World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
101
Citations
29873
World Ranking
8075
National Ranking
90

Overview

Dongxin Lin is a researcher affiliated with the Chinese Academy of Sciences in China. Their academic focus is primarily in the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. Lin's work spans numerous subfields including Molecular Biology, Oncology, Cancer Research, Surgery, and Genetics.

The scientist's recent scholarly publications illustrate a strong emphasis on cancer biology, molecular mechanisms, and transcriptomics. Selected papers include:

  • Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis, 2021, Nature Communications
  • Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming, 2020, Nature Communications
  • Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets, 2024, Signal Transduction and Targeted Therapy
  • A body map of somatic mutagenesis in morphologically normal human tissues, 2021, Nature
  • RNA m6A regulates transcription via DNA demethylation and chromatin accessibility, 2022, Nature Genetics

Frequent co-authors working alongside Dongxin Lin include:

  • Chen Wu (27 collaborations)
  • Wen Tan (19 collaborations)
  • Jian Zheng (18 collaborations)
  • Shaosen Zhang (14 collaborations)
  • Tianyuan Liu (13 collaborations)

Lin's publication venues represent well-established journals, highlighting the scientist's active presence in relevant academic circles. The most common venues are:

  • Nature Communications (7 publications)
  • Signal Transduction and Targeted Therapy (7 publications)
  • PubMed (7 publications)
  • Cancer Research (5 publications)
  • Cancer Cell (4 publications)

The scientist's research topics cover a variety of cancer-related and molecular biology themes. These main topics include:

  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Cancer-related gene regulation
  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Single-cell and spatial transcriptomics
  • Esophageal Cancer Research and Treatment

Best Publications

  • Identification of genomic alterations in oesophageal squamous cell cancer

    Yongmei Song;Lin Li;Yunwei Ou;Zhibo Gao

  • Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis.

    Jian Xu;Chen Wu;Xu Che;Li Wang

  • METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma

    Ting Li;Pei Shan Hu;Zhixiang Zuo;Jin Fei Lin

  • A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese

    Zhibin Hu;Chen Wu;Yongyong Shi;Huan Guo

  • Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers

    Hongxing Zhang;Yun Zhai;Zhibin Hu;Chen Wu

  • Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma

    Ling Zhang;Yong Zhou;Caixia Cheng;Heyang Cui

  • Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

    Qing Lan;Chao A. Hsiung;Keitaro Matsuo;Yun Chul Hong

  • Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma

    De Ke Jiang;Jielin Sun;Guangwen Cao;Yao Liu

  • Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population.

    Chunying Song;Deyin Xing;Wen Tan;Qingyi Wei

  • Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations

    Chen Wu;Zhibin Hu;Zhonghu He;Weihua Jia

  • Identification of Functional Genetic Variants in Cyclooxygenase-2 and Their Association With Risk of Esophageal Cancer

    Xuemei Zhang;Xuemei Zhang;Xiaoping Miao;Wen Tan;Baitang Ning

  • Genetic Polymorphisms of Interleukin (IL)-1B, IL-1RN, IL-8, IL-10, and Tumor Necrosis Factor α and Risk of Gastric Cancer in a Chinese population

    Wanli Lu;Kaifeng Pan;Lian Zhang;Dongxin Lin

  • A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers.

    Tong Sun;Yang Gao;Wen Tan;Sufang Ma

  • Excessive miR-25-3p maturation via N 6 -methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression

    Jialiang Zhang;Ruihong Bai;Mei Li;Huilin Ye

  • Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma.

    Bingtao Hao;Haijian Wang;Kaixin Zhou;Yi Li

  • A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1

    Yongyong Shi;Zhibin Hu;Chen Wu;Juncheng Dai

  • Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

    Chen Wu;Chen Wu;Peter Kraft;Kan Zhai;Jiang Chang

  • Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma.

    Tong Sun;Xiaoping Miao;Xuemei Zhang;Wen Tan

  • Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation

    Jian Zheng;Xudong Huang;Wen Tan;Dianke Yu

  • Fen1 mutations result in autoimmunity, chronic inflammation and cancers

    Li Zheng;Huifang Dai;Mian Zhou;Mei Li

Frequent Co-Authors

Wen Tan
Wen Tan Peking Union Medical College Hospital
Chen Wu
Chen Wu Peking Union Medical College Hospital
Xiaoping Miao
Xiaoping Miao Huazhong University of Science and Technology
Hongbing Shen
Hongbing Shen Nanjing Medical University
Zhibin Hu
Zhibin Hu Nanjing Medical University
Jiang Chang
Jiang Chang University of Chinese Academy of Sciences
Guangfu Jin
Guangfu Jin Nanjing Medical University
Stephen J. Chanock
Stephen J. Chanock National Institutes of Health
Xiao-Ou Shu
Xiao-Ou Shu Vanderbilt University Medical Center
Jianjun Liu
Jianjun Liu Genome Institute of Singapore

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