs Hoffmann Rohrer;Thomas M. Kündig;Kurt Bürki

  880
  Citations

• Molecular Mechanisms of Lymphocyte-Mediated Cytotoxicity and Their Role in Immunological Protection and Pathogenesis In Vivo

  David Kägi;Birgit Ledermann;Kurt Bürki;Rolf M. Zinkernagel

  871
  Citations

• Decreased tumor surveillance in perforin-deficient mice.

  M. F. Van Den Broek;D. Kagi;F. Ossendorp;R. Toes

  712
  Citations

• Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

  Hanspeter Pircher;Demetrius Moskophidis;Urs Rohrer;Kurt Bürki

  674
  Citations

• On immunological memory.

  Rolf M. Zinkernagel;Martin F. Bachmann;Thomas M. Kündig;Stephan Oehen

  662
  Citations

• Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

  Adrian F. Ochsenbein;Sophie Sierro;Bernhard Odermatt;Marcus Pericin

  647
  Citations

• Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity.

  Rolf M. Zinkernagel;Stephan Ehl;Peter Aichele;Stephan Oehen

  611
  Citations

• Immune responses in interleukin-2-deficient mice

  Thomas M. Kündig;Hubert Schorle;Martin F. Bachmann;Hans Hengartner

  603
  Citations

• Immune surveillance against a solid tumor fails because of immunological ignorance.

  Adrian F. Ochsenbein;Paul Klenerman;Urs Karrer;Burkhard Ludewig

  586
  Citations

• Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates.

  Manuel Battegay;Sue Cooper;Alana Althage;Jürg Bänziger

  574
  Citations

• FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

  Daniel D. Pinschewer;Adrian F. Ochsenbein;Bernhard Odermatt;Volker Brinkmann

  525
  Citations

• Structure and function of human perforin.

  Mathias G. Lichtenheld;Kristin J. Olsen;Ping Lu;David M. Lowrey

  461
  Citations