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Viacheslav O. Nikolaev

Viacheslav O. Nikolaev

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
16002
World Ranking
7815
National Ranking
575

Overview

Viacheslav O. Nikolaev is affiliated with Universität Hamburg in Germany and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their research predominantly focuses on molecular biology, cardiology and cardiovascular medicine, immunology, physiology, and endocrinology, diabetes, and metabolism.

The scientist's work covers a range of topics, with particular emphasis on receptor mechanisms and signaling, cardiac electrophysiology and arrhythmias, phosphodiesterase function and regulation, ion channel regulation and function, cardiovascular function and risk factors, nitric oxide and endothelin effects, and cardiomyopathy and myosin studies.

Frequent co-authors collaborating with Viacheslav O. Nikolaev include:

  • Hariharan Subramanian
  • Cristina E. Molina
  • Nadja I. Bork
  • Kirstie A. De Jong
  • Roberta Kurelić

They have published multiple papers in several journals. The most common venues for their publications are:

  • Circulation Research
  • Cells
  • Cardiovascular Research
  • Journal of Molecular and Cellular Cardiology
  • Nature Communications

Notable recent papers authored or co-authored by Nikolaev include:

  • Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation, 2020, Circulation Research
  • Skeletal muscle derived Musclin protects the heart during pathological overload, 2022, Nature Communications
  • cAMP Imaging at Ryanodine Receptors Reveals β 2 -Adrenoceptor Driven Arrhythmias, 2021, Circulation Research
  • AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR, 2021, Circulation Research
  • How Carvedilol activates β2-adrenoceptors, 2022, Nature Communications

Their research spans clinical and molecular aspects of cardiac function, focusing heavily on intracellular signaling pathways that contribute to cardiac electrophysiological behavior and arrhythmia development. This includes studying the roles of adrenergic receptors, calcium signaling, and related regulatory proteins within cardiac cells.

Overall, Viacheslav O. Nikolaev's body of work contributes to understanding the molecular mechanisms influencing heart function and disease, with active collaborations and significant publications in leading cardiovascular and molecular biology journals.

Best Publications

  • High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β2-Adrenergic Receptor/Gi–Dependent Manner A New Model of Takotsubo Cardiomyopathy

    Helen Paur;Peter T. Wright;Markus B. Sikkel;Matthew H. Tranter

  • Novel single chain cAMP sensors for receptor-induced signal propagation.

    Viacheslav O. Nikolaev;Moritz Bünemann;Lutz Hein;Annette Hannawacker

  • β2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

    Viacheslav O. Nikolaev;Viacheslav O. Nikolaev;Alexey Moshkov;Alexander R. Lyon;Michele Miragoli

  • Persistent cAMP-signals triggered by internalized G-protein-coupled receptors.

    Davide Calebiro;Viacheslav O. Nikolaev;Maria Cristina Gagliani;Tiziana de Filippis

  • Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte.

    Rachael P. Norris;William J. Ratzan;Marina Freudzon;Lisa M. Mehlmann

  • Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.

    Carlos Silvestre-Roig;Quinte Braster;Kanin Wichapong;Ernest Y. Lee

  • Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling.

    Viacheslav O. Nikolaev;Moritz Bünemann;Eva Schmitteckert;Martin J. Lohse

  • Sweet taste receptor expressed in pancreatic β-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

    Yuko Nakagawa;Masahiro Nagasawa;Satoko Yamada;Akemi Hara

  • Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging.

    Orie T. Shafer;Dong Jo Kim;Richard Dunbar-Yaffe;Viacheslav O. Nikolaev

  • Signaling by internalized G-protein-coupled receptors.

    Davide Calebiro;Viacheslav O. Nikolaev;Luca Persani;Martin J. Lohse

  • Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling.

    Jean-Pierre Vilardaga;Viacheslav O Nikolaev;Kristina Lorenz;Sébastien Ferrandon

  • FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

    Sebastian Börner;Frank Schwede;Angela Schlipp;Filip Berisha

  • Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes

    Jérôme Leroy;Aniella Abi-Gerges;Viacheslav O. Nikolaev;Wito Richter

  • Fluorescent sensors for rapid monitoring of intracellular cGMP.

    Viacheslav O Nikolaev;Stepan Gambaryan;Martin J Lohse

  • Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line

    Luis R. Landa;Mark Harbeck;Kelly Kaihara;Oleg Chepurny

  • Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation.

    Jordi Heijman;Jordi Heijman;Azinwi Phina Muna;Tina Veleva;Cristina E Molina;Cristina E Molina

  • Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.

    Marián Castro;Viacheslav O. Nikolaev;Dieter Palm;Martin J. Lohse

  • Real-time optical recording of β1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol

    Francesca Rochais;Jean-Pierre Vilardaga;Viacheslav O. Nikolaev;Moritz Bünemann

  • GLP-1 stimulates insulin secretion by PKC-dependent Trpm4 and Trpm5 activation

    Makoto Shigeto;Reshma Ramracheya;Andrei I. Tarasov;Chae Young Cha

  • Enhanced Expression of β3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase

    Catharina Belge;Joanna Hammond;Emilie Dubois-Deruy;Boris Manoury

Frequent Co-Authors

Martin J. Lohse
Martin J. Lohse ISAR Bioscience Institute
Jean-Pierre Vilardaga
Jean-Pierre Vilardaga University of Pittsburgh
Martina Schmidt
Martina Schmidt Johannes Gutenberg University of Mainz
Alexander R. Lyon
Alexander R. Lyon Imperial College London
Gerd Hasenfuss
Gerd Hasenfuss University of Göttingen
Laurinda A. Jaffe
Laurinda A. Jaffe University of Connecticut Health Center
Rodolphe Fischmeister
Rodolphe Fischmeister University of Paris-Saclay
Robert Feil
Robert Feil University of Tübingen
Thomas Eschenhagen
Thomas Eschenhagen Universität Hamburg
Dobromir Dobrev
Dobromir Dobrev University of Duisburg-Essen

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