World's Best Scientists 2026 revealed!
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Xin Yuan Guan

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Medicine 104 7006 6592 74 70 625 43810

Xin Yuan Guan publications per year

The chart shows the history of publications by Xin Yuan Guan between 1992 and 2021, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Xin Yuan Guan published across 30 years, from 1992 to 2021, averaging 20 papers a year. Output peaked at 42 publications in 2021. 68 of the 599 publications appeared in the last two years.

No. of publications
10 20 30 40
Bar chart. Horizontal axis: year, 1992 to 2021. Vertical axis: number of publications, 0 to 42. Peak 42 publications in 2021. 1992: 3 publications 1993: 10 publications 1994: 5 publications 1995: 10 publications 1996: 9 publications 1997: 7 publications 1998: 7 publications 1999: 11 publications 2000: 15 publications 2001: 11 publications 2002: 20 publications 2003: 17 publications 2004: 20 publications 2005: 26 publications 2006: 15 publications 2007: 18 publications 2008: 17 publications 2009: 28 publications 2010: 27 publications 2011: 33 publications 2012: 31 publications 2013: 22 publications 2014: 27 publications 2015: 30 publications 2016: 26 publications 2017: 29 publications 2018: 29 publications 2019: 28 publications 2020: 26 publications 2021: 42 publications
1992 2021

599 publications in total across all disciplines

View publications per year as a table
Xin Yuan Guan: publications per year, 1992 to 2021
Year Publications
1992 3
1993 10
1994 5
1995 10
1996 9
1997 7
1998 7
1999 11
2000 15
2001 11
2002 20
2003 17
2004 20
2005 26
2006 15
2007 18
2008 17
2009 28
2010 27
2011 33
2012 31
2013 22
2014 27
2015 30
2016 26
2017 29
2018 29
2019 28
2020 26
2021 42
Total 599
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Xin Yuan Guan publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Xin Yuan Guan sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 86 bars. Horizontal axis: publications, 101–120 to 1,796+. Vertical axis: number of scientists, 0 to 922. Most scientists, 922, have 341–360 publications. The last bar groups every scientist with 1,796 publications or more. The highlighted bar, 621–640 publications, is where this scientist sits. 101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 610 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101–120 publications 1,796+

This scientist: 625 publications — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

View publications distribution as a table
Number of Medicine scientists by publication count, Research.com 2026 ranking edition. Based on 20,134 ranked scientists.
Publications Scientists This scientist
101–120 5
121–140 26
141–160 73
161–180 155
181–200 230
201–220 363
221–240 487
241–260 545
261–280 722
281–300 768
301–320 834
321–340 895
341–360 922
361–380 838
381–400 861
401–420 918
421–440 806
441–460 771
461–480 751
481–500 713
501–520 617
521–540 610
541–560 537
561–580 504
581–600 509
601–620 396
621–640 386 625
641–660 371
661–680 340
681–700 336
701–720 307
721–740 259
741–760 230
761–780 228
781–800 217
801–820 204
821–840 186
841–860 177
861–880 155
881–900 139
901–920 145
921–940 116
941–960 133
961–980 91
981–1,000 96
1,001–1,020 77
1,021–1,040 70
1,041–1,060 63
1,061–1,080 77
1,081–1,100 49
1,101–1,120 54
1,121–1,140 49
1,141–1,160 51
1,161–1,180 35
1,181–1,200 39
1,201–1,220 26
1,221–1,240 37
1,241–1,260 36
1,261–1,280 27
1,281–1,300 32
1,301–1,320 28
1,321–1,340 17
1,341–1,360 30
1,361–1,380 28
1,381–1,400 17
1,401–1,420 21
1,421–1,440 15
1,441–1,460 12
1,461–1,480 12
1,481–1,500 18
1,501–1,520 14
1,521–1,540 17
1,541–1,560 15
1,561–1,580 6
1,581–1,600 2
1,601–1,620 12
1,621–1,640 11
1,641–1,660 8
1,661–1,680 5
1,681–1,700 5
1,701–1,720 10
1,721–1,740 12
1,741–1,760 14
1,761–1,780 6
1,781–1,795 5
1,796+ 100
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Xin Yuan Guan D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Xin Yuan Guan sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 75 bars. Horizontal axis: D-Index, 70–71 to 217+. Vertical axis: number of scientists, 0 to 1,027. Most scientists, 1,027, have 82–83 D-Index. The last bar groups every scientist with 217 D-Index or more. The highlighted bar, 104–105 D-Index, is where this scientist sits. 70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 399 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70–71 D-Index 217+

This scientist: 104 D-Index — 66th percentile

66% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

View D-Index distribution as a table
Number of Medicine scientists by D-index, Research.com 2026 ranking edition. Based on 20,134 ranked scientists.
D-Index Scientists This scientist
70–71 226
72–73 391
74–75 574
76–77 730
78–79 891
80–81 972
82–83 1,027
84–85 1,003
86–87 960
88–89 970
90–91 922
92–93 839
94–95 808
96–97 779
98–99 668
100–101 611
102–103 630
104–105 513 104
106–107 541
108–109 445
110–111 429
112–113 399
114–115 393
116–117 318
118–119 302
120–121 287
122–123 255
124–125 256
126–127 252
128–129 230
130–131 179
132–133 168
134–135 163
136–137 159
138–139 134
140–141 134
142–143 118
144–145 109
146–147 106
148–149 74
150–151 79
152–153 80
154–155 87
156–157 57
158–159 74
160–161 69
162–163 60
164–165 53
166–167 39
168–169 42
170–171 32
172–173 39
174–175 40
176–177 28
178–179 19
180–181 23
182–183 31
184–185 18
186–187 20
188–189 22
190–191 13
192–193 21
194–195 12
196–197 12
198–199 14
200–201 15
202–203 13
204–205 10
206–207 8
208–209 4
210–211 12
212–213 11
214–215 10
216 4
217+ 98
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Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

Xin Yuan Guan spends much of his time researching Cancer research, Metastasis, Pathology, Cancer and Molecular biology. Xin Yuan Guan studies Hepatocellular carcinoma, a branch of Cancer research. His Metastasis research includes themes of Cell migration, Oncology, Messenger RNA, microRNA and Vimentin.

His studies in Pathology integrate themes in fields like Epithelial–mesenchymal transition, Cell and In vivo. His biological study deals with issues like Downregulation and upregulation, which deal with fields such as Colorectal cancer. Xin Yuan Guan combines subjects such as Genetics, Fluorescence in situ hybridization, Chromosome, Chromosome microdissection and Gene duplication with his study of Molecular biology.

His most cited work include:

  • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer (2028 citations)
  • AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer (1526 citations)
  • Identification and characterization of tumorigenic liver cancer stem/progenitor cells. (956 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cancer research, Cancer, Metastasis, Pathology and Hepatocellular carcinoma. His research integrates issues of Cell growth, Carcinogenesis, Cancer stem cell, Downregulation and upregulation and Oncogene in his study of Cancer research. His study in Carcinogenesis is interdisciplinary in nature, drawing from both Molecular biology and Cell cycle.

His Cancer research is multidisciplinary, incorporating perspectives in microRNA and Oncology. His studies in Metastasis integrate themes in fields like Cell, Angiogenesis, Ectopic expression, Signal transduction and Regulation of gene expression. His study in Immunohistochemistry and Carcinoma is carried out as part of his studies in Pathology.

He most often published in these fields:

  • Cancer research (76.88%)
  • Cancer (30.00%)
  • Metastasis (28.91%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cancer research (76.88%)
  • Metastasis (28.91%)
  • Hepatocellular carcinoma (22.81%)

In recent papers he was focusing on the following fields of study:

Xin Yuan Guan mainly investigates Cancer research, Metastasis, Hepatocellular carcinoma, Cell growth and Downregulation and upregulation. The concepts of his Cancer research study are interwoven with issues in Cancer, Tumor progression, Gene knockdown, Ectopic expression and Kinase. His work carried out in the field of Metastasis brings together such families of science as Osteosarcoma, Angiogenesis, Chromosomal translocation, Regulation of gene expression and Colorectal cancer.

His research in Hepatocellular carcinoma intersects with topics in Transcriptome, Stem cell and In vivo. The various areas that Xin Yuan Guan examines in his Cell growth study include Protein kinase B, Carcinogenesis, RNA, Gene silencing and Programmed cell death. His Downregulation and upregulation research is multidisciplinary, relying on both Chemoradiotherapy, Chemotherapy, Cancer cell, microRNA and PI3K/AKT/mTOR pathway.

Between 2018 and 2021, his most popular works were:

  • N 6 -methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis (99 citations)
  • N 6 -methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis (99 citations)
  • APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production (56 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Cancer research, Metastasis, Downregulation and upregulation, Cell growth and Cancer cell. His Cancer research research focuses on Hepatocellular carcinoma in particular. His work deals with themes such as Angiogenesis, Carcinoma, Cell adhesion molecule, Loss of heterozygosity and Colorectal cancer, which intersect with Metastasis.

His research in Downregulation and upregulation focuses on subjects like Gene knockdown, which are connected to Oncogene, LRP6, Caveolin 1 and HBx. The study incorporates disciplines such as Lymphoid enhancer-binding factor 1, Receptor, Notch signaling pathway and HCCS in addition to Cell growth. His research investigates the connection with Cancer cell and areas like Cancer stem cell which intersect with concerns in PI3K/AKT/mTOR pathway, Cancer-Associated Fibroblasts, Crosstalk, Computational biology and Exosome.

Best Publications

  • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

    Fredrick S. Leach;Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu

  • AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer

    Sarah L. Anzick;Juha Kononen;Robert L. Walker;David O. Azorsa

  • Identification and characterization of tumorigenic liver cancer stem/progenitor cells.

    Stephanie Ma;Kwok–Wah Chan;Liang Hu;Terence Kin–Wah Lee

  • Comparative analyses of multi-species sequences from targeted genomic regions

    J. W. Thomas;J. W. Thomas;J. W. Touchman;R. W. Blakesley;G. G. Bouffard

  • Genomic instability in laminopathy-based premature aging

    Baohua Liu;Jianming Wang;Kui Ming Chan;Wai Mui Tjia

  • Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations

    Stephanie Ma;Kwok Wah Chan;Terence Kin-Wah Lee;Kwan Ho Tang

  • N 6 -methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

    Ri-Xin Chen;Xin Chen;Liang-Ping Xia;Jia-Xing Zhang

  • Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

    Leilei Chen;Yan Li;Chi Ho Lin;Tim Hon Man Chan;Tim Hon Man Chan

  • Twist Overexpression Correlates with Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition

    Terence K. Lee;Ronnie T.P. Poon;Anthony P. Yuen;Ming Tat Ling

  • miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

    Stephanie Ma;Kwan Ho Tang;Yuen Piu Chan;Terence K. Lee

  • The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2.

    Fang Zheng;Yi Ji Liao;Mu Yan Cai;Yan Hui Liu

  • A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability

    Shan Xiang Shen;Zoë Weaver;Xiaoling Xu;Cuiling Li

  • Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma

    Oscar W.H. Yeung;Chung Mau Lo;Chang Chun Ling;Xiang Qi

  • Rapid generation of region specific probes by chromosome microdissection and their application.

    Paul S. Meltzer;Xin Yuan Guan;Ann Burgess;Jeffrey M. Trent

  • MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression†‡

    Jian Hong Fang;Hui Chao Zhou;Chunxian Zeng;Jine Yang

  • Association of Vimentin overexpression and hepatocellular carcinoma metastasis

    Liang Hu;Sze Hang Lau;Chi Hung Tzang;Jian Ming Wen

  • Cancer stem cells in hepatocellular carcinoma - from origin to clinical implications.

    Terence Kin-Wah Lee;Xin-Yuan Guan;Xin-Yuan Guan;Stephanie Ma;Stephanie Ma

  • CD133+ liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling†‡

    Kwan Ho Tang;Stephanie Ma;Terence K. Lee;Yuen Piu Chan

  • MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor

    Kar Lok Kong;Dora Lai Wan Kwong;Tim Hon Man Chan;Simon Ying Kit Law

  • Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

    Stephanie Ma;Kwan Ho Tang;Yuen Piu Chan;Terence K. Lee

Frequent Co-Authors

Dan Xie
Dan Xie Sun Yat-sen University
Stephanie Ma
Stephanie Ma University of Hong Kong
Yi Xin Zeng
Yi Xin Zeng Sun Yat-sen University
Jonathan S.T. Sham
Jonathan S.T. Sham University of Hong Kong
Yan Li
Yan Li Sun Yat-sen University
Sai Wah Tsao
Sai Wah Tsao University of Hong Kong
Hsiang-Fu Kung
Hsiang-Fu Kung Chinese University of Hong Kong
Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute
Paul S. Meltzer
Paul S. Meltzer National Institutes of Health
Simon Law
Simon Law University of Hong Kong

External Links

Personal website of Xin Yuan Guan

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Best Scientists Citing Xin Yuan Guan

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Baylor College of Medicine

Publications: 97

Irene Oi-Lin Ng

Irene Oi-Lin Ng

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Publications: 75

Jianming Xu

Jianming Xu

Zhejiang University

Publications: 73

Dan Xie

Dan Xie

Sun Yat-sen University

Publications: 70

Sai Wah Tsao

Sai Wah Tsao

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Publications: 56

Henry T. Lynch

Henry T. Lynch

Creighton University

Publications: 54

Hongyang Wang

Hongyang Wang

Second Military Medical University

Publications: 41

Chu-Xia Deng

Chu-Xia Deng

University of Macau

Publications: 41

Bert Vogelstein

Bert Vogelstein

Johns Hopkins University

Publications: 39

Joe W. Gray

Joe W. Gray

Oregon Health & Science University

Publications: 39

Alfred King-Yin Lam

Alfred King-Yin Lam

Griffith University

Publications: 39

Jia Fan

Jia Fan

Fudan University

Publications: 38

Richard D. Kolodner

Richard D. Kolodner

University of California, San Diego

Publications: 38

Paul S. Meltzer

Paul S. Meltzer

National Institutes of Health

Publications: 37

Ronnie T.P. Poon

Ronnie T.P. Poon

University of Hong Kong

Publications: 35

Qian Tao

Qian Tao

Chinese University of Hong Kong

Publications: 35

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