Xin Yuan Guan

What is he best known for?

The fields of study he is best known for:

• Gene
• Cancer
• DNA

Xin Yuan Guan spends much of his time researching Cancer research, Metastasis, Pathology, Cancer and Molecular biology. Xin Yuan Guan studies Hepatocellular carcinoma, a branch of Cancer research. His Metastasis research includes themes of Cell migration, Oncology, Messenger RNA, microRNA and Vimentin.

His studies in Pathology integrate themes in fields like Epithelial–mesenchymal transition, Cell and In vivo. His biological study deals with issues like Downregulation and upregulation, which deal with fields such as Colorectal cancer. Xin Yuan Guan combines subjects such as Genetics, Fluorescence in situ hybridization, Chromosome, Chromosome microdissection and Gene duplication with his study of Molecular biology.

His most cited work include:

• Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer (2028 citations)
• AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer (1526 citations)
• Identification and characterization of tumorigenic liver cancer stem/progenitor cells. (956 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cancer research, Cancer, Metastasis, Pathology and Hepatocellular carcinoma. His research integrates issues of Cell growth, Carcinogenesis, Cancer stem cell, Downregulation and upregulation and Oncogene in his study of Cancer research. His study in Carcinogenesis is interdisciplinary in nature, drawing from both Molecular biology and Cell cycle.

His Cancer research is multidisciplinary, incorporating perspectives in microRNA and Oncology. His studies in Metastasis integrate themes in fields like Cell, Angiogenesis, Ectopic expression, Signal transduction and Regulation of gene expression. His study in Immunohistochemistry and Carcinoma is carried out as part of his studies in Pathology.

He most often published in these fields:

• Cancer research (76.88%)
• Cancer (30.00%)
• Metastasis (28.91%)

What were the highlights of his more recent work (between 2018-2021)?

• Cancer research (76.88%)
• Metastasis (28.91%)
• Hepatocellular carcinoma (22.81%)

In recent papers he was focusing on the following fields of study:

Xin Yuan Guan mainly investigates Cancer research, Metastasis, Hepatocellular carcinoma, Cell growth and Downregulation and upregulation. The concepts of his Cancer research study are interwoven with issues in Cancer, Tumor progression, Gene knockdown, Ectopic expression and Kinase. His work carried out in the field of Metastasis brings together such families of science as Osteosarcoma, Angiogenesis, Chromosomal translocation, Regulation of gene expression and Colorectal cancer.

His research in Hepatocellular carcinoma intersects with topics in Transcriptome, Stem cell and In vivo. The various areas that Xin Yuan Guan examines in his Cell growth study include Protein kinase B, Carcinogenesis, RNA, Gene silencing and Programmed cell death. His Downregulation and upregulation research is multidisciplinary, relying on both Chemoradiotherapy, Chemotherapy, Cancer cell, microRNA and PI3K/AKT/mTOR pathway.

Between 2018 and 2021, his most popular works were:

• N 6 -methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis (99 citations)
• N 6 -methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis (99 citations)
• APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production (56 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Cancer
• DNA

His primary scientific interests are in Cancer research, Metastasis, Downregulation and upregulation, Cell growth and Cancer cell. His Cancer research research focuses on Hepatocellular carcinoma in particular. His work deals with themes such as Angiogenesis, Carcinoma, Cell adhesion molecule, Loss of heterozygosity and Colorectal cancer, which intersect with Metastasis.

His research in Downregulation and upregulation focuses on subjects like Gene knockdown, which are connected to Oncogene, LRP6, Caveolin 1 and HBx. The study incorporates disciplines such as Lymphoid enhancer-binding factor 1, Receptor, Notch signaling pathway and HCCS in addition to Cell growth. His research investigates the connection with Cancer cell and areas like Cancer stem cell which intersect with concerns in PI3K/AKT/mTOR pathway, Cancer-Associated Fibroblasts, Crosstalk, Computational biology and Exosome.